PDB: 1n8z Compound: herceptin fab (antibody) - light chain Classification: TRANSFERASE Entry date in PDB: 2003-02-18 Resolution [Å]: 2.52 R-Factor: 0.225

CHAIN: C SWISS-PROT/TREMBL: P04626    KEYWORD: 3D-structure    ATP-binding    Glycoprotein    Multigene family    Phosphorylation    Polymorphism    Receptor    Signal    Transferase    Transmembrane    Tyrosine-protein kinase    EC: 2.7.1.112 SCOP: c.10.2.5 Alpha and beta proteins (a/b)    Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)    L domain-like    L domain    Protooncoprotein Her2 extracellular domain    Human (Homo sapiens) SCOP: c.10.2.5 Alpha and beta proteins (a/b)    Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)    L domain-like    L domain    Protooncoprotein Her2 extracellular domain    Human (Homo sapiens) SCOP: g.3.9.1 Small proteins    Knottins (small inhibitors, toxins, lectins)    Growth factor receptor domain    Growth factor receptor domain    Protooncoprotein Her2 extracellular domain    Human (Homo sapiens) SCOP: g.3.9.1 Small proteins    Knottins (small inhibitors, toxins, lectins)    Growth factor receptor domain    Growth factor receptor domain    Protooncoprotein Her2 extracellular domain    Human (Homo sapiens) GO:  membrane    ATP binding    epidermal growth factor receptor activity    protein kinase activity    protein-tyrosine kinase activity    transmembrane receptor protein tyrosine kinase activity    protein amino acid phosphorylation    transmembrane receptor protein tyrosine kinase signaling pathway

Image Source: PDB

Loops in ArchDB-EC clusters

1n8z_C_147 - HE => SUBCLASS : 9.8.1

Loops not clustered in ArchDB

1n8z_C_408 - AR
1n8z_C_125 - AR
1n8z_C_160 - AR
1n8z_C_307 - AR
1n8z_C_241 - AR
1n8z_C_517 - AR
1n8z_C_259 - AR
1n8z_C_419 - AR
1n8z_C_272 - AR
1n8z_C_438 - AR
1n8z_C_90 - AR
1n8z_C_79 - AR
1n8z_C_62 - AR
1n8z_C_388 - AR
1n8z_C_383 - AR
1n8z_C_352 - AR
1n8z_C_573 - AR
1n8z_C_347 - AR
1n8z_C_537 - AR
1n8z_C_33 - AR
1n8z_C_38 - AR
1n8z_C_57 - AR
1n8z_C_289 - AR
1n8z_C_3 - EH
1n8z_C_471 - EH
1n8z_C_443 - EH
1n8z_C_130 - EH
1n8z_C_512 - HA
1n8z_C_568 - HA
1n8z_C_531 - HA
1n8z_C_297 - HA
1n8z_C_282 - HA
1n8z_C_267 - HA
1n8z_C_250 - HA
1n8z_C_236 - HA
1n8z_C_593 - HA
1n8z_C_479 - HE
1n8z_C_460 - HE
1n8z_C_17 - HE

12e8 H - percentage of sequence identity: 61
1a0q L - percentage of sequence identity: 61
1a3r L - percentage of sequence identity: 60
1a4k H - percentage of sequence identity: 72
1a7q L - percentage of sequence identity: 62
1ad0 A - percentage of sequence identity: 88
1b0w A - percentage of sequence identity: 78
1bww A - percentage of sequence identity: 79
1bz7 A - percentage of sequence identity: 82
1c5c H - percentage of sequence identity: 74
1c5d A - percentage of sequence identity: 65
1ce1 H - percentage of sequence identity: 75
1clo L - percentage of sequence identity: 61
1cz8 H - percentage of sequence identity: 79
1d5i L - percentage of sequence identity: 82
1dqd L - percentage of sequence identity: 62
1dsf H - percentage of sequence identity: 66
1dzb A - percentage of sequence identity: 64
1eeq A - percentage of sequence identity: 65
1ejo H - percentage of sequence identity: 62
1ek3 A - percentage of sequence identity: 68
1emt L - percentage of sequence identity: 64
1f2x K - percentage of sequence identity: 60
1f4x H - percentage of sequence identity: 65
1fe8 L - percentage of sequence identity: 62
1fgn H - percentage of sequence identity: 62
1fgv L - percentage of sequence identity: 86
1fl5 B - percentage of sequence identity: 83
1flr H - percentage of sequence identity: 63
1fns L - percentage of sequence identity: 66
1fvc B - percentage of sequence identity: 100
1gaf L - percentage of sequence identity: 84
1h8n A - percentage of sequence identity: 68
1hcv - - percentage of sequence identity: 61
1hyx H - percentage of sequence identity: 61
1i7z A - percentage of sequence identity: 80
1igm L - percentage of sequence identity: 80
1ikf H - percentage of sequence identity: 63
1il1 B - percentage of sequence identity: 60
1ind H - percentage of sequence identity: 60
1iqd A - percentage of sequence identity: 81
1iqw L - percentage of sequence identity: 61
1j05 B - percentage of sequence identity: 63
1jfq L - percentage of sequence identity: 64
1jgu H - percentage of sequence identity: 63
1jhl L - percentage of sequence identity: 68
1jpt H - percentage of sequence identity: 87
1k6q H - percentage of sequence identity: 61
1kcu L - percentage of sequence identity: 61
1kcv L - percentage of sequence identity: 61
1kel H - percentage of sequence identity: 66
1kxq E - percentage of sequence identity: 61
1kxt B - percentage of sequence identity: 60
1l7i L - percentage of sequence identity: 94
1l7t H - percentage of sequence identity: 64
1lk3 L - percentage of sequence identity: 61
1mam L - percentage of sequence identity: 65
1mex L - percentage of sequence identity: 62
1mqk H - percentage of sequence identity: 66
1n0x H - percentage of sequence identity: 71
1n7m H - percentage of sequence identity: 84
1nbv H - percentage of sequence identity: 65
1nmb L - percentage of sequence identity: 67
1ohq A - percentage of sequence identity: 75
1ol0 A - percentage of sequence identity: 69
1op3 H - percentage of sequence identity: 76
1op9 A - percentage of sequence identity: 65
1ors A - percentage of sequence identity: 61
1q9r A - percentage of sequence identity: 60
1q9w B - percentage of sequence identity: 64
1qkz H - percentage of sequence identity: 64
1qok A - percentage of sequence identity: 61
1r3j A - percentage of sequence identity: 60
1rhh A - percentage of sequence identity: 81
1rz7 H - percentage of sequence identity: 75
1rz8 A - percentage of sequence identity: 83
1rzf H - percentage of sequence identity: 70
1rzg A - percentage of sequence identity: 69
1s78 A - percentage of sequence identity: 100
1s78 B - percentage of sequence identity: 100
1sbs L - percentage of sequence identity: 61
1sm3 H - percentage of sequence identity: 64
1ub5 A - percentage of sequence identity: 61
1ucb H - percentage of sequence identity: 79
1vge H - percentage of sequence identity: 73
1wej H - percentage of sequence identity: 62
1wtl A - percentage of sequence identity: 79
2ck0 L - percentage of sequence identity: 60
2f5b H - percentage of sequence identity: 65
2h1p H - percentage of sequence identity: 61
2hrp H - percentage of sequence identity: 67
2imn - - percentage of sequence identity: 64
35c8 H - percentage of sequence identity: 62
43c9 A - percentage of sequence identity: 61
8fab B - percentage of sequence identity: 81