PDB: 1now Compound: beta-hexosaminidase beta chain Classification: HYDROLASE Entry date in PDB: 2003-04-29 Resolution [Å]: 2.20 R-Factor: 0.194

CHAIN: A SWISS-PROT/TREMBL: P07686    KEYWORD: 3D-structure    Disease mutation    Glycoprotein    Glycosidase    GM2-gangliosidosis    Hydrolase    Lysosome    Polymorphism    Signal    Zymogen    EC: 3.2.1.52 SCOP: c.1.8.6 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    (Trans)glycosidases    beta-N-acetylhexosaminidase catalytic domain    beta-hexosaminidase B    Human (Homo sapiens) SCOP: d.92.2.1 Alpha and beta proteins (a+b)    Zincin-like    beta-N-acetylhexosaminidase-like domain    beta-N-acetylhexosaminidase domain    beta-hexosaminidase B, N-terminal domain    Human (Homo sapiens) GO:  beta-N-acetylhexosaminidase activity    carbohydrate metabolism    CHAIN: B SWISS-PROT/TREMBL: P07686    KEYWORD: 3D-structure    Disease mutation    Glycoprotein    Glycosidase    GM2-gangliosidosis    Hydrolase    Lysosome    Polymorphism    Signal    Zymogen    EC: 3.2.1.52 SCOP: c.1.8.6 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    (Trans)glycosidases    beta-N-acetylhexosaminidase catalytic domain    beta-hexosaminidase B    Human (Homo sapiens) SCOP: d.92.2.1 Alpha and beta proteins (a+b)    Zincin-like    beta-N-acetylhexosaminidase-like domain    beta-N-acetylhexosaminidase domain    beta-hexosaminidase B, N-terminal domain    Human (Homo sapiens) GO:  beta-N-acetylhexosaminidase activity    carbohydrate metabolism

Image Source: PDB

Loops in ArchDB40 clusters

1now_A_180 - HA => SUBCLASS : 4.2.2
1now_A_401 - EH => SUBCLASS : 0.1.11
1now_A_157 - EH => SUBCLASS : 2.1.1
1now_A_202 - EH => SUBCLASS : 7.26.1
1now_A_187 - AR => SUBCLASS : 4.34.1
1now_A_62 - AR => SUBCLASS : 5.3.1
1now_A_498 - HH => SUBCLASS : 2.16.1

Loops in ArchDB95 clusters

1now_A_401 - EH => SUBCLASS : 0.1.5
1now_A_401 - EH => SUBCLASS : 0.1.33
1now_A_401 - EH => SUBCLASS : 0.1.40
1now_A_157 - EH => SUBCLASS : 2.1.1
1now_A_481 - EH => SUBCLASS : 6.9.2
1now_A_202 - EH => SUBCLASS : 7.40.1
1now_A_62 - AR => SUBCLASS : 3.2.1
1now_A_187 - AR => SUBCLASS : 4.21.1
1now_A_498 - HH => SUBCLASS : 2.14.1
1now_A_180 - HA => SUBCLASS : 3.1.2
1now_A_180 - HA => SUBCLASS : 5.1.1
1now_A_180 - HA => SUBCLASS : 5.1.2

Loops in ArchDB-EC clusters

1now_A_359 - HH => SUBCLASS : 1.1.6

Loops not clustered in ArchDB

1now_A_126 - AR
1now_A_62 - AR
1now_A_126 - AR
1now_A_187 - AR
1now_A_348 - EH
1now_A_233 - EH
1now_A_284 - EH
1now_A_78 - EH
1now_A_319 - EH
1now_A_443 - EH
1now_A_420 - EH
1now_A_180 - HA
1now_A_306 - HA
1now_A_149 - HA
1now_A_149 - HA
1now_A_306 - HA
1now_A_475 - HE
1now_A_92 - HE
1now_A_165 - HE
1now_A_216 - HE
1now_A_268 - HE
1now_A_298 - HE
1now_A_327 - HE
1now_A_380 - HE
1now_A_407 - HE
1now_A_429 - HE
1now_A_505 - HH
1now_A_460 - HH
1now_A_365 - HH
1now_A_252 - HH

1nou A - percentage of sequence identity: 100
1nou B - percentage of sequence identity: 100
1now A - percentage of sequence identity: 100
1now B - percentage of sequence identity: 100
1np0 A - percentage of sequence identity: 100
1np0 B - percentage of sequence identity: 100
1o7a A - percentage of sequence identity: 100
1o7a B - percentage of sequence identity: 100
1o7a C - percentage of sequence identity: 100
1o7a D - percentage of sequence identity: 100
1o7a E - percentage of sequence identity: 100
1o7a F - percentage of sequence identity: 100