PDB: 1bif Compound: 6-phosphofructo-2-kinase fructose-2,6-bisphosphata Classification: BIFUNCTIONAL ENZYME Entry date in PDB: 1997-11-12 Resolution [Å]: 2.00 R-Factor: 0.183

CHAIN: - SWISS-PROT/TREMBL: P25114    KEYWORD: 3D-structure    ATP-binding    Hydrolase    Kinase    Multifunctional enzyme    Multigene family    Phosphorylation    Testis    Transferase    EC: 2.7.1.105 SCOP: c.37.1.7 Alpha and beta proteins (a/b)    P-loop containing nucleoside triphosphate hydrolases    P-loop containing nucleoside triphosphate hydrolases    6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain    6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain    Rat (Rattus norvegicus) SCOP: c.60.1.4 Alpha and beta proteins (a/b)    Phosphoglycerate mutase-like    Phosphoglycerate mutase-like    6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain    6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain    Rat (Rattus norvegicus) GO:  ATP binding    catalytic activity    fructose 2,6-bisphosphate metabolism    metabolism

Image Source: PDB

Loops in ArchDB40 clusters

1bif_*_418 - HA => SUBCLASS : 2.6.1
1bif_*_418 - HA => SUBCLASS : 3.7.1
1bif_*_214 - HA => SUBCLASS : 4.6.1
1bif_*_297 - EH => SUBCLASS : 2.1.3
1bif_*_297 - EH => SUBCLASS : 2.1.15
1bif_*_124 - EH => SUBCLASS : 4.43.1
1bif_*_39 - EH => SUBCLASS : 6.1.1

Loops in ArchDB95 clusters

1bif_*_297 - EH => SUBCLASS : 3.3.1
1bif_*_124 - EH => SUBCLASS : 4.56.1
1bif_*_223 - EH => SUBCLASS : 4.72.1
1bif_*_39 - EH => SUBCLASS : 6.1.1
1bif_*_260 - HH => SUBCLASS : 10.21.1
1bif_*_134 - HE => SUBCLASS : 1.1.1
1bif_*_51 - HE => SUBCLASS : 2.1.1
1bif_*_96 - HE => SUBCLASS : 3.1.1
1bif_*_304 - HE => SUBCLASS : 4.34.2
1bif_*_275 - HE => SUBCLASS : 5.59.1
1bif_*_391 - HE => SUBCLASS : 15.3.1
1bif_*_418 - HA => SUBCLASS : 2.4.1
1bif_*_214 - HA => SUBCLASS : 4.6.1

Loops in ArchDB-EC clusters

1bif_*_275 - HE => SUBCLASS : 5.40.1

Loops not clustered in ArchDB

1bif_*_69 - EH
1bif_*_150 - EH
1bif_*_251 - EH
1bif_*_318 - EH
1bif_*_385 - EH
1bif_*_429 - EH
1bif_*_214 - HA
1bif_*_418 - HA
1bif_*_365 - HE
1bif_*_183 - HE
1bif_*_232 - HE
1bif_*_74 - HH
1bif_*_161 - HH
1bif_*_336 - HH
1bif_*_344 - HH

1c7z A - percentage of sequence identity: 85
1c7z B - percentage of sequence identity: 85
1c80 A - percentage of sequence identity: 85
1c80 B - percentage of sequence identity: 85
1c81 A - percentage of sequence identity: 85
1fbt B - percentage of sequence identity: 85
1k6m B - percentage of sequence identity: 78
1tip A - percentage of sequence identity: 85
1tip B - percentage of sequence identity: 85
2axn A - percentage of sequence identity: 70
2bif A - percentage of sequence identity: 99
2bif B - percentage of sequence identity: 99
3bif A - percentage of sequence identity: 100