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Information on 1uea
PDB: 1uea
Compound: matrix metalloproteinase-3
Classification: COMPLEX (METALLOPROTEASE/INHIBITOR)
Entry date in PDB: 1998-10-14
Resolution [Å]: 2.80
R-Factor: 0.197


CHAIN: A
SWISS-PROT/TREMBL: P08254
   KEYWORD: 3D-structure    Calcium-binding    Collagen degradation    Extracellular matrix    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Polymorphism    Signal    Zinc    Zymogen   
EC: 3.4.24.17
SCOP: d.92.1.11 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Matrix metalloproteases, catalytic domain    Stromelysin-1 (MMP-3)    Human (Homo sapiens), fibroblast
GO:  extracellular matrix (sensu Metazoa)    metalloendopeptidase activity    metallopeptidase activity    zinc ion binding    proteolysis and peptidolysis   


CHAIN: B
SWISS-PROT/TREMBL: P01033
   KEYWORD: 3D-structure    Erythrocyte maturation    Glycoprotein    Metalloprotease inhibitor    Signal   
SCOP: b.40.3.1 All beta proteins    OB-fold    TIMP-like    Tissue inhibitor of metalloproteinases, TIMP    TIMP-1    Human (Homo sapiens)
GO:  extracellular matrix (sensu Metazoa)    metalloendopeptidase inhibitor activity   


CHAIN: C
SWISS-PROT/TREMBL: P08254
   KEYWORD: 3D-structure    Calcium-binding    Collagen degradation    Extracellular matrix    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Polymorphism    Signal    Zinc    Zymogen   
EC: 3.4.24.17
SCOP: d.92.1.11 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Matrix metalloproteases, catalytic domain    Stromelysin-1 (MMP-3)    Human (Homo sapiens), fibroblast
GO:  extracellular matrix (sensu Metazoa)    metalloendopeptidase activity    metallopeptidase activity    zinc ion binding    proteolysis and peptidolysis   


CHAIN: D
SWISS-PROT/TREMBL: P01033
   KEYWORD: 3D-structure    Erythrocyte maturation    Glycoprotein    Metalloprotease inhibitor    Signal   
SCOP: b.40.3.1 All beta proteins    OB-fold    TIMP-like    Tissue inhibitor of metalloproteinases, TIMP    TIMP-1    Human (Homo sapiens)
GO:  extracellular matrix (sensu Metazoa)    metalloendopeptidase inhibitor activity   
1uea Image
Image Source: PDB
Homologous structures to 1uea classified in ArchDB

1cgl A - percentage of sequence identity: 60
1cxv A - percentage of sequence identity: 60
1hfc - - percentage of sequence identity: 61
1hy7 A - percentage of sequence identity: 100
1q3a A - percentage of sequence identity: 84
1slm - - percentage of sequence identity: 100
830c A - percentage of sequence identity: 62