PDB: 1m6i Compound: programmed cell death protein 8 Classification: OXIDOREDUCTASE Entry date in PDB: 2002-08-28 Resolution [Å]: 1.80 R-Factor: 0.225

CHAIN: A SWISS-PROT/TREMBL: O95831    KEYWORD: 3D-structure    Alternative splicing    Apoptosis    FAD    Flavoprotein    Mitochondrion    Nuclear protein    Oxidoreductase    Transit peptide    EC: 1.-.-.- SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Apoptosis-inducing factor (AIF)    Human (Homo sapiens) SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Apoptosis-inducing factor (AIF)    Human (Homo sapiens) SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Apoptosis-inducing factor (AIF)    Human (Homo sapiens) SCOP: d.87.1.1 Alpha and beta proteins (a+b)    CO dehydrogenase flavoprotein C-domain-like    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    Apoptosis-inducing factor (AIF)    Human (Homo sapiens) GO:  disulfide oxidoreductase activity    oxidoreductase activity    electron transport

Image Source: PDB

Loops in ArchDB40 clusters

1m6i_A_369 - HA => SUBCLASS : 2.1.1
1m6i_A_428 - HA => SUBCLASS : 2.2.1
1m6i_A_562 - HA => SUBCLASS : 2.3.7
1m6i_A_192 - HA => SUBCLASS : 3.1.1
1m6i_A_440 - HA => SUBCLASS : 3.2.1
1m6i_A_481 - HA => SUBCLASS : 3.4.2
1m6i_A_233 - HA => SUBCLASS : 4.1.1
1m6i_A_242 - HA => SUBCLASS : 4.2.3
1m6i_A_448 - EH => SUBCLASS : 2.3.8
1m6i_A_131 - EH => SUBCLASS : 3.2.1
1m6i_A_262 - EH => SUBCLASS : 3.5.1
1m6i_A_329 - EH => SUBCLASS : 11.2.1
1m6i_A_388 - AR => SUBCLASS : 1.1.4
1m6i_A_224 - AR => SUBCLASS : 1.2.3
1m6i_A_362 - AR => SUBCLASS : 1.2.3
1m6i_A_393 - AR => SUBCLASS : 3.12.1
1m6i_A_433 - AR => SUBCLASS : 3.19.1

Loops in ArchDB95 clusters

1m6i_A_448 - EH => SUBCLASS : 2.4.8
1m6i_A_448 - EH => SUBCLASS : 2.4.12
1m6i_A_131 - EH => SUBCLASS : 3.5.1
1m6i_A_262 - EH => SUBCLASS : 3.7.1
1m6i_A_329 - EH => SUBCLASS : 11.6.1
1m6i_A_388 - AR => SUBCLASS : 1.2.2
1m6i_A_362 - AR => SUBCLASS : 2.6.1
1m6i_A_224 - AR => SUBCLASS : 2.6.1
1m6i_A_433 - AR => SUBCLASS : 3.19.1
1m6i_A_421 - AR => SUBCLASS : 4.13.3
1m6i_A_275 - HE => SUBCLASS : 0.1.13
1m6i_A_346 - HE => SUBCLASS : 1.1.1
1m6i_A_346 - HE => SUBCLASS : 1.2.1
1m6i_A_187 - HE => SUBCLASS : 1.2.5
1m6i_A_310 - HE => SUBCLASS : 2.1.1
1m6i_A_310 - HE => SUBCLASS : 2.1.5
1m6i_A_287 - HE => SUBCLASS : 2.2.1
1m6i_A_141 - HE => SUBCLASS : 4.1.1
1m6i_A_369 - HA => SUBCLASS : 2.1.1
1m6i_A_428 - HA => SUBCLASS : 2.2.1
1m6i_A_562 - HA => SUBCLASS : 2.3.7
1m6i_A_192 - HA => SUBCLASS : 3.1.1
1m6i_A_440 - HA => SUBCLASS : 3.3.1
1m6i_A_481 - HA => SUBCLASS : 3.5.1
1m6i_A_233 - HA => SUBCLASS : 4.1.1
1m6i_A_242 - HA => SUBCLASS : 4.3.3

Loops in ArchDB-EC clusters

1m6i_A_517 - HH => SUBCLASS : 4.4.1

Loops not clustered in ArchDB

1m6i_A_224 - AR
1m6i_A_250 - AR
1m6i_A_200 - AR
1m6i_A_200 - AR
1m6i_A_250 - AR
1m6i_A_362 - AR
1m6i_A_388 - AR
1m6i_A_393 - AR
1m6i_A_421 - AR
1m6i_A_433 - AR
1m6i_A_491 - AR
1m6i_A_491 - AR
1m6i_A_158 - EH
1m6i_A_281 - EH
1m6i_A_302 - EH
1m6i_A_400 - EH
1m6i_A_504 - EH
1m6i_A_572 - EH
1m6i_A_378 - HA
1m6i_A_481 - HA
1m6i_A_440 - HA
1m6i_A_428 - HA
1m6i_A_378 - HA
1m6i_A_369 - HA
1m6i_A_242 - HA
1m6i_A_233 - HA
1m6i_A_192 - HA
1m6i_A_562 - HA
1m6i_A_407 - HE
1m6i_A_455 - HE
1m6i_A_529 - HE
1m6i_A_268 - HH

1gv4 B - percentage of sequence identity: 95