ArchDB - Biological DataBase of Protein Loops

Grup de Recerca en Informàtica Biomèdica

Information on SUBCLASS 6.5.1

Subclass Accession number: 7974
Subclass: 6.5.1

PSSM

Type: HA beta-beta hairpin
DB: ArchDB-EC

Image coordinates:

Rasmol PDB

Jmol PDB

Consensus coordinates:

Rasmol PDB

Jmol PDB

Number of loops: 9

Average sequence ID (%) : 32.5 +/- 30.5
Average RMSD (Å) : 0.833 +/- 0.583

Consensus geometry

d (Å): 5

delta (°): 90-135

theta (°): 135-180

rho (°): 315-360

Consensus Sequence:	XXXpXpXpXX
(φψ)-conformation:	bbapaababb

Pattern:	[LVW]	[ACG]	[fhy]	[ITW]	[CMPT]	[DENS]	[EPS]	[DENQRST]	[iklv]	[rst]	[rtwy]	[dep]	[ilty]	x
Conservation:	1.602	1.434	-0.182	0.011	-0.464	0.945	1.322	-0.427	-1.429	-0.669	-0.677	-0.352	-1.112	-1.000

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1i71_A_60	1i71	A	60	72	WCYTMDPSVRWEY.	EEEBSSTT--EEE.	bbxbaxaababbx.
1ki0_A_144	1ki0	A	144	156	WCYTTDPEKRYDY.	EEEBS-TT-SEEE.	bbxbaxaababbx.
1ki0_A_225	1ki0	A	225	237	WCFTTDPNKRWEL.	EEEBS-TT-SEEE.	bbxbaxaababbx.
1ki0_A_315	1ki0	A	315	327	WCHTTNSQVRWEY.	EEEBSSTT-SEEE.	bbxbaxaababbx.
1nl1_A_126	1nl1	A	126	138	WCYTTSPTLRREE.	EEEBSSTT--EEE.	bbxbaxaababbx.
1qla_A_562	1qla	A	565	578	LASWPNPEQTLPTL	EEE--STT-SS-EE	bbbbabaaxabxxb
2occ_F_55	2occ	F	58	71	VGCICEEDNSTVIW	EEE--STT-SS-EE	bbbxabaaxabxxb
3kiv_*_62	3kiv	-	62	74	WCFTTDPSIRWEY.	EEEBSSTT--EEE.	bbxbaxaababbx.
5hpg_A_62	5hpg	A	62	74	WCYTTNPRKLYDY.	EEEBS-TT--EEE.	bbxbaxaababbx.

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1ki0_A_144	1ki0	A	BCNBICINE	W - 144
1ki0_A_144	1ki0	A	BCNBICINE	Y - 146
1ki0_A_144	1ki0	A	BCNBICINE	R - 153
1ki0_A_144	1ki0	A	BCNBICINE	Y - 154
1ki0_A_144	1ki0	A	BCNBICINE	Y - 156
1ki0_A_225	1ki0	A	BCNBICINE	W - 225
1ki0_A_225	1ki0	A	BCNBICINE	F - 227
1ki0_A_225	1ki0	A	BCNBICINE	R - 234
1ki0_A_225	1ki0	A	BCNBICINE	W - 235
1ki0_A_315	1ki0	A	BCNBICINE	W - 315
1ki0_A_315	1ki0	A	BCNBICINE	H - 317
1ki0_A_315	1ki0	A	BCNBICINE	R - 324
1ki0_A_315	1ki0	A	BCNBICINE	W - 325
2occ_F_55	2occ	F	ZNZINC ION	C - 60
2occ_F_55	2occ	F	ZNZINC ION	I - 61
2occ_F_55	2occ	F	ZNZINC ION	C - 62
2occ_F_55	2occ	F	ZNZINC ION	I - 70
2occ_F_55	2occ	F	ZNZINC ION	F - 72
3kiv_*_62	3kiv	*	ACA6-AMINOHEXANOIC ACID	W - 62
3kiv_*_62	3kiv	*	ACA6-AMINOHEXANOIC ACID	F - 64
3kiv_*_62	3kiv	*	ACA6-AMINOHEXANOIC ACID	R - 71
3kiv_*_62	3kiv	*	ACA6-AMINOHEXANOIC ACID	W - 72
3kiv_*_62	3kiv	*	ACA6-AMINOHEXANOIC ACID	Y - 74

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
3kiv_*_62	3kiv	*	LBSLYSINE BINDING SITE	W - 62
3kiv_*_62	3kiv	*	LBSLYSINE BINDING SITE	R - 71
3kiv_*_62	3kiv	*	LBSLYSINE BINDING SITE	W - 72

Clusters included in this Subclass

CLUSTER: HA.8.1