PDB: 1nwc Compound: aspartate-semialdehyde dehydrogenase Classification: OXIDOREDUCTASE Entry date in PDB: 2003-11-04 Resolution [Å]: 2.04 R-Factor: 0.196

CHAIN: A SWISS-PROT/TREMBL: P44801    KEYWORD: Complete proteome    Diaminopimelate biosynthesis    Lysine biosynthesis    NADP    Oxidoreductase    EC: 1.2.1.11 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Aspartate beta-semialdehyde dehydrogenase    Haemophilus influenzae SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Aspartate beta-semialdehyde dehydrogenase    Haemophilus influenzae SCOP: d.81.1.1 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    GAPDH-like    Aspartate beta-semialdehyde dehydrogenase    Haemophilus influenzae GO:  cytoplasm    aspartate-semialdehyde dehydrogenase activity    NAD binding    NADP binding    oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor    protein dimerization activity    amino acid biosynthesis    amino acid metabolism    lysine biosynthesis via diaminopimelate    CHAIN: B SWISS-PROT/TREMBL: P44801    KEYWORD: Complete proteome    Diaminopimelate biosynthesis    Lysine biosynthesis    NADP    Oxidoreductase    EC: 1.2.1.11 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Aspartate beta-semialdehyde dehydrogenase    Haemophilus influenzae SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Aspartate beta-semialdehyde dehydrogenase    Haemophilus influenzae SCOP: d.81.1.1 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    GAPDH-like    Aspartate beta-semialdehyde dehydrogenase    Haemophilus influenzae GO:  cytoplasm    aspartate-semialdehyde dehydrogenase activity    NAD binding    NADP binding    oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor    protein dimerization activity    amino acid biosynthesis    amino acid metabolism    lysine biosynthesis via diaminopimelate

Image Source: PDB

Loops in ArchDB40 clusters

1nwc_A_61 - HE => SUBCLASS : 2.3.6
1nwc_A_61 - HE => SUBCLASS : 2.3.7
1nwc_A_76 - HE => SUBCLASS : 3.1.10
1nwc_A_291 - HE => SUBCLASS : 3.4.2
1nwc_A_113 - HE => SUBCLASS : 3.6.1
1nwc_A_76 - HE => SUBCLASS : 3.6.4
1nwc_A_321 - HE => SUBCLASS : 4.11.1
1nwc_A_130 - EH => SUBCLASS : 1.1.4
1nwc_A_56 - EH => SUBCLASS : 3.1.1
1nwc_A_305 - EH => SUBCLASS : 3.8.2
1nwc_A_3 - EH => SUBCLASS : 4.14.1
1nwc_A_276 - EH => SUBCLASS : 5.12.1
1nwc_A_276 - EH => SUBCLASS : 5.12.3
1nwc_A_188 - HH => SUBCLASS : 5.4.1

Loops in ArchDB95 clusters

1nwc_A_108 - EH => SUBCLASS : 0.1.28
1nwc_A_56 - EH => SUBCLASS : 3.2.1
1nwc_A_56 - EH => SUBCLASS : 3.2.2
1nwc_A_305 - EH => SUBCLASS : 3.8.2
1nwc_A_305 - EH => SUBCLASS : 3.8.6
1nwc_A_3 - EH => SUBCLASS : 4.7.1
1nwc_A_276 - EH => SUBCLASS : 5.10.1
1nwc_A_94 - AR => SUBCLASS : 10.11.1
1nwc_A_188 - HH => SUBCLASS : 5.3.1
1nwc_A_61 - HE => SUBCLASS : 2.2.4
1nwc_A_61 - HE => SUBCLASS : 2.2.11
1nwc_A_136 - HE => SUBCLASS : 2.4.4
1nwc_A_113 - HE => SUBCLASS : 3.1.1
1nwc_A_76 - HE => SUBCLASS : 3.1.3
1nwc_A_76 - HE => SUBCLASS : 3.1.8
1nwc_A_291 - HE => SUBCLASS : 3.4.13
1nwc_A_291 - HE => SUBCLASS : 3.6.2
1nwc_A_12 - HE => SUBCLASS : 5.7.2

Loops in ArchDB-EC clusters

1nwc_A_188 - HH => SUBCLASS : 5.5.3

Loops not clustered in ArchDB

1nwc_A_264 - AR
1nwc_A_94 - AR
1nwc_A_264 - AR
1nwc_A_69 - EH
1nwc_A_154 - EH
1nwc_A_227 - EH
1nwc_A_341 - EH
1nwc_A_31 - HA
1nwc_A_330 - HA
1nwc_A_31 - HA
1nwc_A_330 - HA
1nwc_A_242 - HE
1nwc_A_198 - HE
1nwc_A_170 - HH
1nwc_A_312 - HH

1brm A - percentage of sequence identity: 72
1brm B - percentage of sequence identity: 72
1brm C - percentage of sequence identity: 72
1gl3 A - percentage of sequence identity: 72
1gl3 B - percentage of sequence identity: 72
1mb4 A - percentage of sequence identity: 69
1mb4 B - percentage of sequence identity: 69
1mc4 A - percentage of sequence identity: 69
1nwc A - percentage of sequence identity: 100
1nwc B - percentage of sequence identity: 100
1nwh A - percentage of sequence identity: 100
1nwh B - percentage of sequence identity: 100
1nx6 A - percentage of sequence identity: 100
1oza A - percentage of sequence identity: 99
1pqp A - percentage of sequence identity: 99
1pqu A - percentage of sequence identity: 99
1pqu B - percentage of sequence identity: 99
1pqu C - percentage of sequence identity: 99
1pqu D - percentage of sequence identity: 99
1pr3 A - percentage of sequence identity: 99
1ps8 A - percentage of sequence identity: 99
1pu2 A - percentage of sequence identity: 99
1q2x A - percentage of sequence identity: 99
1q2x B - percentage of sequence identity: 99
1t4b A - percentage of sequence identity: 71
1t4b B - percentage of sequence identity: 71
1t4d A - percentage of sequence identity: 71
1t4d B - percentage of sequence identity: 71
1t4d C - percentage of sequence identity: 71
1ta4 A - percentage of sequence identity: 100
1tb4 A - percentage of sequence identity: 100