ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 22.1.2

Subclass Accession number: 858
Subclass: 22.1.2

Type: HA beta-beta hairpin
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 4.2 (>50 %)  4.2.2 (>50 %)
GO : GO:0016829 (>75 %)  GO:0016835 (>50 %)  GO:0016837 (>50 %)
SCOP : 49993 (>75 %)  50006 (>75 %)  74650 (>75 %)

Number of loops: 3

Average sequence ID (%) : 41.9 +/- 12.5
Average RMSD (Å) : 0.467 +/- 0.153

Consensus geometry

d (Å): 5

delta (°): 90-135

theta (°): 135-180

rho (°): 315-360

Consensus Sequence:	XSpRXXppEXhNpENXXGXYXXXGhX
(φψ)-conformation:	bbaabpabbbbllblaaaaaaaalpb

Pattern:	[AGS]	[FL]	[AGN]	[LV]	[ARS]	[LM]	[HVY]	[S]	[KT]	[R]	[IT]	x	[NRS]	[SY]	[E]	[GS]	[GIM]	[N]	[DKS]	[E]	[N]	[GLT]	x	[G]	[RW]	[Y]	[LT]	[GS]	[AD]	[G]	[AM]	[FT]	[NY]	[IL]	[QY]
Conservation:	-0.612	-0.002	-0.858	-0.179	-0.920	0.175	-0.674	0.618	-0.395	1.171	-0.475	-1.412	-0.674	-0.376	1.171	-0.264	-1.412	1.724	-0.797	1.171	1.724	-1.535	-0.776	1.724	0.246	2.278	-0.510	-0.045	-0.524	1.724	-0.599	-0.563	-0.200	0.096	-0.022

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1cb8_A_356	1cb8	A	357	391	SFNVRMVSKRTRRSESGNKENLLGRYLSDGATNIQ	EEEEE---TTSB----BTTBSTT-TTTTSSEEEEE	bbbbbbbbaabbxpxbblvblaaaaaaaavxbxbb
1f1s_A_642	1f1s	A	643	677	GFALSLHSKRTLNYEGMNDENTRGWYTGDGMFYIY	EEEEE---TTSBS---BTTB-TT-TTTTSSEEEEE	bbbbbbbbaabxabbbblvbvaaaaaaaavxbbbb
1j0m_A_407	1j0m	A	407	441	ALGLALYSTRISSYESINSENGRGWYTGAGATYLY	EEEEE---SSSBS----TTB-TT-TTTTSSEEEEE	bbbbbbbbaabxabbbbllblaaaaaaaavxbbbb

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1cb8_A_356	1cb8	A	GOLGLYCEROL	E - 371
1cb8_A_356	1cb8	A	GOLGLYCEROL	E - 376
1cb8_A_356	1cb8	A	GCUD-GLUCURONIC ACID	R - 381

Clusters included in this Subclass

CLUSTER: HA.24.0