PDB: 1j8f Compound: sirtuin 2, isoform 1 Classification: GENE REGULATION, TRANSFERASE Entry date in PDB: 2001-07-06 Resolution [Å]: 1.70 R-Factor: 0.235

CHAIN: A SWISS-PROT/TREMBL: Q8IXJ6    KEYWORD: 3D-structure    Alternative splicing    Cell cycle    Cytoskeleton    Hydrolase    Metal-binding    Microtubule    Mitosis    NAD    Phosphorylation    Zinc    EC: 3.5.1.- SCOP: c.31.1.5 Alpha and beta proteins (a/b)    DHS-like NAD/FAD-binding domain    DHS-like NAD/FAD-binding domain    Sir2 family of transcriptional regulators    Sirt2 histone deacetylase    Human (Homo sapiens) GO:  chromatin silencing complex    DNA binding    chromatin silencing    regulation of transcription, DNA-dependent    CHAIN: B SWISS-PROT/TREMBL: Q8IXJ6    KEYWORD: 3D-structure    Alternative splicing    Cell cycle    Cytoskeleton    Hydrolase    Metal-binding    Microtubule    Mitosis    NAD    Phosphorylation    Zinc    EC: 3.5.1.- SCOP: c.31.1.5 Alpha and beta proteins (a/b)    DHS-like NAD/FAD-binding domain    DHS-like NAD/FAD-binding domain    Sir2 family of transcriptional regulators    Sirt2 histone deacetylase    Human (Homo sapiens) GO:  chromatin silencing complex    DNA binding    chromatin silencing    regulation of transcription, DNA-dependent    CHAIN: C SWISS-PROT/TREMBL: Q8IXJ6    KEYWORD: 3D-structure    Alternative splicing    Cell cycle    Cytoskeleton    Hydrolase    Metal-binding    Microtubule    Mitosis    NAD    Phosphorylation    Zinc    EC: 3.5.1.- SCOP: c.31.1.5 Alpha and beta proteins (a/b)    DHS-like NAD/FAD-binding domain    DHS-like NAD/FAD-binding domain    Sir2 family of transcriptional regulators    Sirt2 histone deacetylase    Human (Homo sapiens) GO:  chromatin silencing complex    DNA binding    chromatin silencing    regulation of transcription, DNA-dependent

Image Source: PDB

Loops in ArchDB40 clusters

1j8f_A_183 - HA => SUBCLASS : 2.2.41
1j8f_A_203 - EH => SUBCLASS : 1.1.13
1j8f_A_317 - EH => SUBCLASS : 2.5.1
1j8f_A_317 - EH => SUBCLASS : 2.5.2
1j8f_A_324 - HH => SUBCLASS : 1.3.2

Loops in ArchDB95 clusters

1j8f_A_203 - EH => SUBCLASS : 1.1.11
1j8f_A_317 - EH => SUBCLASS : 2.5.1
1j8f_A_161 - EH => SUBCLASS : 5.77.1
1j8f_A_121 - HH => SUBCLASS : 1.2.4
1j8f_A_324 - HH => SUBCLASS : 1.3.2
1j8f_A_324 - HH => SUBCLASS : 1.3.3
1j8f_A_147 - HE => SUBCLASS : 2.4.1
1j8f_A_64 - HE => SUBCLASS : 5.2.8
1j8f_A_172 - HE => SUBCLASS : 6.2.8
1j8f_A_267 - HE => SUBCLASS : 6.41.1
1j8f_A_183 - HA => SUBCLASS : 2.2.32

Loops in ArchDB-EC clusters

1j8f_A_324 - HH => SUBCLASS : 1.3.2

Loops not clustered in ArchDB

1j8f_A_79 - EH
1j8f_A_228 - EH
1j8f_A_256 - EH
1j8f_A_282 - EH
1j8f_A_183 - HA
1j8f_A_188 - HA
1j8f_A_188 - HA
1j8f_A_241 - HE
1j8f_A_206 - HE
1j8f_A_295 - HE
1j8f_A_35 - HH
1j8f_A_129 - HH

1j8f A - percentage of sequence identity: 100
1j8f B - percentage of sequence identity: 100
1j8f C - percentage of sequence identity: 100