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Information on SUBCLASS 2.2.7
Subclass Accession number: 2213
Subclass: 2.2.7 PSSM
Type: HH alpha-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
GO : GO:0016773 (>75 %)  GO:0046914 (>75 %)  
SCOP : 47239 (>50 %)  47240 (>50 %)  47241 (>75 %)  
Number of loops: 12

Average sequence ID (%) : 16.0 +/- 16.1
Average RMSD (Å) : 0.500 +/- 0.160

Consensus geometry
d (Å): 5 delta (°): 90-135 theta (°): 135-180 rho (°): 135-180
Consensus Sequence: pXGchX
(φψ)-conformation: aalpaa
Pattern: [ADEGQRS]x[ailtv]xxxxxxx[ACFILMT][degkqr]x[acsv][adegks][eknq][aenq][EGK][dkny][acfilp][akltv][iklt][afim][degkqr]x[CFLV]xx[agi]xx[adegst]xx[adgkqr][dehks]
Conservation:0.140-0.878-0.192-0.723-0.441-0.530-0.322-1.098-0.452-1.3500.275-0.410-0.4381.4640.2011.3230.4543.7681.325-1.101-0.1040.2380.6360.431-0.1311.699-0.909-0.430-0.404-0.322-1.181-0.186-0.358-0.262-0.7591.027
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1afr_A_1851afr   A197232RATFISHGNTARQAKEHGDIKLAQICGTIAADEKRHHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHaaaaaaaaaaaaaaaaavbaaaaaaaaaaaaaaaaa
1bgf_*_501bgf   -5893QNLLIQLDEQLGRVSKEKNLLLIHNLKRIRKVLQGKHHHHHHHHHHHHHHHHHT-HHHHHHHHHHHHHHHHHaaaaaaaaaaaaaaaaalxaaaaaaaaaaaaaaaaa
1j30_A_81j30   A2156SMANRRYLYFAKRADEEGYPEIAGLLRSIAEGETAHHHHHHHHHHHHHHHHHHT-HHHHHHHHHHHHHHHHHaaaaaaaaaaaaaaaaavbaaaaaaaaaaaaaaaaa
1jig_A_911jig   A103138SALIQELKEGMEVAGEAGDATSADMLLAIHTTLEQHHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHaaaaaaaaaaaaaaaaavbaaaaaaaaaaaaaaaaa
1moj_A_1151moj   A127162GDIIEATREHTELAENLGDHATAHMLREGLIELEDDHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHaaaaaaaaaaaaaaaaavxaaaaaaaaaaaaaaaaa
1nf4_A_881nf4   A100135DATIEAYSQFLKVCKEQGDIVTARLFERIIEEEQAHHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHaaaaaaaaaaaaaaaaalbaaaaaaaaaaaaaaaaa
1nnq_A_61nnq   A2055SMAHMRYLIFAEKAEQEGFPNIAKLFRAIAYAEFVHHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHaaaaaaaaaaaaaaaaavbaaaaaaaaaaaaaaaaa
1o9r_A_1031o9r   A115150GEVANMIRKAIDDSDEAGDPTTADIFTAASRDLDKSHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHaaaaaaaaaaaaaaaaavbaaaaaaaaaaaaaaaaa
1pie_A_2741pie   A283318AVYENNRTKIAQKAFVAGNLTKFGELLNASHASLKDHHHHHHHHHHHHHHHHHT-HHHHHHHHHHHHHHHHHaaaaaaaaaaaaaaaaavxaaaaaaaaaaaaaaaaa
1umn_A_1111umn   A123158RYLAALFQKGFDVSDEEGDSVTNDIFNVAKASIEKHHHHHHHHHHHHHHHHHHT-HHHHHHHHHHHHHHHHHaaaaaaaaaaaaaaaaavxaaaaaaaaaaaaaaaaa
1us7_B_1841us7   B184219EETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFIHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHaaaaaaaaaaaaaaaaavxaaaaaaaaaaaaaaaaa
2e2a_A_32e2a   A1752AGDARSKLLEALKAAENGDFAKADSLVVEAGSCIAEHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHaaaaaaaaaaaaaaaaavxaaaaaaaaaaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1afr_A_1851afr   A     FE2FE (II) ION E - 196
