PDB: 1k6m Compound: 6-phosphofructo-2-kinaseFRUCTOSE-2,6- biphosphatas Classification: TRANSFERASE, HYDROLASE Entry date in PDB: 2002-12-11 Resolution [Å]: 2.40 R-Factor: 0.217

CHAIN: A SWISS-PROT/TREMBL: P16118    KEYWORD: 3D-structure    ATP-binding    Hydrolase    Kinase    Multifunctional enzyme    Multigene family    Phosphorylation    Transferase    EC: 2.7.1.105 SCOP: c.37.1.7 Alpha and beta proteins (a/b)    P-loop containing nucleoside triphosphate hydrolases    P-loop containing nucleoside triphosphate hydrolases    6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain    6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain    Human (Homo sapiens) SCOP: c.60.1.4 Alpha and beta proteins (a/b)    Phosphoglycerate mutase-like    Phosphoglycerate mutase-like    6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain    6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain    Human (Homo sapiens) GO:  ATP binding    catalytic activity    fructose 2,6-bisphosphate metabolism    metabolism    CHAIN: B SWISS-PROT/TREMBL: P16118    KEYWORD: 3D-structure    ATP-binding    Hydrolase    Kinase    Multifunctional enzyme    Multigene family    Phosphorylation    Transferase    EC: 2.7.1.105 SCOP: c.37.1.7 Alpha and beta proteins (a/b)    P-loop containing nucleoside triphosphate hydrolases    P-loop containing nucleoside triphosphate hydrolases    6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain    6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain    Human (Homo sapiens) SCOP: c.60.1.4 Alpha and beta proteins (a/b)    Phosphoglycerate mutase-like    Phosphoglycerate mutase-like    6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain    6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain    Human (Homo sapiens) GO:  ATP binding    catalytic activity    fructose 2,6-bisphosphate metabolism    metabolism

Image Source: PDB

Loops in ArchDB95 clusters

1k6m_A_299 - EH => SUBCLASS : 2.1.2
1k6m_A_299 - EH => SUBCLASS : 2.3.2
1k6m_A_262 - HH => SUBCLASS : 10.21.1
1k6m_A_136 - HE => SUBCLASS : 1.1.1
1k6m_A_54 - HE => SUBCLASS : 2.1.1
1k6m_A_98 - HE => SUBCLASS : 3.1.1
1k6m_A_54 - HE => SUBCLASS : 3.2.7
1k6m_A_306 - HE => SUBCLASS : 3.2.9
1k6m_A_393 - HE => SUBCLASS : 15.3.1
1k6m_A_216 - HA => SUBCLASS : 4.6.1

Loops not clustered in ArchDB

1k6m_A_431 - EH
1k6m_A_42 - EH
1k6m_A_72 - EH
1k6m_A_126 - EH
1k6m_A_152 - EH
1k6m_A_225 - EH
1k6m_A_253 - EH
1k6m_A_320 - EH
1k6m_A_387 - EH
1k6m_A_420 - HA
1k6m_A_186 - HE
1k6m_A_234 - HE
1k6m_A_277 - HE
1k6m_A_367 - HE
1k6m_A_77 - HH
1k6m_A_163 - HH
1k6m_A_338 - HH
1k6m_A_346 - HH

1bif - - percentage of sequence identity: 78
1c7z A - percentage of sequence identity: 95
1c7z B - percentage of sequence identity: 95
1c80 A - percentage of sequence identity: 95
1c80 B - percentage of sequence identity: 95
1c81 A - percentage of sequence identity: 95
1fbt A - percentage of sequence identity: 95
1fbt B - percentage of sequence identity: 95
1k6m A - percentage of sequence identity: 100
1k6m B - percentage of sequence identity: 100
1tip A - percentage of sequence identity: 95
1tip B - percentage of sequence identity: 95
2axn A - percentage of sequence identity: 72
2bif A - percentage of sequence identity: 78
2bif B - percentage of sequence identity: 78
3bif A - percentage of sequence identity: 78