PDB: 1qki Compound: glucose-6-phosphate 1-dehydrogenase Classification: OXIDOREDUCTASE (CHOH(D)-NADP) Entry date in PDB: 2000-03-16 Resolution [Å]: 3.00 R-Factor: 0.247

CHAIN: A SWISS-PROT/TREMBL: P11413    KEYWORD: 3D-structure    Acetylation    Alternative splicing    Disease mutation    Glucose metabolism    Hereditary hemolytic anemia    NADP    Oxidoreductase    Polymorphism    EC: 1.1.1.49 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glucose 6-phosphate dehydrogenase, N-terminal domain    Human (Homo sapiens) SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glucose 6-phosphate dehydrogenase, N-terminal domain    Human (Homo sapiens) SCOP: d.81.1.5 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glucose 6-phosphate dehydrogenase-like    Glucose 6-phosphate dehydrogenase    Human (Homo sapiens) SCOP: d.81.1.5 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glucose 6-phosphate dehydrogenase-like    Glucose 6-phosphate dehydrogenase    Human (Homo sapiens) GO:  glucose-6-phosphate 1-dehydrogenase activity    glucose metabolism    CHAIN: B SWISS-PROT/TREMBL: P11413    KEYWORD: 3D-structure    Acetylation    Alternative splicing    Disease mutation    Glucose metabolism    Hereditary hemolytic anemia    NADP    Oxidoreductase    Polymorphism    EC: 1.1.1.49 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glucose 6-phosphate dehydrogenase, N-terminal domain    Human (Homo sapiens) SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glucose 6-phosphate dehydrogenase, N-terminal domain    Human (Homo sapiens) SCOP: d.81.1.5 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glucose 6-phosphate dehydrogenase-like    Glucose 6-phosphate dehydrogenase    Human (Homo sapiens) SCOP: d.81.1.5 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glucose 6-phosphate dehydrogenase-like    Glucose 6-phosphate dehydrogenase    Human (Homo sapiens) GO:  glucose-6-phosphate 1-dehydrogenase activity    glucose metabolism    CHAIN: C SWISS-PROT/TREMBL: P11413    KEYWORD: 3D-structure    Acetylation    Alternative splicing    Disease mutation    Glucose metabolism    Hereditary hemolytic anemia    NADP    Oxidoreductase    Polymorphism    EC: 1.1.1.49 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glucose 6-phosphate dehydrogenase, N-terminal domain    Human (Homo sapiens) SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glucose 6-phosphate dehydrogenase, N-terminal domain    Human (Homo sapiens) SCOP: d.81.1.5 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glucose 6-phosphate dehydrogenase-like    Glucose 6-phosphate dehydrogenase    Human (Homo sapiens) SCOP: d.81.1.5 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glucose 6-phosphate dehydrogenase-like    Glucose 6-phosphate dehydrogenase    Human (Homo sapiens) GO:  glucose-6-phosphate 1-dehydrogenase activity    glucose metabolism    CHAIN: D SWISS-PROT/TREMBL: P11413    KEYWORD: 3D-structure    Acetylation    Alternative splicing    Disease mutation    Glucose metabolism    Hereditary hemolytic anemia    NADP    Oxidoreductase    Polymorphism    EC: 1.1.1.49 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glucose 6-phosphate dehydrogenase, N-terminal domain    Human (Homo sapiens) SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glucose 6-phosphate dehydrogenase, N-terminal domain    Human (Homo sapiens) SCOP: d.81.1.5 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glucose 6-phosphate dehydrogenase-like    Glucose 6-phosphate dehydrogenase    Human (Homo sapiens) SCOP: d.81.1.5 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glucose 6-phosphate dehydrogenase-like    Glucose 6-phosphate dehydrogenase    Human (Homo sapiens) GO:  glucose-6-phosphate 1-dehydrogenase activity    glucose metabolism    CHAIN: E SWISS-PROT/TREMBL: P11413    KEYWORD: 3D-structure    Acetylation    Alternative splicing    Disease mutation    Glucose metabolism    Hereditary hemolytic anemia    NADP    Oxidoreductase    Polymorphism    EC: 1.1.1.49 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glucose 6-phosphate dehydrogenase, N-terminal domain    Human (Homo sapiens) SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glucose 6-phosphate dehydrogenase, N-terminal domain    Human (Homo sapiens) SCOP: d.81.1.5 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glucose 6-phosphate dehydrogenase-like    Glucose 6-phosphate dehydrogenase    Human (Homo sapiens) SCOP: d.81.1.5 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glucose 6-phosphate dehydrogenase-like    Glucose 6-phosphate dehydrogenase    Human (Homo sapiens) GO:  glucose-6-phosphate 1-dehydrogenase activity    glucose metabolism    CHAIN: F SWISS-PROT/TREMBL: P11413    KEYWORD: 3D-structure    Acetylation    Alternative splicing    Disease mutation    Glucose metabolism    Hereditary hemolytic anemia    NADP    Oxidoreductase    Polymorphism    EC: 1.1.1.49 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glucose 6-phosphate dehydrogenase, N-terminal domain    Human (Homo sapiens) SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glucose 6-phosphate dehydrogenase, N-terminal domain    Human (Homo sapiens) SCOP: d.81.1.5 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glucose 6-phosphate dehydrogenase-like    Glucose 6-phosphate dehydrogenase    Human (Homo sapiens) SCOP: d.81.1.5 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glucose 6-phosphate dehydrogenase-like    Glucose 6-phosphate dehydrogenase    Human (Homo sapiens) GO:  glucose-6-phosphate 1-dehydrogenase activity    glucose metabolism    CHAIN: G SWISS-PROT/TREMBL: P11413    KEYWORD: 3D-structure    Acetylation    Alternative splicing    Disease mutation    Glucose metabolism    Hereditary hemolytic anemia    NADP    Oxidoreductase    Polymorphism    EC: 1.1.1.49 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glucose 6-phosphate dehydrogenase, N-terminal domain    Human (Homo sapiens) SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glucose 6-phosphate dehydrogenase, N-terminal domain    Human (Homo sapiens) SCOP: d.81.1.5 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glucose 6-phosphate dehydrogenase-like    Glucose 6-phosphate dehydrogenase    Human (Homo sapiens) SCOP: d.81.1.5 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glucose 6-phosphate dehydrogenase-like    Glucose 6-phosphate dehydrogenase    Human (Homo sapiens) GO:  glucose-6-phosphate 1-dehydrogenase activity    glucose metabolism    CHAIN: H SWISS-PROT/TREMBL: P11413    KEYWORD: 3D-structure    Acetylation    Alternative splicing    Disease mutation    Glucose metabolism    Hereditary hemolytic anemia    NADP    Oxidoreductase    Polymorphism    EC: 1.1.1.49 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glucose 6-phosphate dehydrogenase, N-terminal domain    Human (Homo sapiens) SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glucose 6-phosphate dehydrogenase, N-terminal domain    Human (Homo sapiens) SCOP: d.81.1.5 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glucose 6-phosphate dehydrogenase-like    Glucose 6-phosphate dehydrogenase    Human (Homo sapiens) SCOP: d.81.1.5 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glucose 6-phosphate dehydrogenase-like    Glucose 6-phosphate dehydrogenase    Human (Homo sapiens) GO:  glucose-6-phosphate 1-dehydrogenase activity    glucose metabolism

