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Information on SUBCLASS 4.22.2
Subclass Accession number: 8483
Subclass: 4.22.2 PSSM
Type: HE alpha-beta
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 1 (>75 %)  2.1 (>75 %)  2.1.1 (>75 %)  2.1.1.77
GO : GO:0008168 (>75 %)  GO:0008171 (>75 %)  GO:0008276 (>75 %)  GO:0008757 (>75 %)  GO:0016741 (>75 %)  
SCOP : 53334 (>75 %)  53335 (>75 %)  53354 (>75 %)  
 Number of loops: 4

Average sequence ID (%) : 18.4 +/- 16.6
Average RMSD (Å) : 0.375 +/- 0.050

Consensus geometry
d (Å): 9 delta (°): 90-135 theta (°): 135-180 rho (°): 45-90
Consensus Sequence: XhGXphXh
(φψ)-conformation: aaeaapbb
Pattern: xx[ASTV]x[CLVY][FMV]x[RTW]x[IV][G]x[EKT][GM]x[IV][IKV][AGS]x
Conservation:-1.270-1.150-0.268-0.277-0.3880.292-0.589-0.346-0.2281.3572.898-0.7890.1450.522-0.9491.357-0.1330.246-0.428
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1dl5_A_881dl5   A88106YNAAVMSRVVGEKGLVVSVHHHHHHHHHH-TT-EEEEEaaaaaaaaaaeaaxbbbbb
1ej0_A_641ej0   A6482GWSQYVVTQIGGKGRIIACHHHHHHHHHH-TT-EEEEEaaaaaaaaaaeaaxbbbbb
1i1n_A_901i1n   A90108ILTACFARMVGCTGKVIGIHHHHHHHHHH-TT-EEEEEaaaaaaaaaaeaaxbbbbb
1o0y_A_1911o0y   A192210EDVHLMKWIVGDEMGVKASHHHHHHHHHH-TTSEEEEEaaaaaaaaaaeaabxbbxb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1dl5_A_881dl5   A     SAHS-ADENOSYL-L-HOMOCYSTEINE Y - 88
1dl5_A_881dl5   A     SAHS-ADENOSYL-L-HOMOCYSTEINE N - 89
1dl5_A_881dl5   A     SAHS-ADENOSYL-L-HOMOCYSTEINE A - 90
1dl5_A_881dl5   A     SAHS-ADENOSYL-L-HOMOCYSTEINE S - 105
1dl5_A_881dl5   A     SAHS-ADENOSYL-L-HOMOCYSTEINE V - 106
1dl5_A_881dl5   A     SAHS-ADENOSYL-L-HOMOCYSTEINE E - 107
1ej0_A_641ej0   A     SAMS-ADENOSYLMETHIONINE G - 64
1ej0_A_641ej0   A     SAMS-ADENOSYLMETHIONINE W - 65
1ej0_A_641ej0   A     SAMS-ADENOSYLMETHIONINE S - 66
1ej0_A_641ej0   A     HGMERCURY (II) ION A - 81
1ej0_A_641ej0   A     HGMERCURY (II) ION C - 82
1ej0_A_641ej0   A     SAMS-ADENOSYLMETHIONINE C - 82
1ej0_A_641ej0   A     HGMERCURY (II) ION D - 83
1ej0_A_641ej0   A     SAMS-ADENOSYLMETHIONINE D - 83
1i1n_A_901i1n   A     SAHS-ADENOSYL-L-HOMOCYSTEINE I - 90
1i1n_A_901i1n   A     SAHS-ADENOSYL-L-HOMOCYSTEINE L - 91
1i1n_A_901i1n   A     SAHS-ADENOSYL-L-HOMOCYSTEINE I - 108
1i1n_A_901i1n   A     SAHS-ADENOSYL-L-HOMOCYSTEINE D - 109

Clusters included in this Subclass
CLUSTER: HE.5.136