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Information on SUBCLASS 6.2.1
Subclass Accession number: 1930
Subclass: 6.2.1 PSSM
Type: AR beta-beta link
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
GO : GO:0003676 (>75 %)  GO:0003677 (>75 %)  GO:0003723 (>75 %)  GO:0003964 (>75 %)  GO:0004175 (>75 %)  GO:0004190 (>75 %)  GO:0004518 (>75 %)  GO:0004519 (>75 %)  GO:0004540 (>75 %)  GO:0008233 (>75 %)  GO:0008270 (>75 %)  GO:0008907 (>75 %)  GO:0016772 (>75 %)  GO:0016779 (>75 %)  GO:0016788 (>75 %)  GO:0030151 (>75 %)  GO:0046914 (>75 %)  
SCOP : 50493 (>75 %)  50494 (>75 %)  50629 (>75 %)  50630 (>75 %)  50631 (>75 %)  50684 (>75 %)  50692 (>75 %)  50696 (>75 %)  
 Number of loops: 5

Average sequence ID (%) : 35.0 +/- 29.4
Average RMSD (Å) : 0.760 +/- 0.586

Consensus geometry
d (Å): 11 delta (°): 90-135 theta (°): 135-180 rho (°): 0-45
Consensus Sequence: XXXhhcXXhh
(φψ)-conformation: bbaababpbb
Pattern: x[lpy][IKL][eknt][AFKV][LV][l][AD][PST][GW][AL][DK]x[st][IV][IL]
Conservation:-1.441-1.123-0.310-1.125-1.0990.919-0.6250.6440.1721.1870.2391.062-1.004-0.2081.5631.150
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1fmb_*_181fmb   -1833TPLNVLLDTGADTSVLEEEEEEE-TT-SS-EEbwbxbxxbaababxbx
1nh0_A_181nh0   A1833QLKEALLDTGADDTVLEEEEEEE-TT-SS-EExxbbbxxbaababxbb
1ve9_A_1961ve9   A200215GQIIKVDAPWLKNFIIEEEEEEE-TT--SEEEbbbbxbbbaaxabxbb
2rsp_A_292rsp   A3045VYITALLDSGADITIIEEEEEEE-TT-SS-EEbbbbbxxbaababxbx
4fiv_*_234fiv   -2338YPIKFLLDTGADITILEEEEEEE-TT-SS-EEbwbxxxxbaababxbb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1fmb_*_181fmb   *     HYB[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYL-VALINYL]-PHENYLALANINOL L - 23
1fmb_*_181fmb   *     HYB[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYL-VALINYL]-PHENYLALANINOL D - 25
1fmb_*_181fmb   *     HYB[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYL-VALINYL]-PHENYLALANINOL T - 26
1fmb_*_181fmb   *     HYB[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYL-VALINYL]-PHENYLALANINOL G - 27
1fmb_*_181fmb   *     HYB[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYL-VALINYL]-PHENYLALANINOL A - 28
1fmb_*_181fmb   *     HYB[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYL-VALINYL]-PHENYLALANINOL D - 29
1fmb_*_181fmb   *     HYB[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYL-VALINYL]-PHENYLALANINOL T - 30
1fmb_*_181fmb   *     HYB[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYL-VALINYL]-PHENYLALANINOL S - 31
1fmb_*_181fmb   *     HYB[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYL-VALINYL]-PHENYLALANINOL V - 32
1nh0_A_181nh0   A     KI23-BENZYLOXYCARBONYLAMINO-2-HYDROXY-4-PHENYL-BUTYRIC ACID L - 23
1nh0_A_181nh0   A     KI23-BENZYLOXYCARBONYLAMINO-2-HYDROXY-4-PHENYL-BUTYRIC ACID D - 25
1nh0_A_181nh0   A     KI23-BENZYLOXYCARBONYLAMINO-2-HYDROXY-4-PHENYL-BUTYRIC ACID G - 27
1nh0_A_181nh0   A     KI23-BENZYLOXYCARBONYLAMINO-2-HYDROXY-4-PHENYL-BUTYRIC ACID A - 28
1nh0_A_181nh0   A     NH2AMINO GROUP D - 29
1nh0_A_181nh0   A     NH2AMINO GROUP D - 30
1ve9_A_1961ve9   A     FADFLAVIN-ADENINE DINUCLEOTIDE G - 198
1ve9_A_1961ve9   A     FADFLAVIN-ADENINE DINUCLEOTIDE R - 199
1ve9_A_1961ve9   A     FADFLAVIN-ADENINE DINUCLEOTIDE G - 200
1ve9_A_1961ve9   A     FADFLAVIN-ADENINE DINUCLEOTIDE Q - 201
1ve9_A_1961ve9   A     FADFLAVIN-ADENINE DINUCLEOTIDE I - 202
1ve9_A_1961ve9   A     BEZBENZOIC ACID I - 202
1ve9_A_1961ve9   A     BEZBENZOIC ACID I - 215
4fiv_*_234fiv   *     1NI4-[2-(2-ACETYLAMINO-3-NAPHTHALEN-1-YL-PROPIONYLAMINO)-3-METHYL-BUTYRYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL) -PROPYL]-AMIDE L - 28
4fiv_*_234fiv   *     1NI4-[2-(2-ACETYLAMINO-3-NAPHTHALEN-1-YL-PROPIONYLAMINO)-3-METHYL-BUTYRYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL) -PROPYL]-AMIDE D - 30
4fiv_*_234fiv   *     1NI4-[2-(2-ACETYLAMINO-3-NAPHTHALEN-1-YL-PROPIONYLAMINO)-3-METHYL-BUTYRYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL) -PROPYL]-AMIDE T - 31
4fiv_*_234fiv   *     1NI4-[2-(2-ACETYLAMINO-3-NAPHTHALEN-1-YL-PROPIONYLAMINO)-3-METHYL-BUTYRYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL) -PROPYL]-AMIDE G - 32
4fiv_*_234fiv   *     1NI4-[2-(2-ACETYLAMINO-3-NAPHTHALEN-1-YL-PROPIONYLAMINO)-3-METHYL-BUTYRYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL) -PROPYL]-AMIDE A - 33
4fiv_*_234fiv   *     1NI4-[2-(2-ACETYLAMINO-3-NAPHTHALEN-1-YL-PROPIONYLAMINO)-3-METHYL-BUTYRYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL) -PROPYL]-AMIDE D - 34
4fiv_*_234fiv   *     1NI4-[2-(2-ACETYLAMINO-3-NAPHTHALEN-1-YL-PROPIONYLAMINO)-3-METHYL-BUTYRYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL) -PROPYL]-AMIDE I - 35
4fiv_*_234fiv   *     1NI4-[2-(2-ACETYLAMINO-3-NAPHTHALEN-1-YL-PROPIONYLAMINO)-3-METHYL-BUTYRYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL) -PROPYL]-AMIDE T - 36
4fiv_*_234fiv   *     1NI4-[2-(2-ACETYLAMINO-3-NAPHTHALEN-1-YL-PROPIONYLAMINO)-3-METHYL-BUTYRYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL) -PROPYL]-AMIDE I - 37

Clusters included in this Subclass
CLUSTER: AR.6.16