PDB: 1axi Compound: growth hormone Classification: COMPLEX (HORMONE/RECEPTOR) Entry date in PDB: 1998-01-28 Resolution [Å]: 2.10 R-Factor: 0.190

CHAIN: A SWISS-PROT/TREMBL: P01241    KEYWORD: 3D-structure    Alternative splicing    Disease mutation    Dwarfism    Hormone    Pharmaceutical    Phosphorylation    Pituitary    Polymorphism    Signal    SCOP: a.26.1.1 All alpha proteins    4-helical cytokines    4-helical cytokines    Long-chain cytokines    Growth hormone, somatotropin    Human (Homo sapiens) GO:  extracellular region    hormone activity    CHAIN: B SWISS-PROT/TREMBL: P10912    KEYWORD: 3D-structure    Alternative splicing    Disease mutation    Dwarfism    Endocytosis    Glycoprotein    Phosphorylation    Polymorphism    Receptor    Signal    Transmembrane    Ubl conjugation    SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Growth hormone receptor    Human (Homo sapiens) SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Growth hormone receptor    Human (Homo sapiens) GO:  membrane    hematopoietin/interferon-class (D200-domain) cytokine receptor activity

Image Source: PDB

Loops in ArchDB40 clusters

1axi_B_106 - HA => SUBCLASS : 2.2.18
1axi_B_35 - HA => SUBCLASS : 5.2.4
1axi_B_172 - HA => SUBCLASS : 6.8.1
1axi_B_196 - AR => SUBCLASS : 3.7.2
1axi_B_93 - AR => SUBCLASS : 8.7.1
1axi_B_116 - AR => SUBCLASS : 10.5.1

Loops in ArchDB95 clusters

1axi_B_93 - AR => SUBCLASS : 8.11.1
1axi_B_93 - AR => SUBCLASS : 9.19.1
1axi_B_116 - AR => SUBCLASS : 10.10.1
1axi_B_106 - HA => SUBCLASS : 2.2.2
1axi_B_35 - HA => SUBCLASS : 5.2.5
1axi_B_172 - HA => SUBCLASS : 6.9.1

Loops not clustered in ArchDB

1axi_B_46 - AR
1axi_B_187 - AR
1axi_B_150 - AR
1axi_B_81 - AR
1axi_B_135 - HA
1axi_B_65 - HA
1axi_B_208 - HA
1axi_A_107 - HH
1axi_A_94 - HH
1axi_A_72 - HH
1axi_A_64 - HH
1axi_A_38 - HH
1axi_A_7 - HH
1axi_A_137 - HH

1a22 B - percentage of sequence identity: 98
1huw - - percentage of sequence identity: 90
1hwg B - percentage of sequence identity: 98
1hwg C - percentage of sequence identity: 98
1hwh B - percentage of sequence identity: 98
1kf9 B - percentage of sequence identity: 98
1kf9 C - percentage of sequence identity: 98
1kf9 E - percentage of sequence identity: 98
1kf9 F - percentage of sequence identity: 98
2aew A - percentage of sequence identity: 98
2aew B - percentage of sequence identity: 98
3hhr B - percentage of sequence identity: 99
3hhr C - percentage of sequence identity: 99