PDB: 1ozh Compound: acetolactate synthase, catabolic Classification: LYASE Entry date in PDB: 2003-11-04 Resolution [Å]: 2.00 R-Factor: 0.191

CHAIN: A SWISS-PROT/TREMBL: P27696    KEYWORD: Transferase    EC: 2.2.1.6 SCOP: c.31.1.3 Alpha and beta proteins (a/b)    DHS-like NAD/FAD-binding domain    DHS-like NAD/FAD-binding domain    Pyruvate oxidase and decarboxylase, middle domain    Catabolic acetolactate synthase    Klebsiella pneumoniae SCOP: c.36.1.5 Alpha and beta proteins (a/b)    Thiamin diphosphate-binding fold (THDP-binding)    Thiamin diphosphate-binding fold (THDP-binding)    Pyruvate oxidase and decarboxylase Pyr module    Catabolic acetolactate synthase    Klebsiella pneumoniae SCOP: c.36.1.9 Alpha and beta proteins (a/b)    Thiamin diphosphate-binding fold (THDP-binding)    Thiamin diphosphate-binding fold (THDP-binding)    Pyruvate oxidase and decarboxylase PP module    Catabolic acetolactate synthase    Klebsiella pneumoniae GO:  acetolactate synthase activity    catalytic activity    thiamin pyrophosphate binding    branched chain family amino acid biosynthesis    CHAIN: B SWISS-PROT/TREMBL: P27696    KEYWORD: Transferase    EC: 2.2.1.6 SCOP: c.31.1.3 Alpha and beta proteins (a/b)    DHS-like NAD/FAD-binding domain    DHS-like NAD/FAD-binding domain    Pyruvate oxidase and decarboxylase, middle domain    Catabolic acetolactate synthase    Klebsiella pneumoniae SCOP: c.36.1.5 Alpha and beta proteins (a/b)    Thiamin diphosphate-binding fold (THDP-binding)    Thiamin diphosphate-binding fold (THDP-binding)    Pyruvate oxidase and decarboxylase Pyr module    Catabolic acetolactate synthase    Klebsiella pneumoniae SCOP: c.36.1.9 Alpha and beta proteins (a/b)    Thiamin diphosphate-binding fold (THDP-binding)    Thiamin diphosphate-binding fold (THDP-binding)    Pyruvate oxidase and decarboxylase PP module    Catabolic acetolactate synthase    Klebsiella pneumoniae GO:  acetolactate synthase activity    catalytic activity    thiamin pyrophosphate binding    branched chain family amino acid biosynthesis    CHAIN: C SWISS-PROT/TREMBL: P27696    KEYWORD: Transferase    EC: 2.2.1.6 SCOP: c.31.1.3 Alpha and beta proteins (a/b)    DHS-like NAD/FAD-binding domain    DHS-like NAD/FAD-binding domain    Pyruvate oxidase and decarboxylase, middle domain    Catabolic acetolactate synthase    Klebsiella pneumoniae SCOP: c.36.1.5 Alpha and beta proteins (a/b)    Thiamin diphosphate-binding fold (THDP-binding)    Thiamin diphosphate-binding fold (THDP-binding)    Pyruvate oxidase and decarboxylase Pyr module    Catabolic acetolactate synthase    Klebsiella pneumoniae SCOP: c.36.1.9 Alpha and beta proteins (a/b)    Thiamin diphosphate-binding fold (THDP-binding)    Thiamin diphosphate-binding fold (THDP-binding)    Pyruvate oxidase and decarboxylase PP module    Catabolic acetolactate synthase    Klebsiella pneumoniae GO:  acetolactate synthase activity    catalytic activity    thiamin pyrophosphate binding    branched chain family amino acid biosynthesis    CHAIN: D SWISS-PROT/TREMBL: P27696    KEYWORD: Transferase    EC: 2.2.1.6 SCOP: c.31.1.3 Alpha and beta proteins (a/b)    DHS-like NAD/FAD-binding domain    DHS-like NAD/FAD-binding domain    Pyruvate oxidase and decarboxylase, middle domain    Catabolic acetolactate synthase    Klebsiella pneumoniae SCOP: c.36.1.5 Alpha and beta proteins (a/b)    Thiamin diphosphate-binding fold (THDP-binding)    Thiamin diphosphate-binding fold (THDP-binding)    Pyruvate oxidase and decarboxylase Pyr module    Catabolic acetolactate synthase    Klebsiella pneumoniae SCOP: c.36.1.9 Alpha and beta proteins (a/b)    Thiamin diphosphate-binding fold (THDP-binding)    Thiamin diphosphate-binding fold (THDP-binding)    Pyruvate oxidase and decarboxylase PP module    Catabolic acetolactate synthase    Klebsiella pneumoniae GO:  acetolactate synthase activity    catalytic activity    thiamin pyrophosphate binding    branched chain family amino acid biosynthesis

