PDB: 6pax Compound: homeobox protein pax-6 Classification: GENE REGULATION/DNA Entry date in PDB: 1999-07-13 Resolution [Å]: 2.50 R-Factor: 0.233

CHAIN: A SWISS-PROT/TREMBL: P26367    KEYWORD: 3D-structure    Alternative splicing    Developmental protein    Differentiation    Disease mutation    DNA-binding    Homeobox    Nuclear protein    Paired box    Repressor    Transcription regulation    SCOP: a.4.1.5 All alpha proteins    DNA/RNA-binding 3-helical bundle    Homeodomain-like    Paired domain    Pax-6    Human (Homo sapiens) SCOP: a.4.1.5 All alpha proteins    DNA/RNA-binding 3-helical bundle    Homeodomain-like    Paired domain    Pax-6    Human (Homo sapiens) GO:  nucleus    DNA binding    transcription factor activity    development    regulation of transcription    regulation of transcription, DNA-dependent

Image Source: PDB

Loops in ArchDB40 clusters

6pax_A_3 - HA => SUBCLASS : 3.1.1
6pax_A_36 - HH => SUBCLASS : 3.1.1
6pax_A_20 - HH => SUBCLASS : 3.3.1
6pax_A_78 - HH => SUBCLASS : 5.2.1
6pax_A_78 - HH => SUBCLASS : 5.2.2

Loops in ArchDB95 clusters

6pax_A_36 - HH => SUBCLASS : 3.1.1
6pax_A_20 - HH => SUBCLASS : 3.2.1
6pax_A_78 - HH => SUBCLASS : 5.2.1
6pax_A_96 - HH => SUBCLASS : 10.18.1
6pax_A_3 - HA => SUBCLASS : 3.1.1

Loops not clustered in ArchDB

6pax_A_11 - EH
6pax_A_47 - HH

1k78 E - percentage of sequence identity: 77
1k78 I - percentage of sequence identity: 77
1mdm A - percentage of sequence identity: 77