Information on SUBCLASS 8.3.1 |
Subclass Accession number: 2524
Subclass: 8.3.1 Type: HH alpha-alpha DB: ArchDB40 Image coordinates: Consensus coordinates: Conserved Annotation EC : 2.5 (>75 %) 2.5.1 (>75 %) 2.5.1.18 (>75 %) 2.7 (>75 %) 2.7.7 (>75 %) 2.7.7.74.3 (>50 %) 4.3.2 (>50 %) 4.3.2.1 GO : GO:0003887 (>75 %) GO:0004056 (>50 %) GO:0004364 (>75 %) GO:0004518 (>75 %) GO:0004527 (>75 %) GO:0016765 (>75 %) GO:0016772 (>75 %) GO:0016779 (>75 %) GO:0016788 (>75 %) GO:0016829 (>50 %) GO:0016840 (>50 %) GO:0016842 (>50 %) SCOP : 47615 (>75 %) 47616 (>75 %) 47617 (>75 %) 48556 (>50 %) 48557 (>50 %) 48558 (>50 %) 56671 (>50 %) 56672 (>50 %) 56673 (>50 %) |
Number of loops: 6 Average sequence ID (%) : 25.8 +/- 30.3 Average RMSD (Å) : 0.950 +/- 0.485 Consensus geometry
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Consensus Sequence: | hhXhXXppVphX |
(φψ)-conformation: | aalbpaaappaa |
Pattern: | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Conservation: | -1.545 | 0.129 | 2.074 | -0.863 | -1.064 | -0.795 | 0.049 | 0.810 | -0.477 | 0.851 | -1.068 | 1.055 | 0.613 | 1.260 | 1.666 | -0.141 | -1.561 | -0.543 | 0.129 | 0.230 | -0.265 | -0.543 |
Loops included in this Subclass |
Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
1bgx_T_638 | 1bgx | T | 641 | 662 | ETASWMFGVPREAVDPLMRRAA | HHHHHHHT--TTS--TTHHHHH | aaaaaaavbxaaaxxaaaaaaa |
1doi_*_8 | 1doi | - | 8 | 29 | YEVVDDNGWDMYDDDVFGEASD | HHHHHHHT--TTTS-HHHHHHH | aaaaaaavxbaaaxxaaaaaaa |
1kfs_A_733 | 1kfs | A | 736 | 757 | ATAAEVFGLPLETVTSEQRRSA | HHHHHHTT--TTT--HHHHHHH | aaaaaaalbxaaapxaaaaaaa |
1nk4_A_681 | 1nk4 | A | 684 | 705 | KTAMDIFQVSEDEVTPNMRRQA | HHHHHHTT--GGG--HHHHHHH | aaaaaaalbxaaaxxaaaaaaa |
1qtm_A_638 | 1qtm | A | 641 | 662 | ETASWMFGVPREAVDPLMRRAA | HHHHHHHT--GGG--HHHHHHH | aaaaaaavbpaaaxxaaaaaaa |
1s3e_A_159 | 1s3e | A | 167 | 188 | LFVNLCVTAETHEVSALWFLWY | HHHHHHHSS-TTTSBHHHHHHH | aaaaaaalbxaaabxaaaaaaa |
PDB ligands within a cut-off distance of 6 Å in this subclass |
Loop | PDB | Chain | Ligands | Residue |
1qtm_A_638 | 1qtm | A | TTPTHYMIDINE-5'-TRIPHOSPHATE | H - 639 |
1qtm_A_638 | 1qtm | A | TTPTHYMIDINE-5'-TRIPHOSPHATE | R - 659 |
1qtm_A_638 | 1qtm | A | 2DT3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE | R - 660 |
1qtm_A_638 | 1qtm | A | TTPTHYMIDINE-5'-TRIPHOSPHATE | R - 660 |
1qtm_A_638 | 1qtm | A | 2DT3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE | K - 663 |
1qtm_A_638 | 1qtm | A | MGMAGNESIUM ION | K - 663 |
1qtm_A_638 | 1qtm | A | TTPTHYMIDINE-5'-TRIPHOSPHATE | K - 663 |
1qtm_A_638 | 1qtm | A | 2DT3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE | T - 664 |
1qtm_A_638 | 1qtm | A | TTPTHYMIDINE-5'-TRIPHOSPHATE | T - 664 |
1qtm_A_638 | 1qtm | A | TTPTHYMIDINE-5'-TRIPHOSPHATE | F - 667 |
1s3e_A_159 | 1s3e | A | RHP(3R)-3-(PROP-2-YNYLAMINO)INDAN-5-OL | F - 168 |
1s3e_A_159 | 1s3e | A | RHP(3R)-3-(PROP-2-YNYLAMINO)INDAN-5-OL | L - 171 |
1s3e_A_159 | 1s3e | A | RHP(3R)-3-(PROP-2-YNYLAMINO)INDAN-5-OL | C - 172 |
1s3e_A_159 | 1s3e | A | RHP(3R)-3-(PROP-2-YNYLAMINO)INDAN-5-OL | V - 173 |
1s3e_A_159 | 1s3e | A | RHP(3R)-3-(PROP-2-YNYLAMINO)INDAN-5-OL | Y - 188 |
Clusters included in this Subclass |
CLUSTER: HH.8.9 |
CLUSTER: HH.9.5 |