PDB: 1kfu Compound: m-calpain large subunit Classification: HYDROLASE Entry date in PDB: 2001-12-07 Resolution [Å]: 2.50 R-Factor: 0.221

CHAIN: L SWISS-PROT/TREMBL: P17655    KEYWORD: 3D-structure    Calcium-binding    Hydrolase    Multigene family    Polymorphism    Repeat    Thiol protease    EC: 3.4.22.53 SCOP: a.39.1.8 All alpha proteins    EF Hand-like    EF-hand    Penta-EF-hand proteins    Calpain large subunit, C-terminal domain (domain IV)    Human (Homo sapiens), M-type SCOP: b.14.1.1 All beta proteins    Calpain large subunit, middle domain (domain III)    Calpain large subunit, middle domain (domain III)    Calpain large subunit, middle domain (domain III)    Calpain large subunit, middle domain (domain III)    Human (Homo sapiens), M-type SCOP: d.3.1.3 Alpha and beta proteins (a+b)    Cysteine proteinases    Cysteine proteinases    Calpain large subunit, catalytic domain (domain II)    Calpain large subunit, catalytic domain (domain II)    Human (Homo sapiens), M-type GO:  intracellular    calcium ion binding    calpain activity    cysteine-type endopeptidase activity    proteolysis and peptidolysis    CHAIN: S SWISS-PROT/TREMBL: P04632    KEYWORD: 3D-structure    Calcium-binding    Repeat    SCOP: a.39.1.8 All alpha proteins    EF Hand-like    EF-hand    Penta-EF-hand proteins    Calpain small (regulatory) subunit (domain VI)    Human (Homo sapiens) GO:  calcium ion binding

Image Source: PDB

Loops in ArchDB95 clusters

1kfu_L_591 - EH => SUBCLASS : 0.1.11
1kfu_L_656 - EH => SUBCLASS : 1.1.4
1kfu_L_591 - EH => SUBCLASS : 1.1.43
1kfu_L_622 - EH => SUBCLASS : 1.2.2
1kfu_L_211 - EH => SUBCLASS : 5.6.1
1kfu_L_211 - EH => SUBCLASS : 5.6.3
1kfu_L_97 - EH => SUBCLASS : 6.13.1
1kfu_L_149 - AR => SUBCLASS : 2.4.2
1kfu_L_164 - AR => SUBCLASS : 3.1.17
1kfu_L_495 - AR => SUBCLASS : 3.1.18
1kfu_L_105 - HH => SUBCLASS : 1.2.42
1kfu_S_894 - HH => SUBCLASS : 5.1.1
1kfu_S_926 - HH => SUBCLASS : 8.10.1
1kfu_S_841 - HH => SUBCLASS : 9.2.2
1kfu_S_862 - HH => SUBCLASS : 9.2.2
1kfu_S_841 - HH => SUBCLASS : 9.2.3
1kfu_L_224 - HE => SUBCLASS : 1.1.1
1kfu_L_200 - HE => SUBCLASS : 2.1.15
1kfu_L_640 - HE => SUBCLASS : 5.29.2
1kfu_L_574 - HE => SUBCLASS : 6.3.1
1kfu_L_138 - HA => SUBCLASS : 2.1.1

Loops not clustered in ArchDB

1kfu_L_470 - AR
1kfu_L_474 - AR
1kfu_L_406 - AR
1kfu_L_388 - AR
1kfu_L_363 - AR
1kfu_L_336 - AR
1kfu_L_481 - AR
1kfu_L_169 - EH
1kfu_L_73 - EH
1kfu_L_279 - EH
1kfu_L_25 - EH
1kfu_L_548 - EH
1kfu_L_509 - EH
1kfu_L_429 - EH
1kfu_L_158 - HA
1kfu_L_264 - HA
1kfu_L_237 - HA
1kfu_L_595 - HE
1kfu_L_533 - HE
1kfu_L_450 - HE
1kfu_L_310 - HE
1kfu_L_118 - HE
1kfu_L_78 - HE
1kfu_L_32 - HE
1kfu_L_4 - HE
1kfu_L_627 - HH
1kfu_L_550 - HH
1kfu_L_177 - HH
1kfu_S_907 - HH
1kfu_S_817 - HH
1kfu_S_796 - HH
1kfu_L_659 - HH

1alv A - percentage of sequence identity: 97
1df0 A - percentage of sequence identity: 93
1dvi A - percentage of sequence identity: 91
1kfx L - percentage of sequence identity: 100
1kxr B - percentage of sequence identity: 70
1mdw B - percentage of sequence identity: 93
1np8 A - percentage of sequence identity: 91
1tl9 A - percentage of sequence identity: 70
1tlo A - percentage of sequence identity: 70
1u5i A - percentage of sequence identity: 93
1zcm A - percentage of sequence identity: 71
2ary A - percentage of sequence identity: 71
2ary B - percentage of sequence identity: 71