PDB: 1i2s Compound: beta-lactamase Classification: HYDROLASE Entry date in PDB: 2002-03-13 Resolution [Å]: 1.70 R-Factor: 0.197

CHAIN: A SWISS-PROT/TREMBL: P00808    KEYWORD: 3D-structure    Antibiotic resistance    Hydrolase    Lipoprotein    Membrane    Palmitate    Signal    EC: 3.5.2.6 SCOP: e.3.1.1 Multi-domain proteins (alpha and beta)    beta-lactamase/transpeptidase-like    beta-lactamase/transpeptidase-like    beta-Lactamase/D-ala carboxypeptidase    beta-Lactamase, class A    Bacillus licheniformis GO:  beta-lactamase activity    beta-lactam antibiotic catabolism    response to antibiotic    CHAIN: B SWISS-PROT/TREMBL: P00808    KEYWORD: 3D-structure    Antibiotic resistance    Hydrolase    Lipoprotein    Membrane    Palmitate    Signal    EC: 3.5.2.6 SCOP: e.3.1.1 Multi-domain proteins (alpha and beta)    beta-lactamase/transpeptidase-like    beta-lactamase/transpeptidase-like    beta-Lactamase/D-ala carboxypeptidase    beta-Lactamase, class A    Bacillus licheniformis GO:  beta-lactamase activity    beta-lactam antibiotic catabolism    response to antibiotic

Image Source: PDB

Loops in ArchDB95 clusters

1i2s_A_180 - EH => SUBCLASS : 1.1.2
1i2s_A_66 - EH => SUBCLASS : 2.7.1
1i2s_A_259 - EH => SUBCLASS : 8.6.1
1i2s_A_55 - AR => SUBCLASS : 5.10.1
1i2s_A_119 - HH => SUBCLASS : 2.2.1
1i2s_A_119 - HH => SUBCLASS : 2.2.3
1i2s_A_132 - HH => SUBCLASS : 2.6.1
1i2s_A_183 - HH => SUBCLASS : 5.12.1
1i2s_A_201 - HH => SUBCLASS : 7.7.1
1i2s_A_230 - HA => SUBCLASS : 2.1.5
1i2s_A_230 - HA => SUBCLASS : 3.2.1
1i2s_A_43 - HA => SUBCLASS : 4.1.1
1i2s_A_243 - HA => SUBCLASS : 6.30.1

Loops in ArchDB-EC clusters

1i2s_A_201 - HH => SUBCLASS : 7.6.1

Loops not clustered in ArchDB

1i2s_A_55 - AR
1i2s_A_117 - EH
1i2s_A_230 - HA
1i2s_A_94 - HA
1i2s_A_43 - HA
1i2s_A_94 - HA
1i2s_A_243 - HA
1i2s_A_221 - HE
1i2s_A_145 - HE
1i2s_A_72 - HE
1i2s_A_32 - HE

1i2s A - percentage of sequence identity: 100
1i2s B - percentage of sequence identity: 100
1i2w A - percentage of sequence identity: 100
1i2w B - percentage of sequence identity: 100
1mbl A - percentage of sequence identity: 96
1mbl B - percentage of sequence identity: 96
2blm A - percentage of sequence identity: 97
2blm B - percentage of sequence identity: 97
4blm A - percentage of sequence identity: 97
4blm B - percentage of sequence identity: 97