1afr_A_1851afr   A     FE2FE (II) ION T - 199
1afr_A_1851afr   A     FE2FE (II) ION H - 203
1afr_A_1851afr   A     FE2FE (II) ION I - 225
1afr_A_1851afr   A     FE2FE (II) ION D - 228
1afr_A_1851afr   A     FE2FE (II) ION E - 229
1afr_A_1851afr   A     FE2FE (II) ION H - 232
1j30_A_81j30   A     O2OXYGEN MOLECULE G - 19
1j30_A_81j30   A     FEFE (III) ION E - 20
1j30_A_81j30   A     ZNZINC ION E - 20
1j30_A_81j30   A     O2OXYGEN MOLECULE E - 20
1j30_A_81j30   A     FEFE (III) ION A - 23
1j30_A_81j30   A     ZNZINC ION A - 23
1j30_A_81j30   A     O2OXYGEN MOLECULE A - 23
1j30_A_81j30   A     ZNZINC ION Y - 27
1j30_A_81j30   A     O2OXYGEN MOLECULE Y - 27
1j30_A_81j30   A     ZNZINC ION I - 49
1j30_A_81j30   A     FEFE (III) ION G - 52
1j30_A_81j30   A     FEFE (III) ION E - 53
1j30_A_81j30   A     ZNZINC ION E - 53
1j30_A_81j30   A     O2OXYGEN MOLECULE E - 53
1j30_A_81j30   A     FEFE (III) ION H - 56
1j30_A_81j30   A     ZNZINC ION H - 56
1j30_A_81j30   A     O2OXYGEN MOLECULE H - 56
1moj_A_1151moj   A     FEFE (III) ION H - 150
1moj_A_1151moj   A     FEFE (III) ION E - 154
1moj_A_1151moj   A     MGMAGNESIUM ION H - 164
1moj_A_1151moj   A     MGMAGNESIUM ION E - 167
1moj_A_1151moj   A     MGMAGNESIUM ION H - 168
1nf4_A_881nf4   A     FE2FE (II) ION E - 99
1nf4_A_881nf4   A     FE2FE (II) ION T - 102
1nf4_A_881nf4   A     FE2FE (II) ION Y - 106
1nf4_A_881nf4   A     FE2FE (II) ION I - 128
1nf4_A_881nf4   A     FE2FE (II) ION E - 131
1nf4_A_881nf4   A     FE2FE (II) ION E - 132
1nf4_A_881nf4   A     FE2FE (II) ION H - 135
1nf4_A_881nf4   A     FE2FE (II) ION L - 136
1nf4_A_881nf4   A     FE2FE (II) ION Y - 139
1nnq_A_61nnq   A     ZNZINC ION E - 19
1nnq_A_61nnq   A     ZNZINC ION A - 22
1nnq_A_61nnq   A     ZNZINC ION Y - 26
1nnq_A_61nnq   A     ZNZINC ION I - 48
1nnq_A_61nnq   A     ZNZINC ION A - 51
1nnq_A_61nnq   A     ZNZINC ION E - 52
1nnq_A_61nnq   A     ZNZINC ION H - 55
1o9r_A_1031o9r   A     TMNTRIS(HYDROXYMETHYL)AMINOMETHANE D - 138
1o9r_A_1031o9r   A     TMNTRIS(HYDROXYMETHYL)AMINOMETHANE T - 141
1o9r_A_1031o9r   A     TMNTRIS(HYDROXYMETHYL)AMINOMETHANE A - 142
1o9r_A_1031o9r   A     TMNTRIS(HYDROXYMETHYL)AMINOMETHANE R - 145
1o9r_A_1031o9r   A     FEFE (III) ION K - 149
1o9r_A_1031o9r   A     FEFE (III) ION W - 152
1umn_A_1111umn   A     EPE4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID E - 112
1umn_A_1111umn   A     EPE4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID E - 165
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1o9r_A_1031o9r   A AC7TMN BINDING SITE FOR CHAIN ED - 138

Clusters included in this Subclass
CLUSTER: HH.1.70
CLUSTER: HH.2.164
CLUSTER: HH.2.63
CLUSTER: HH.4.245
CLUSTER: HH.4.79