ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 3.37.1

Subclass Accession number: 3012
Subclass: 3.37.1

Type: EH beta-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Number of loops: 6

Average sequence ID (%) : 34.4 +/- 23.2
Average RMSD (Å) : 0.400 +/- 0.141

Consensus geometry

d (Å): 9

delta (°): 45-90

theta (°): 135-180

rho (°): 90-135

Consensus Sequence:	IhGhGph
(φψ)-conformation:	bbSpbaa

Pattern:	[gknr]	[IVY]	[AGL]	[IV]	[ilv]	[G]	[lvy]	[G]	[gknt]	[CILVY]	[AG]	x	[anrst]
Conservation:	-0.740	0.134	-0.368	0.811	-0.427	1.952	-0.642	1.952	-0.790	-0.431	0.298	-0.866	-0.882

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1b7g_O_2	1b7g	O	3	15	NVAVNGYGTIGKR	EEEEE--SHHHHH	xbxbxSxbaaaaa
1gr0_A_16	1gr0	A	17	29	RVAIVGVGNCASS	EEEEE--SHHHHH	xbbbbvxbaaaaa
1h2b_A_189	1h2b	A	189	201	YVAIVGVGGLGHI	EEEEE--SHHHHH	bbxbbSxbaaaaa
1h6d_A_84	1h6d	A	85	97	GYAIVGLGKYALN	EEEEE--SHHHHH	xbbxbvxbaaaaa
1hyh_A_23	1hyh	A	23	35	KIGIIGLGNVGAA	EEEEE--SHHHHH	bbbbbSxbaaaaa
1vjp_A_2	1vjp	A	3	15	KVLILGQGYVAST	EEEEE--SHHHHH	xbbbbvxbaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1gr0_A_16	1gr0	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	V - 21
1gr0_A_16	1gr0	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	G - 22
1gr0_A_16	1gr0	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	V - 23
1gr0_A_16	1gr0	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	G - 24
1gr0_A_16	1gr0	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	N - 25
1gr0_A_16	1gr0	A	ZNZINC ION	N - 25
1gr0_A_16	1gr0	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	C - 26
1gr0_A_16	1gr0	A	ZNZINC ION	C - 26
1gr0_A_16	1gr0	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	A - 27
1h2b_A_189	1h2b	A	NAJNICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM)	V - 193
1h2b_A_189	1h2b	A	NAJNICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM)	G - 194
1h2b_A_189	1h2b	A	NAJNICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM)	V - 195
1h2b_A_189	1h2b	A	NAJNICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM)	G - 196
1h2b_A_189	1h2b	A	NAJNICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM)	G - 197
1h2b_A_189	1h2b	A	NAJNICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM)	L - 198
1h2b_A_189	1h2b	A	ZNZINC ION	L - 198
1h2b_A_189	1h2b	A	NAJNICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM)	G - 199
1h6d_A_84	1h6d	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	V - 89
1h6d_A_84	1h6d	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	G - 90
1h6d_A_84	1h6d	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	L - 91
1h6d_A_84	1h6d	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	G - 92
1h6d_A_84	1h6d	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	K - 93
1h6d_A_84	1h6d	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	Y - 94
1h6d_A_84	1h6d	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	A - 95
1hyh_A_23	1hyh	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	I - 27
1hyh_A_23	1hyh	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	G - 28
1hyh_A_23	1hyh	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	L - 29
1hyh_A_23	1hyh	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	G - 30
1hyh_A_23	1hyh	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	N - 31
1hyh_A_23	1hyh	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	V - 32
1hyh_A_23	1hyh	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	G - 33
1vjp_A_2	1vjp	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	L - 7
1vjp_A_2	1vjp	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	G - 8
1vjp_A_2	1vjp	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	Q - 9
1vjp_A_2	1vjp	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	G - 10
1vjp_A_2	1vjp	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	Y - 11
1vjp_A_2	1vjp	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	V - 12
1vjp_A_2	1vjp	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	A - 13

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1h2b_A_189	1h2b	A	NJ1COFACTOR BINDING SITE FOR CHAIN A	G - 197
1h6d_A_84	1h6d	A	AC1NDP BINDING SITE FOR CHAIN A	G - 90
1h6d_A_84	1h6d	A	AC1NDP BINDING SITE FOR CHAIN A	L - 91
1h6d_A_84	1h6d	A	AC1NDP BINDING SITE FOR CHAIN A	G - 92
1h6d_A_84	1h6d	A	AC1NDP BINDING SITE FOR CHAIN A	K - 93
1h6d_A_84	1h6d	A	AC1NDP BINDING SITE FOR CHAIN A	Y - 94

Clusters included in this Subclass

CLUSTER: EH.3.280

CLUSTER: EH.4.161