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Information on SUBCLASS 5.5.2
Subclass Accession number: 3215
Subclass: 5.5.2 PSSM
Type: EH beta-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 15

Average sequence ID (%) : 33.7 +/- 23.6
Average RMSD (Å) : 0.313 +/- 0.119

Consensus geometry
d (Å): 11 delta (°): 90-135 theta (°): 135-180 rho (°): 135-180
Consensus Sequence: hGXXXXGKp
(φψ)-conformation: bepplagaa
Pattern: [AFILV][AILMV][iltvy][GS]xx[adgnr][acitv][G][KM][GST][cesty]x[acgilmtv]
Conservation:-0.2080.232-0.4561.578-1.055-1.052-0.455-0.5102.3001.0780.248-0.492-0.472-0.735
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1e4y_A_21e4y   A417ILLGALVAGKGTQAEEEESTTSSHHHHHbbbexpvagaaaaa
1e6c_A_61e6c   A619FMVGARGCGMTTVGEEEES-TTSSHHHHxbbexxvavaaaaa
1f5n_A_381f5n   A4255AIVGLYRTGKSYLMEEEEBTTSSHHHHHbbbepxvavaaaaa
1fp6_A_31fp6   A619AIYGKGGIGKSTTTEEEESTTSSHHHHHbbbexxvagaaaaa
1huq_A_201huq   A2538VLLGESAVGKSSLVEEEESTTSSHHHHHbbbepxvagaaaaa
1i6i_A_911i6i   A94107FAYGQTGAGKSYTMEEEESTTSSHHHHHbbbexpvagaaaaa
1jny_A_61jny   A1023IVIGHVDHGKSTLVEEEESTTSSHHHHHbbbexpvagaaaaa
1ko7_A_1451ko7   A148161LITGDSGIGKSETAEEEESTTSSHHHHHbxbexpvagaaaaa
1nlf_A_321nlf   A3447ALVSPGGAGKSMLAEEEESTTSSHHHHHbbbewxvagaaaaa
1nn5_A_81nn5   A1023VLEGVDRAGKSTQSEEEESTTSSHHHHHbbbexpvagaaaaa
1puj_A_1211puj   A124137LIIGIPNVGKSTLIEEEESTTSSHHHHHbxbexpvagaaaaa
1q0b_A_981q0b   A102115FAYGQTGTGKTFTMEEEE-TTSSHHHHHbbbexpvagaaaaa
1qf9_A_71qf9   A1023FVLGGPGSGKGTQCEEEESTTSSHHHHHxbbexpvagaaaaa
1ryh_A_21ryh   A720VVVGDGAVGKTCLLEEEE-TTSSHHHHHbbbeppvagaaaaa
4tmk_A_54tmk   A720VIEGLEGAGKTTAREEEE-TTS-HHHHHbbbexxvavaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1e4y_A_21e4y   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 7
1e4y_A_21e4y   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE A - 8
1e4y_A_21e4y   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE L - 9
1e4y_A_21e4y   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE V - 10
1e4y_A_21e4y   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE A - 11
1e4y_A_21e4y   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 12
1e4y_A_21e4y   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE K - 13
1e4y_A_21e4y   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 14
1e4y_A_21e4y   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE T - 15
1e4y_A_21e4y   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE Q - 16
1e6c_A_61e6c   A     PO4PHOSPHATE ION A - 10
1e6c_A_61e6c   A     MPD2-METHYL-2,4-PENTANEDIOL A - 10
1e6c_A_61e6c   A     PO4PHOSPHATE ION R - 11
1e6c_A_61e6c   A     MPD2-METHYL-2,4-PENTANEDIOL R - 11
1e6c_A_61e6c   A     PO4PHOSPHATE ION G - 12
1e6c_A_61e6c   A     MPD2-METHYL-2,4-PENTANEDIOL G - 12
1e6c_A_61e6c   A     PO4PHOSPHATE ION C - 13
1e6c_A_61e6c   A     MPD2-METHYL-2,4-PENTANEDIOL C - 13
1e6c_A_61e6c   A     PO4PHOSPHATE ION G - 14
1e6c_A_61e6c   A     PO4PHOSPHATE ION M - 15
1e6c_A_61e6c   A     PO4PHOSPHATE ION T - 16
1e6c_A_61e6c   A     PO4PHOSPHATE ION T - 17
1f5n_A_381f5n   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER G - 45
1f5n_A_381f5n   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER L - 46
1f5n_A_381f5n   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER Y - 47
1f5n_A_381f5n   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER R - 48
1f5n_A_381f5n   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER T - 49
1f5n_A_381f5n   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER G - 50
1f5n_A_381f5n   A     MGMAGNESIUM ION K - 51
1f5n_A_381f5n   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER K - 51
1f5n_A_381f5n   A     MGMAGNESIUM ION S - 52
1f5n_A_381f5n   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER S - 52
1f5n_A_381f5n   A     MGMAGNESIUM ION Y - 53
1f5n_A_381f5n   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER Y - 53
1f5n_A_381f5n   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER L - 54
1fp6_A_31fp6   A     ADPADENOSINE-5'-DIPHOSPHATE G - 9
1fp6_A_31fp6   A     ADPADENOSINE-5'-DIPHOSPHATE K - 10
1fp6_A_31fp6   A     ADPADENOSINE-5'-DIPHOSPHATE G - 11
1fp6_A_31fp6   A     ADPADENOSINE-5'-DIPHOSPHATE G - 12
1fp6_A_31fp6   A     ADPADENOSINE-5'-DIPHOSPHATE I - 13
1fp6_A_31fp6   A     ADPADENOSINE-5'-DIPHOSPHATE G - 14
1fp6_A_31fp6   A     MGMAGNESIUM ION K - 15
1fp6_A_31fp6   A     ADPADENOSINE-5'-DIPHOSPHATE K - 15
1fp6_A_31fp6   A     MGMAGNESIUM ION S - 16
1fp6_A_31fp6   A     ADPADENOSINE-5'-DIPHOSPHATE S - 16
1fp6_A_31fp6   A     MGMAGNESIUM ION T - 17
1fp6_A_31fp6   A     ADPADENOSINE-5'-DIPHOSPHATE T - 17
1fp6_A_31fp6   A     ADPADENOSINE-5'-DIPHOSPHATE T - 18
1huq_A_201huq   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER G - 28
1huq_A_201huq   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER E - 29
1huq_A_201huq   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER S - 30
