PDB: 1kny Compound: kanamycin nucleotidyltransferase Classification: TRANSFERASE Entry date in PDB: 1996-08-17 Resolution [Å]: 2.50 R-Factor: 0.168

CHAIN: A SWISS-PROT/TREMBL: P05057    KEYWORD: 3D-structure    Antibiotic resistance    Plasmid    Transferase    EC: 2.7.7.- SCOP: a.24.16.1 All alpha proteins    Four-helical up-and-down bundle    Nucleotidyltransferase substrate binding subunit/domain    Kanamycin nucleotidyltransferase (KNTase), C-terminal domain    Kanamycin nucleotidyltransferase (KNTase), C-terminal domain    Staphylococcus aureus SCOP: d.218.1.1 Alpha and beta proteins (a+b)    Nucleotidyltransferase    Nucleotidyltransferase    Kanamycin nucleotidyltransferase (KNTase), N-terminal domain    Kanamycin nucleotidyltransferase (KNTase), N-terminal domain    Staphylococcus aureus GO:  nucleotidyltransferase activity    CHAIN: B SWISS-PROT/TREMBL: P05057    KEYWORD: 3D-structure    Antibiotic resistance    Plasmid    Transferase    EC: 2.7.7.- SCOP: a.24.16.1 All alpha proteins    Four-helical up-and-down bundle    Nucleotidyltransferase substrate binding subunit/domain    Kanamycin nucleotidyltransferase (KNTase), C-terminal domain    Kanamycin nucleotidyltransferase (KNTase), C-terminal domain    Staphylococcus aureus SCOP: d.218.1.1 Alpha and beta proteins (a+b)    Nucleotidyltransferase    Nucleotidyltransferase    Kanamycin nucleotidyltransferase (KNTase), N-terminal domain    Kanamycin nucleotidyltransferase (KNTase), N-terminal domain    Staphylococcus aureus GO:  nucleotidyltransferase activity

Image Source: PDB

Loops in ArchDB40 clusters

1kny_A_9 - HE => SUBCLASS : 3.11.1
1kny_A_63 - HA => SUBCLASS : 3.3.1
1kny_A_107 - EH => SUBCLASS : 3.17.3
1kny_A_51 - AR => SUBCLASS : 5.22.1

Loops in ArchDB95 clusters

1kny_A_107 - EH => SUBCLASS : 3.17.4
1kny_A_51 - AR => SUBCLASS : 4.10.2
1kny_A_9 - HE => SUBCLASS : 3.11.1
1kny_A_63 - HA => SUBCLASS : 3.6.1

Loops in ArchDB-EC clusters

1kny_A_9 - HE => SUBCLASS : 3.15.1

Loops not clustered in ArchDB

1kny_A_51 - AR
1kny_A_31 - EH
1kny_A_74 - EH
1kny_A_63 - HA
1kny_A_96 - HE
1kny_A_38 - HE
1kny_A_82 - HH
1kny_A_115 - HH
1kny_A_143 - HH
1kny_A_162 - HH
1kny_A_191 - HH
1kny_A_205 - HH
1kny_A_128 - HH

1kan A - percentage of sequence identity: 99
1kan B - percentage of sequence identity: 99
1kny A - percentage of sequence identity: 100
1kny B - percentage of sequence identity: 100