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Information on SUBCLASS 5.1.1
Subclass Accession number: 132
Subclass: 5.1.1
Type: HE alpha-beta
DB: ArchDB-KI
 Number of loops: 11

Average sequence ID (%) : 26.1 +/- 6.4
Average RMSD (Å) : 1.03 +/- 0.41

Consensus geometry
d (Å): 15 delta (°): 90-135 theta (°): 135-180 rho (°): 0-45
Consensus Sequence: pXhXphpXh
(φψ)-conformation: aagbppabb
Pattern: xxxxx{AELM}[FLM][AEK][DEKRT]xxx{EKNQR}{LPV}[DEKT]x[AFILV][IL]x[FILV][DKS]
Conservation:-0.684-0.7470.478-0.123-0.760-0.5131.1661.1270.129-1.285-1.287-1.3950.106-0.7030.891-0.7330.3002.031-0.5430.8191.724
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1ak2_*_1061ak2   -110130EMLDDLMEKRKEKLDSVIEFSHHHHHHHHHHT----EEEEEEaaaaaaaaaavbbxabbxbxx
1ake_A_901ake   A90110IPQADAMKEAGINVDYVLEFDHHHHHHHHHTT---SEEEEEEaaaaaaaaaavbxbabbbbbx
1aky_*_951aky   -99119EKLDQMLKEQGTPLEKAIELKHHHHHHHHHHT----EEEEEEaaaaaaaaaavb-xabbxxxx
1ank_A_901ank   A90110IPQADAMKEAGINVDYVLEFDHHHHHHTTTTT---SEEEEEEaaaaaaaaaNvxxbabbxxxx
1dvr_A_951dvr   A99119EKLDQMLKEQGTPLEKAIELKHHHHHHHHHHT---SEEEEEEaaaaaaaaaagbxpabbbbxb
1uky_*_1091uky   -109129MDQAISFERDIVESKFILFFDHHHHHHHHHHT---SEEEEEEaaaaaaaaaaabxxabbxbxx
1ukz_*_1091ukz   -109129MDQAISFERDIVESKFILFFDHHHHHHHHHHT---SEEEEEEaaaaaaaaaaabxxabbbbxx
1zak_A_961zak   A96116YSQAMALETLEIRPDTFILLDHHHHHHHHTTT---SEEEEEEaaaaaaaaaavbbxabbxbxx
1zip_*_901zip   -94114EALETMLADIGRKLDYVIHIDHHHHHHHHTTT----EEEEEEaaaaaaaaaavbbxabbxxxx
2eck_A_902eck   A90110IPQADAMKEAGINVDYVLEFDHHHHHHHHHTT---SEEEEEEaaaaaaaaaavxxbabbbxxx
3adk_*_993adk   -99119VKQGEEFERKIGQPTLLLYVDHHHHHHHHHHT---SEEEEEEaaaaaaaaaaabxxabbxbxx
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1ake_A_901ake   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE Q - 92
1aky_*_951aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE Q - 97
1aky_*_951aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE L - 118
1ank_A_901ank   A     AMPADENOSINE MONOPHOSPHATE Q - 92
1dvr_A_951dvr   A     ATFPHOSPHODIFLUOROMETHYLPHOSPHONIC ACID-ADENYLATE ESTER L - 118
1uky_*_1091uky   *     ADPADENOSINE-5'-DIPHOSPHATE Q - 111
1ukz_*_1091ukz   *     AMPADENOSINE MONOPHOSPHATE Q - 111
1zak_A_961zak   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE Q - 98
1zak_A_961zak   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE L - 115
1zip_*_901zip   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE Q - 92
2eck_A_902eck   A     AMPADENOSINE MONOPHOSPHATE Q - 92
Bibliographic annotations
LoopPDBChainAnnotationResidue
1ake_A_901ake   RefC.W.MUELLER,G.E.SCHULZ. STRUCTURE OF THE COMPLEX BETWEEN ADENYLATE KINASE FROM ESCHERICHIA COLI AND THE INHIBITOR AP=5=A REFINED AT 1.9 ANGSTROMS RESOLUTION: A MODEL FOR A CATALYTIC TRANSITION STATE  J.MOL.BIOL. v.224;159,1992AAMP BINDING RESIDUE Q - 92
1ank_A_901ank   RefM.B.BERRY,B.MEADOR,T.BILDERBACK,P.LIANG,M.GLASER,G.N.PHILLIPS JUNIOR. THE CLOSED CONFORMATION OF A HIGHLY FLEXIBLE PROTEIN: THE STRUCTURE OF E. COLI ADENYLATE KINASE WITH BOUND AMP AND AMPPNP  PROTEINS v.19;183,1994AAMP BINDING RESIDUE Q - 92
1ank_A_901ank   RefM.B.BERRY,B.MEADOR,T.BILDERBACK,P.LIANG,M.GLASER,G.N.PHILLIPS JUNIOR. THE CLOSED CONFORMATION OF A HIGHLY FLEXIBLE PROTEIN: THE STRUCTURE OF E. COLI ADENYLATE KINASE WITH BOUND AMP AND AMPPNP  PROTEINS v.19;183,1994ATHERMO-SENSIBLE MUTATION RESIDUEL - 107
2eck_A_902eck   RefM.B.BERRY,T.BILDERBACK,M.GLASER,G.N.PHILLIPS JUNIOR. A CRYSTAL STRUCTURE OF E. COLI ADENYLATE KINASE WITH BOUND AMP AND ADP  PROTEINS v.15;276,1998AAMP BINDING RESIDUE Q - 92
2eck_A_902eck   RefM.B.BERRY,T.BILDERBACK,M.GLASER,G.N.PHILLIPS JUNIOR. A CRYSTAL STRUCTURE OF E. COLI ADENYLATE KINASE WITH BOUND AMP AND ADP  PROTEINS v.15;276,1998ATHERMO-SENSIBLE MUTATION RESIDUEL - 107

Clusters included in this Subclass
CLUSTER: HE.5.22
CLUSTER: HE.6.11
CLUSTER: HE.8.3