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Information on SUBCLASS 8.7.1
Subclass Accession number: 828
Subclass: 8.7.1 PSSM
Type: HA beta-beta hairpin
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 3.2 (>75 %)  3.2.2 (>50 %)  3.2.2.223.4 (>75 %)  3.4.21 (>75 %)  
GO : GO:0004175 (>50 %)  GO:0004252 (>50 %)  GO:0004872 (>75 %)  GO:0005509 (>50 %)  GO:0005515 (>75 %)  GO:0005529 (>50 %)  GO:0008233 (>50 %)  GO:0008236 (>50 %)  GO:0016798 (>50 %)  GO:0016799 (>50 %)  GO:0030246 (>50 %)  GO:0030597 (>50 %)  
SCOP : 50352 (>75 %)  50370 (>75 %)  50371 (>75 %)  50493 (>75 %)  50494 (>75 %)  50514 (>75 %)  57585 (>75 %)  57586 (>75 %)  57587 (>75 %)  
 Number of loops: 3

Average sequence ID (%) : 61.3 +/- -9.5
Average RMSD (Å) : 0.367 +/- 0.058

Consensus geometry
d (Å): 5 delta (°): 90-135 theta (°): 90-135 rho (°): 270-315
Consensus Sequence: SWGpGCAXXcph
(φψ)-conformation: abepeblpplbb
Pattern: [RT][MWY][FTY][LV][T][G][I][V][S][W][G][EQR][G][C][A]x[KV][DG][HK][FPY][G][IV][Y][T][KR]
Conservation:-0.842-0.652-0.968-0.6600.3420.749-0.065-0.065-0.0652.7820.749-0.7420.7491.969-0.065-1.420-1.109-0.633-0.633-1.1490.749-0.2631.1550.342-0.253
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1fjs_A_2061fjs   A206230TYFVTGIVSWGEGCARKGKYGIYTKEEEEEEEEEE-SSSS-TT--EEEEEbbbxabbpabexebvxxvbbxbbxx
1gj7_B_2061gj7   B206230RMTLTGIVSWGRGCALKDKPGVYTREEEEEEEEEE-SSSSBTTB-EEEEEbxbxabbpabexeblbplbxxbbxx
1kli_H_2061kli   H206230TWYLTGIVSWGQGCATVGHFGVYTREEEEEEEEEE-STTT-TT--EEEEEbbbxabbpabexeblxpvbbxbbxx
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1fjs_A_2061fjs   A     Z34N-[2-[5-[AMINO(IMINO)METHYL]-2-HYDROXYPHENOXY]-3,5-DIFLUORO-6-[3-(4,5-DIHYDRO-1-METHYL-1H-IMIDAZOL-2-YL) PHENOXY]PYRIDIN-4-YL]-N-METHYLGLYCINE V - 213
1fjs_A_2061fjs   A     Z34N-[2-[5-[AMINO(IMINO)METHYL]-2-HYDROXYPHENOXY]-3,5-DIFLUORO-6-[3-(4,5-DIHYDRO-1-METHYL-1H-IMIDAZOL-2-YL) PHENOXY]PYRIDIN-4-YL]-N-METHYLGLYCINE S - 214
1fjs_A_2061fjs   A     Z34N-[2-[5-[AMINO(IMINO)METHYL]-2-HYDROXYPHENOXY]-3,5-DIFLUORO-6-[3-(4,5-DIHYDRO-1-METHYL-1H-IMIDAZOL-2-YL) PHENOXY]PYRIDIN-4-YL]-N-METHYLGLYCINE W - 215
1fjs_A_2061fjs   A     Z34N-[2-[5-[AMINO(IMINO)METHYL]-2-HYDROXYPHENOXY]-3,5-DIFLUORO-6-[3-(4,5-DIHYDRO-1-METHYL-1H-IMIDAZOL-2-YL) PHENOXY]PYRIDIN-4-YL]-N-METHYLGLYCINE G - 216
1fjs_A_2061fjs   A     Z34N-[2-[5-[AMINO(IMINO)METHYL]-2-HYDROXYPHENOXY]-3,5-DIFLUORO-6-[3-(4,5-DIHYDRO-1-METHYL-1H-IMIDAZOL-2-YL) PHENOXY]PYRIDIN-4-YL]-N-METHYLGLYCINE E - 217
1fjs_A_2061fjs   A     Z34N-[2-[5-[AMINO(IMINO)METHYL]-2-HYDROXYPHENOXY]-3,5-DIFLUORO-6-[3-(4,5-DIHYDRO-1-METHYL-1H-IMIDAZOL-2-YL) PHENOXY]PYRIDIN-4-YL]-N-METHYLGLYCINE G - 218
1fjs_A_2061fjs   A     Z34N-[2-[5-[AMINO(IMINO)METHYL]-2-HYDROXYPHENOXY]-3,5-DIFLUORO-6-[3-(4,5-DIHYDRO-1-METHYL-1H-IMIDAZOL-2-YL) PHENOXY]PYRIDIN-4-YL]-N-METHYLGLYCINE Y - 225
1fjs_A_2061fjs   A     Z34N-[2-[5-[AMINO(IMINO)METHYL]-2-HYDROXYPHENOXY]-3,5-DIFLUORO-6-[3-(4,5-DIHYDRO-1-METHYL-1H-IMIDAZOL-2-YL) PHENOXY]PYRIDIN-4-YL]-N-METHYLGLYCINE G - 226
1fjs_A_2061fjs   A     Z34N-[2-[5-[AMINO(IMINO)METHYL]-2-HYDROXYPHENOXY]-3,5-DIFLUORO-6-[3-(4,5-DIHYDRO-1-METHYL-1H-IMIDAZOL-2-YL) PHENOXY]PYRIDIN-4-YL]-N-METHYLGLYCINE I - 227
1fjs_A_2061fjs   A     Z34N-[2-[5-[AMINO(IMINO)METHYL]-2-HYDROXYPHENOXY]-3,5-DIFLUORO-6-[3-(4,5-DIHYDRO-1-METHYL-1H-IMIDAZOL-2-YL) PHENOXY]PYRIDIN-4-YL]-N-METHYLGLYCINE Y - 228
1fjs_A_2061fjs   A     GOLGLYCEROL K - 230
1gj7_B_2061gj7   B     1326-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE V - 213
1gj7_B_2061gj7   B     1326-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE S - 214
1gj7_B_2061gj7   B     1326-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE W - 215
1gj7_B_2061gj7   B     1326-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE G - 216
1gj7_B_2061gj7   B     1326-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE R - 217
1gj7_B_2061gj7   B     1326-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE K - 224
1gj7_B_2061gj7   B     1326-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE P - 225
1gj7_B_2061gj7   B     1326-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE G - 226
1gj7_B_2061gj7   B     1326-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE V - 227
1gj7_B_2061gj7   B     1326-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE Y - 228
1kli_H_2061kli   H     BENBENZAMIDINE V - 213
1kli_H_2061kli   H     BENBENZAMIDINE S - 214
1kli_H_2061kli   H     BENBENZAMIDINE W - 215
1kli_H_2061kli   H     BENBENZAMIDINE G - 216
1kli_H_2061kli   H     BENBENZAMIDINE Q - 217
1kli_H_2061kli   H     BENBENZAMIDINE F - 225
1kli_H_2061kli   H     BENBENZAMIDINE G - 226
1kli_H_2061kli   H     BENBENZAMIDINE V - 227
1kli_H_2061kli   H     BENBENZAMIDINE Y - 228

Clusters included in this Subclass
CLUSTER: HA.11.1