PDB: 3lad Compound: Dihydrolipoamide dehydrogenase Classification: OXIDOREDUCTASE Entry date in PDB: 1994-01-31 Resolution [Å]: 2.20 R-Factor: 0.192

CHAIN: A SWISS-PROT/TREMBL: P18925    KEYWORD: 3D-structure    FAD    Flavoprotein    Glycolysis    NAD    Oxidoreductase    Redox-active center    EC: 1.8.1.4 SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Dihydrolipoamide dehydrogenase    Azotobacter vinelandii SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Dihydrolipoamide dehydrogenase    Azotobacter vinelandii SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Dihydrolipoamide dehydrogenase    Azotobacter vinelandii SCOP: d.87.1.1 Alpha and beta proteins (a+b)    CO dehydrogenase flavoprotein C-domain-like    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    Dihydrolipoamide dehydrogenase    Azotobacter vinelandii GO:  cytoplasm    dihydrolipoyl dehydrogenase activity    disulfide oxidoreductase activity    FAD binding    oxidoreductase activity    electron transport    metabolism    CHAIN: B SWISS-PROT/TREMBL: P18925    KEYWORD: 3D-structure    FAD    Flavoprotein    Glycolysis    NAD    Oxidoreductase    Redox-active center    EC: 1.8.1.4 SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Dihydrolipoamide dehydrogenase    Azotobacter vinelandii SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Dihydrolipoamide dehydrogenase    Azotobacter vinelandii SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Dihydrolipoamide dehydrogenase    Azotobacter vinelandii SCOP: d.87.1.1 Alpha and beta proteins (a+b)    CO dehydrogenase flavoprotein C-domain-like    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    Dihydrolipoamide dehydrogenase    Azotobacter vinelandii GO:  cytoplasm    dihydrolipoyl dehydrogenase activity    disulfide oxidoreductase activity    FAD binding    oxidoreductase activity    electron transport    metabolism

Image Source: PDB

Loops in ArchDB40 clusters

3lad_A_120 - HA => SUBCLASS : 2.1.1
3lad_A_129 - HA => SUBCLASS : 3.1.1
3lad_A_401 - HA => SUBCLASS : 4.1.2
3lad_A_120 - HA => SUBCLASS : 4.5.1
3lad_A_182 - EH => SUBCLASS : 3.2.1
3lad_A_413 - EH => SUBCLASS : 3.20.1
3lad_A_379 - EH => SUBCLASS : 4.22.1
3lad_A_205 - EH => SUBCLASS : 10.3.1
3lad_A_236 - AR => SUBCLASS : 1.2.1
3lad_A_115 - AR => SUBCLASS : 1.3.2
3lad_A_236 - AR => SUBCLASS : 2.2.3
3lad_A_271 - AR => SUBCLASS : 2.4.2
3lad_A_138 - AR => SUBCLASS : 3.10.1
3lad_A_146 - AR => SUBCLASS : 3.11.2
3lad_A_423 - HH => SUBCLASS : 3.1.1

Loops in ArchDB95 clusters

3lad_A_182 - EH => SUBCLASS : 3.5.1
3lad_A_413 - EH => SUBCLASS : 3.11.1
3lad_A_379 - EH => SUBCLASS : 4.16.1
3lad_A_205 - EH => SUBCLASS : 10.2.1
3lad_A_236 - AR => SUBCLASS : 1.1.4
3lad_A_115 - AR => SUBCLASS : 1.3.2
3lad_A_236 - AR => SUBCLASS : 2.5.2
3lad_A_138 - AR => SUBCLASS : 3.13.1
3lad_A_146 - AR => SUBCLASS : 3.15.2
3lad_A_138 - AR => SUBCLASS : 5.18.1
3lad_A_423 - HH => SUBCLASS : 3.1.1
3lad_A_87 - HE => SUBCLASS : 1.1.1
3lad_A_190 - HE => SUBCLASS : 1.1.1
3lad_A_221 - HE => SUBCLASS : 1.2.1
3lad_A_13 - HE => SUBCLASS : 2.1.1
3lad_A_369 - HE => SUBCLASS : 2.1.1
3lad_A_129 - HA => SUBCLASS : 3.1.1
3lad_A_120 - HA => SUBCLASS : 3.2.1
3lad_A_243 - HA => SUBCLASS : 3.31.1
3lad_A_401 - HA => SUBCLASS : 4.1.2
3lad_A_401 - HA => SUBCLASS : 5.5.1

Loops in ArchDB-EC clusters

3lad_A_440 - HH => SUBCLASS : 7.3.2

Loops not clustered in ArchDB

3lad_A_138 - AR
3lad_A_263 - AR
3lad_A_263 - AR
3lad_A_271 - AR
3lad_A_278 - AR
3lad_A_278 - AR
3lad_A_236 - AR
3lad_A_115 - AR
3lad_A_152 - AR
3lad_A_146 - AR
3lad_A_152 - AR
3lad_A_6 - EH
3lad_A_361 - EH
3lad_A_313 - EH
3lad_A_167 - EH
3lad_A_29 - EH
3lad_A_243 - HA
3lad_A_354 - HA
3lad_A_254 - HA
3lad_A_129 - HA
3lad_A_401 - HA
3lad_A_254 - HA
3lad_A_354 - HA
3lad_A_120 - HA
3lad_A_390 - HE
3lad_A_326 - HE
3lad_A_170 - HE
3lad_A_53 - HH
3lad_A_46 - HH

1lpf A - percentage of sequence identity: 84
1lpf B - percentage of sequence identity: 84
3lad A - percentage of sequence identity: 100
3lad B - percentage of sequence identity: 100