PDB: 1hrk Compound: ferrochelatase Classification: LYASE Entry date in PDB: 2001-06-22 Resolution [Å]: 2.00 R-Factor: 0.202

CHAIN: A SWISS-PROT/TREMBL: P22830    KEYWORD: 2Fe-2S    3D-structure    Disease mutation    Heme biosynthesis    Iron    Iron-sulfur    Lyase    Metal-binding    Mitochondrion    Polymorphism    Porphyrin biosynthesis    Transit peptide    EC: 4.99.1.1 SCOP: c.92.1.1 Alpha and beta proteins (a/b)    Chelatase-like    Chelatase    Ferrochelatase    Ferrochelatase    Human (Homo sapiens) GO:   CHAIN: B SWISS-PROT/TREMBL: P22830    KEYWORD: 2Fe-2S    3D-structure    Disease mutation    Heme biosynthesis    Iron    Iron-sulfur    Lyase    Metal-binding    Mitochondrion    Polymorphism    Porphyrin biosynthesis    Transit peptide    EC: 4.99.1.1 SCOP: c.92.1.1 Alpha and beta proteins (a/b)    Chelatase-like    Chelatase    Ferrochelatase    Ferrochelatase    Human (Homo sapiens) GO:

Image Source: PDB

Loops in ArchDB40 clusters

1hrk_A_170 - HE => SUBCLASS : 3.1.1
1hrk_A_315 - HE => SUBCLASS : 3.6.1
1hrk_A_315 - HE => SUBCLASS : 3.6.7
1hrk_A_356 - HE => SUBCLASS : 4.15.1
1hrk_A_199 - HE => SUBCLASS : 5.24.1
1hrk_A_257 - EH => SUBCLASS : 1.1.21
1hrk_A_257 - EH => SUBCLASS : 3.5.5

Loops in ArchDB95 clusters

1hrk_A_257 - EH => SUBCLASS : 1.1.16
1hrk_A_257 - EH => SUBCLASS : 3.7.2
1hrk_A_184 - EH => SUBCLASS : 6.50.1
1hrk_A_69 - EH => SUBCLASS : 6.51.1
1hrk_A_157 - EH => SUBCLASS : 6.72.1
1hrk_A_329 - EH => SUBCLASS : 8.36.1
1hrk_A_315 - HE => SUBCLASS : 3.1.1
1hrk_A_170 - HE => SUBCLASS : 3.1.1
1hrk_A_356 - HE => SUBCLASS : 3.1.3
1hrk_A_276 - HE => SUBCLASS : 5.56.1
1hrk_A_199 - HE => SUBCLASS : 6.21.1

Loops in ArchDB-EC clusters

1hrk_A_231 - HE => SUBCLASS : 8.7.1

Loops not clustered in ArchDB

1hrk_A_220 - EH
1hrk_A_297 - EH
1hrk_A_364 - EH
1hrk_A_132 - HE
1hrk_A_85 - HH
1hrk_A_104 - HH
1hrk_A_267 - HH
1hrk_A_342 - HH
1hrk_A_375 - HH

1hrk A - percentage of sequence identity: 100
1hrk B - percentage of sequence identity: 100