Image Source: PDB

Loops in ArchDB40 clusters

1ozh_A_8 - EH => SUBCLASS : 2.1.1
1ozh_A_50 - EH => SUBCLASS : 2.1.2
1ozh_A_511 - EH => SUBCLASS : 2.1.27
1ozh_A_318 - EH => SUBCLASS : 2.5.1
1ozh_A_511 - EH => SUBCLASS : 3.12.1
1ozh_A_134 - EH => SUBCLASS : 3.12.1
1ozh_A_75 - EH => SUBCLASS : 3.14.1
1ozh_A_388 - EH => SUBCLASS : 3.26.1
1ozh_A_467 - EH => SUBCLASS : 4.46.1

Loops in ArchDB95 clusters

1ozh_A_8 - EH => SUBCLASS : 2.1.1
1ozh_A_50 - EH => SUBCLASS : 2.1.3
1ozh_A_511 - EH => SUBCLASS : 2.1.19
1ozh_A_134 - EH => SUBCLASS : 2.1.19
1ozh_A_318 - EH => SUBCLASS : 2.5.2
1ozh_A_318 - EH => SUBCLASS : 2.5.3
1ozh_A_134 - EH => SUBCLASS : 3.10.1
1ozh_A_511 - EH => SUBCLASS : 3.10.1
1ozh_A_388 - EH => SUBCLASS : 3.12.1
1ozh_A_75 - EH => SUBCLASS : 3.12.3
1ozh_A_467 - EH => SUBCLASS : 4.60.1
1ozh_A_456 - HE => SUBCLASS : 2.1.1
1ozh_A_89 - HE => SUBCLASS : 2.1.1
1ozh_A_224 - HE => SUBCLASS : 2.1.2
1ozh_A_57 - HE => SUBCLASS : 2.1.2
1ozh_A_501 - HE => SUBCLASS : 2.1.14
1ozh_A_267 - HE => SUBCLASS : 2.2.1
1ozh_A_194 - HE => SUBCLASS : 2.2.1
1ozh_A_267 - HE => SUBCLASS : 2.2.6
1ozh_A_169 - HE => SUBCLASS : 2.13.1
1ozh_A_13 - HE => SUBCLASS : 3.1.1
1ozh_A_57 - HE => SUBCLASS : 3.2.7
1ozh_A_13 - HE => SUBCLASS : 3.3.1
1ozh_A_425 - HE => SUBCLASS : 3.4.3
1ozh_A_224 - HE => SUBCLASS : 3.5.4
1ozh_A_38 - HE => SUBCLASS : 3.15.1
1ozh_A_373 - HE => SUBCLASS : 4.13.1

Loops in ArchDB-EC clusters

1ozh_A_373 - HE => SUBCLASS : 4.41.1

Loops not clustered in ArchDB

1ozh_A_28 - EH
1ozh_A_535 - EH
1ozh_A_440 - EH
1ozh_A_412 - EH
1ozh_A_256 - EH
1ozh_A_210 - EH
1ozh_A_176 - EH
1ozh_A_162 - EH
1ozh_A_102 - EH
1ozh_A_277 - HA
1ozh_A_238 - HA
1ozh_A_299 - HA
1ozh_A_277 - HA
1ozh_A_238 - HA
1ozh_A_299 - HA
1ozh_A_124 - HE
1ozh_A_144 - HE
1ozh_A_396 - HE
1ozh_A_521 - HE
1ozh_A_83 - HH
1ozh_A_478 - HH
1ozh_A_447 - HH
1ozh_A_343 - HH
1ozh_A_324 - HH

1ozf A - percentage of sequence identity: 100
1ozf B - percentage of sequence identity: 100
1ozg A - percentage of sequence identity: 100
1ozg B - percentage of sequence identity: 100
1ozh A - percentage of sequence identity: 100
1ozh B - percentage of sequence identity: 100
1ozh C - percentage of sequence identity: 100
1ozh D - percentage of sequence identity: 100