PDB: 1ns3 Compound: ns3 protease Classification: COMPLEX (HYDROLASE/PEPTIDE) Entry date in PDB: 1998-04-08 Resolution [Å]: 2.80 R-Factor: 0.204

CHAIN: A SWISS-PROT/TREMBL: P26663    KEYWORD: 3D-structure    ATP-binding    Coat protein    Core protein    Envelope protein    Glycoprotein    Helicase    Hydrolase    Nonstructural protein    Polyprotein    RNA-directed RNA polymerase    Serine protease    Transferase    Transmembrane    EC: 2.7.7.48 SCOP: b.47.1.3 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Viral proteases    NS3 protease    Human hepatitis C virus (HCV), different isolates GO:  viral capsid    viral envelope    ATP binding    ATP-dependent helicase activity    helicase activity    nucleic acid binding    RNA binding    RNA-directed RNA polymerase activity    serine-type peptidase activity    structural molecule activity    proteolysis and peptidolysis    transcription    viral genome replication    viral transformation    CHAIN: B SWISS-PROT/TREMBL: P26663    KEYWORD: 3D-structure    ATP-binding    Coat protein    Core protein    Envelope protein    Glycoprotein    Helicase    Hydrolase    Nonstructural protein    Polyprotein    RNA-directed RNA polymerase    Serine protease    Transferase    Transmembrane    EC: 2.7.7.48 SCOP: b.47.1.3 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Viral proteases    NS3 protease    Human hepatitis C virus (HCV), different isolates GO:  viral capsid    viral envelope    ATP binding    ATP-dependent helicase activity    helicase activity    nucleic acid binding    RNA binding    RNA-directed RNA polymerase activity    serine-type peptidase activity    structural molecule activity    proteolysis and peptidolysis    transcription    viral genome replication    viral transformation    CHAIN: C SWISS-PROT/TREMBL: P29846    KEYWORD: 3D-structure    ATP-binding    Coat protein    Core protein    Envelope protein    Glycoprotein    Helicase    Hydrolase    Nonstructural protein    Polyprotein    RNA-directed RNA polymerase    Serine protease    Transferase    Transmembrane    EC: 2.7.7.48 SCOP: b.47.1.3 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Viral proteases    NS3 protease    Human hepatitis C virus (HCV), different isolates GO:  viral capsid    viral envelope    ATP binding    ATP-dependent helicase activity    helicase activity    nucleic acid binding    RNA binding    RNA-directed RNA polymerase activity    serine-type peptidase activity    structural molecule activity    proteolysis and peptidolysis    transcription    viral genome replication    viral transformation    CHAIN: D SWISS-PROT/TREMBL: P29846    KEYWORD: 3D-structure    ATP-binding    Coat protein    Core protein    Envelope protein    Glycoprotein    Helicase    Hydrolase    Nonstructural protein    Polyprotein    RNA-directed RNA polymerase    Serine protease    Transferase    Transmembrane    EC: 2.7.7.48 SCOP: b.47.1.3 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Viral proteases    NS3 protease    Human hepatitis C virus (HCV), different isolates GO:  viral capsid    viral envelope    ATP binding    ATP-dependent helicase activity    helicase activity    nucleic acid binding    RNA binding    RNA-directed RNA polymerase activity    serine-type peptidase activity    structural molecule activity    proteolysis and peptidolysis    transcription    viral genome replication    viral transformation

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1a1r A - percentage of sequence identity: 89
1cu1 A - percentage of sequence identity: 99
1dy9 A - percentage of sequence identity: 96