ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 7.40.1

Subclass Accession number: 3460
Subclass: 7.40.1

Type: EH beta-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 3.2 (>50 %)  3.2.1 (>50 %)  3.2.1.52
GO : GO:0004553 (>50 %)  GO:0015929 (>50 %)  GO:0016798 (>50 %)
SCOP : 51445 (>75 %)  51550 (>75 %)

Number of loops: 3

Average sequence ID (%) : 37.2 +/- 14.8
Average RMSD (Å) : 0.467 +/- 0.153

Consensus geometry

d (Å): 13

delta (°): 45-90

theta (°): 135-180

rho (°): 0-45

Consensus Sequence:	hDXXRphXXXc
(φψ)-conformation:	bbaaabpbpaa

Pattern:	[HWY]	[R]	[GS]	[AI]	[FLM]	[IL]	[D]	[TV]	[AS]	[R]	[HN]	[FY]	[FHL]	x	[KV]	[DK]	x	[IV]	[KL]	[KR]	[LTY]	[IL]	[D]	[AQR]	[MV]	[A]
Conservation:	0.256	1.296	-0.020	-0.796	-0.507	0.081	1.920	-0.417	-0.198	1.296	0.970	1.126	-1.131	-1.269	-0.984	-0.240	-1.616	0.377	-1.000	0.410	-1.269	0.085	1.920	-0.992	0.032	0.672

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1jak_A_153	1jak	A	153	178	WRSAMLDVSRHFFGVDEVKRYIDRVA	EEEEEEE-SSS---HHHHHHHHHHHH	bbbbbbxaaabxbxaaaaaaaaaaaa
1now_A_202	1now	A	202	227	HRGILIDTSRHYLPVKIILKTLDAMA	EEEEEEESSSS---HHHHHHHHHHHH	bbbbxbbaaabxbwaaaaaaaaaaaa
1qba_*_340	1qba	-	340	365	YRGIFLDVARNFHKKDAVLRLLDQMA	EEEEEEE-SSS---HHHHHHHHHHHH	bbbbbbxaaabxbxaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1jak_A_153	1jak	A	IFG(2R,3R,4S,5R)-2-ACETAMIDO-3,4-DIHYDROXY-5-HYDROXYMETHYL-PIPERIDINIUM	D - 159
1jak_A_153	1jak	A	IFG(2R,3R,4S,5R)-2-ACETAMIDO-3,4-DIHYDROXY-5-HYDROXYMETHYL-PIPERIDINIUM	R - 162
1now_A_202	1now	A	IFG(2R,3R,4S,5R)-2-ACETAMIDO-3,4-DIHYDROXY-5-HYDROXYMETHYL-PIPERIDINIUM	D - 208
1now_A_202	1now	A	IFG(2R,3R,4S,5R)-2-ACETAMIDO-3,4-DIHYDROXY-5-HYDROXYMETHYL-PIPERIDINIUM	R - 211

Clusters included in this Subclass