Image Source: PDB

Loops in ArchDB-EC clusters

1qki_A_436 - HH => SUBCLASS : 8.14.1

Loops not clustered in ArchDB

1qki_A_353 - AR
1qki_A_32 - EH
1qki_A_480 - EH
1qki_A_415 - EH
1qki_A_230 - EH
1qki_A_196 - EH
1qki_A_165 - EH
1qki_A_135 - EH
1qki_A_105 - EH
1qki_A_65 - EH
1qki_A_389 - HA
1qki_A_366 - HA
1qki_A_337 - HA
1qki_A_303 - HA
1qki_A_399 - HA
1qki_A_281 - HE
1qki_A_48 - HE
1qki_A_95 - HE
1qki_A_115 - HE
1qki_A_144 - HE
1qki_A_177 - HE
1qki_A_206 - HE
1qki_A_455 - HE
1qki_A_263 - HH
1qki_A_254 - HH
1qki_A_247 - HH
1qki_A_78 - HH
1qki_A_42 - HH
1qki_A_424 - HH

1qki A - percentage of sequence identity: 100
1qki B - percentage of sequence identity: 100
1qki C - percentage of sequence identity: 100
1qki D - percentage of sequence identity: 100
1qki E - percentage of sequence identity: 100
1qki F - percentage of sequence identity: 100
1qki G - percentage of sequence identity: 100
1qki H - percentage of sequence identity: 100
2bh9 A - percentage of sequence identity: 99
2bhl A - percentage of sequence identity: 99
2bhl B - percentage of sequence identity: 99