PDB: 1exq Compound: pol polyprotein Classification: VIRUS/VIRAL PROTEIN Entry date in PDB: 2000-11-03 Resolution [Å]: 1.60 R-Factor: 0.253

CHAIN: A SWISS-PROT/TREMBL: P04585    KEYWORD: 3D-structure    AIDS    Aspartyl protease    Endonuclease    Hydrolase    Metal-binding    Nuclease    Polyprotein    RNA-directed DNA polymerase    Transferase    Zinc    Zinc-finger    EC: 2.7.7.49 SCOP: c.55.3.2 Alpha and beta proteins (a/b)    Ribonuclease H-like motif    Ribonuclease H-like    Retroviral integrase, catalytic domain    Retroviral integrase, catalytic domain    Human immunodeficiency virus type 1 GO:  aspartic-type endopeptidase activity    DNA binding    integrase activity    nucleic acid binding    ribonuclease H activity    RNA binding    RNA-directed DNA polymerase activity    zinc ion binding    DNA integration    DNA recombination    proteolysis and peptidolysis    RNA-dependent DNA replication    CHAIN: B SWISS-PROT/TREMBL: P04585    KEYWORD: 3D-structure    AIDS    Aspartyl protease    Endonuclease    Hydrolase    Metal-binding    Nuclease    Polyprotein    RNA-directed DNA polymerase    Transferase    Zinc    Zinc-finger    EC: 2.7.7.49 SCOP: c.55.3.2 Alpha and beta proteins (a/b)    Ribonuclease H-like motif    Ribonuclease H-like    Retroviral integrase, catalytic domain    Retroviral integrase, catalytic domain    Human immunodeficiency virus type 1 GO:  aspartic-type endopeptidase activity    DNA binding    integrase activity    nucleic acid binding    ribonuclease H activity    RNA binding    RNA-directed DNA polymerase activity    zinc ion binding    DNA integration    DNA recombination    proteolysis and peptidolysis    RNA-dependent DNA replication

Image Source: PDB

Loops in ArchDB40 clusters

1exq_A_124 - HE => SUBCLASS : 1.1.1
1exq_A_94 - HE => SUBCLASS : 4.22.1
1exq_A_60 - HA => SUBCLASS : 2.1.1
1exq_A_71 - HA => SUBCLASS : 4.1.1
1exq_A_71 - HA => SUBCLASS : 4.1.2
1exq_A_83 - EH => SUBCLASS : 4.11.9
1exq_A_155 - HH => SUBCLASS : 3.6.7

Loops in ArchDB95 clusters

1exq_A_155 - HH => SUBCLASS : 3.6.4
1exq_A_124 - HE => SUBCLASS : 1.1.1
1exq_A_94 - HE => SUBCLASS : 4.8.1
1exq_A_60 - HA => SUBCLASS : 2.1.1
1exq_A_71 - HA => SUBCLASS : 4.1.1

Loops in ArchDB-EC clusters

1exq_A_94 - HE => SUBCLASS : 4.20.1

Loops not clustered in ArchDB

1exq_A_112 - EH
1exq_A_136 - EH
1exq_A_60 - HA
1exq_A_71 - HA
1exq_A_172 - HH

1b92 A - percentage of sequence identity: 94
1b9d A - percentage of sequence identity: 95
1b9f A - percentage of sequence identity: 94
1bhl - - percentage of sequence identity: 93
1bi4 A - percentage of sequence identity: 94
1bi4 B - percentage of sequence identity: 94
1bi4 C - percentage of sequence identity: 94
1bis A - percentage of sequence identity: 95
1bis B - percentage of sequence identity: 95
1biu A - percentage of sequence identity: 94
1biu B - percentage of sequence identity: 94
1biu C - percentage of sequence identity: 94
1biz A - percentage of sequence identity: 95
1biz B - percentage of sequence identity: 95
1bl3 A - percentage of sequence identity: 94
1bl3 B - percentage of sequence identity: 94
1bl3 C - percentage of sequence identity: 94
1ex4 A - percentage of sequence identity: 100
1ex4 B - percentage of sequence identity: 100
1exq A - percentage of sequence identity: 100
1exq B - percentage of sequence identity: 100
1hyv A - percentage of sequence identity: 95
1hyz A - percentage of sequence identity: 95
1itg - - percentage of sequence identity: 95
1k6y A - percentage of sequence identity: 96
1k6y B - percentage of sequence identity: 96
1k6y C - percentage of sequence identity: 96
1k6y D - percentage of sequence identity: 96
1qs4 A - percentage of sequence identity: 94
1qs4 B - percentage of sequence identity: 94
1qs4 C - percentage of sequence identity: 94
2b4j A - percentage of sequence identity: 95
2b4j B - percentage of sequence identity: 95
2itg - - percentage of sequence identity: 94