PDB: 2pva Compound: penicillin v acylase Classification: HYDROLASE Entry date in PDB: 2000-07-26 Resolution [Å]: 2.50 R-Factor: 0.196

CHAIN: A SWISS-PROT/TREMBL: P12256    KEYWORD: 3D-structure    Antibiotic resistance    Hydrolase    EC: 3.5.1.11 SCOP: d.153.1.3 Alpha and beta proteins (a+b)    Ntn hydrolase-like    N-terminal nucleophile aminohydrolases (Ntn hydrolases)    Penicillin V acylase    Penicillin V acylase    Bacillus sphaericus GO:   CHAIN: B SWISS-PROT/TREMBL: P12256    KEYWORD: 3D-structure    Antibiotic resistance    Hydrolase    EC: 3.5.1.11 SCOP: d.153.1.3 Alpha and beta proteins (a+b)    Ntn hydrolase-like    N-terminal nucleophile aminohydrolases (Ntn hydrolases)    Penicillin V acylase    Penicillin V acylase    Bacillus sphaericus GO:   CHAIN: C SWISS-PROT/TREMBL: P12256    KEYWORD: 3D-structure    Antibiotic resistance    Hydrolase    EC: 3.5.1.11 SCOP: d.153.1.3 Alpha and beta proteins (a+b)    Ntn hydrolase-like    N-terminal nucleophile aminohydrolases (Ntn hydrolases)    Penicillin V acylase    Penicillin V acylase    Bacillus sphaericus GO:   CHAIN: D SWISS-PROT/TREMBL: P12256    KEYWORD: 3D-structure    Antibiotic resistance    Hydrolase    EC: 3.5.1.11 SCOP: d.153.1.3 Alpha and beta proteins (a+b)    Ntn hydrolase-like    N-terminal nucleophile aminohydrolases (Ntn hydrolases)    Penicillin V acylase    Penicillin V acylase    Bacillus sphaericus GO:

Image Source: PDB

Loops in ArchDB40 clusters

2pva_A_116 - HE => SUBCLASS : 0.1.4
2pva_A_116 - HE => SUBCLASS : 0.1.13
2pva_A_116 - HE => SUBCLASS : 0.1.27
2pva_A_153 - HA => SUBCLASS : 2.2.2
2pva_A_288 - HA => SUBCLASS : 2.2.4
2pva_A_200 - HA => SUBCLASS : 2.3.1
2pva_A_142 - HA => SUBCLASS : 3.1.1
2pva_A_3 - HA => SUBCLASS : 3.1.1
2pva_A_275 - HA => SUBCLASS : 4.1.1
2pva_A_69 - HA => SUBCLASS : 4.2.1
2pva_A_38 - HA => SUBCLASS : 6.6.1
2pva_A_98 - EH => SUBCLASS : 1.3.2
2pva_A_66 - AR => SUBCLASS : 1.1.4
2pva_A_47 - AR => SUBCLASS : 2.1.2

Loops in ArchDB95 clusters

2pva_A_98 - EH => SUBCLASS : 1.1.12
2pva_A_98 - EH => SUBCLASS : 1.1.22
2pva_A_66 - AR => SUBCLASS : 1.2.2
2pva_A_47 - AR => SUBCLASS : 3.13.1
2pva_A_47 - AR => SUBCLASS : 5.18.1
2pva_A_105 - HH => SUBCLASS : 3.6.2
2pva_A_116 - HE => SUBCLASS : 0.1.2
2pva_A_116 - HE => SUBCLASS : 0.1.8
2pva_A_153 - HA => SUBCLASS : 2.2.2
2pva_A_288 - HA => SUBCLASS : 2.2.4
2pva_A_200 - HA => SUBCLASS : 2.3.1
2pva_A_3 - HA => SUBCLASS : 3.1.1
2pva_A_142 - HA => SUBCLASS : 3.1.1
2pva_A_69 - HA => SUBCLASS : 3.1.2
2pva_A_275 - HA => SUBCLASS : 4.1.1
2pva_A_38 - HA => SUBCLASS : 6.4.1

Loops in ArchDB-EC clusters

2pva_A_116 - HE => SUBCLASS : 0.1.14

Loops not clustered in ArchDB

2pva_A_296 - AR
2pva_A_296 - AR
2pva_A_13 - AR
2pva_A_28 - AR
2pva_A_47 - AR
2pva_A_66 - AR
2pva_A_77 - AR
2pva_A_126 - AR
2pva_A_162 - AR
2pva_A_162 - AR
2pva_A_126 - AR
2pva_A_77 - AR
2pva_A_28 - AR
2pva_A_13 - AR
2pva_A_205 - EH
2pva_A_172 - EH
2pva_A_38 - HA
2pva_A_288 - HA
2pva_A_275 - HA
2pva_A_200 - HA
2pva_A_3 - HA
2pva_A_153 - HA
2pva_A_142 - HA
2pva_A_54 - HA
2pva_A_54 - HA
2pva_A_69 - HA
2pva_A_179 - HE
2pva_A_245 - HE
2pva_A_225 - HH

2pva A - percentage of sequence identity: 100
2pva B - percentage of sequence identity: 100
2pva C - percentage of sequence identity: 100
2pva D - percentage of sequence identity: 100
3pva A - percentage of sequence identity: 97
3pva B - percentage of sequence identity: 97
3pva C - percentage of sequence identity: 97
3pva D - percentage of sequence identity: 97
3pva E - percentage of sequence identity: 97
3pva F - percentage of sequence identity: 97
3pva G - percentage of sequence identity: 97
3pva H - percentage of sequence identity: 97