1huq_A_201huq   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER A - 31
1huq_A_201huq   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER V - 32
1huq_A_201huq   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER G - 33
1huq_A_201huq   A     MGMAGNESIUM ION K - 34
1huq_A_201huq   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER K - 34
1huq_A_201huq   A     MGMAGNESIUM ION S - 35
1huq_A_201huq   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER S - 35
1huq_A_201huq   A     MGMAGNESIUM ION S - 36
1huq_A_201huq   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER S - 36
1huq_A_201huq   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER L - 37
1i6i_A_911i6i   A     ACPPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER G - 97
1i6i_A_911i6i   A     ACPPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER Q - 98
1i6i_A_911i6i   A     ACPPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER T - 99
1i6i_A_911i6i   A     ACPPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER G - 100
1i6i_A_911i6i   A     ACPPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER A - 101
1i6i_A_911i6i   A     ACPPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER G - 102
1i6i_A_911i6i   A     MGMAGNESIUM ION K - 103
1i6i_A_911i6i   A     ACPPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER K - 103
1i6i_A_911i6i   A     MGMAGNESIUM ION S - 104
1i6i_A_911i6i   A     ACPPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER S - 104
1i6i_A_911i6i   A     MGMAGNESIUM ION Y - 105
1i6i_A_911i6i   A     ACPPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER Y - 105
1i6i_A_911i6i   A     ACPPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER T - 106
1jny_A_61jny   A     GDPGUANOSINE-5'-DIPHOSPHATE G - 13
1jny_A_61jny   A     GDPGUANOSINE-5'-DIPHOSPHATE H - 14
1jny_A_61jny   A     GDPGUANOSINE-5'-DIPHOSPHATE V - 15
1jny_A_61jny   A     GDPGUANOSINE-5'-DIPHOSPHATE D - 16
1jny_A_61jny   A     GDPGUANOSINE-5'-DIPHOSPHATE H - 17
1jny_A_61jny   A     GDPGUANOSINE-5'-DIPHOSPHATE G - 18
1jny_A_61jny   A     GDPGUANOSINE-5'-DIPHOSPHATE K - 19
1jny_A_61jny   A     GDPGUANOSINE-5'-DIPHOSPHATE S - 20
1jny_A_61jny   A     GDPGUANOSINE-5'-DIPHOSPHATE T - 21
1jny_A_61jny   A     GDPGUANOSINE-5'-DIPHOSPHATE L - 22
1ko7_A_1451ko7   A     PO4PHOSPHATE ION G - 151
1ko7_A_1451ko7   A     PO4PHOSPHATE ION D - 152
1ko7_A_1451ko7   A     PO4PHOSPHATE ION S - 153
1ko7_A_1451ko7   A     PO4PHOSPHATE ION G - 154
1ko7_A_1451ko7   A     PO4PHOSPHATE ION I - 155
1ko7_A_1451ko7   A     PO4PHOSPHATE ION G - 156
1ko7_A_1451ko7   A     PO4PHOSPHATE ION K - 157
1ko7_A_1451ko7   A     PO4PHOSPHATE ION S - 158
1ko7_A_1451ko7   A     PO4PHOSPHATE ION E - 159
1nn5_A_81nn5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER G - 13
1nn5_A_81nn5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER V - 14
1nn5_A_81nn5   A     2DT3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE D - 15
1nn5_A_81nn5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER D - 15
1nn5_A_81nn5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER R - 16
1nn5_A_81nn5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER A - 17
1nn5_A_81nn5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER G - 18
1nn5_A_81nn5   A     MGMAGNESIUM ION K - 19
1nn5_A_81nn5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER K - 19
1nn5_A_81nn5   A     MGMAGNESIUM ION S - 20
1nn5_A_81nn5   A     2DT3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE S - 20
1nn5_A_81nn5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER S - 20
1nn5_A_81nn5   A     MGMAGNESIUM ION T - 21
1nn5_A_81nn5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER T - 21
1nn5_A_81nn5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER Q - 22
1nn5_A_81nn5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER R - 24
1puj_A_1211puj   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER G - 127
1puj_A_1211puj   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER I - 128
1puj_A_1211puj   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER P - 129
1puj_A_1211puj   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER N - 130
1puj_A_1211puj   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER V - 131
1puj_A_1211puj   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER G - 132
1puj_A_1211puj   A     MGMAGNESIUM ION K - 133
1puj_A_1211puj   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER K - 133
1puj_A_1211puj   A     MGMAGNESIUM ION S - 134
1puj_A_1211puj   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER S - 134
1puj_A_1211puj   A     MGMAGNESIUM ION T - 135
1puj_A_1211puj   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER T - 135
1puj_A_1211puj   A     GNPPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER L - 136
1q0b_A_981q0b   A     ADPADENOSINE-5'-DIPHOSPHATE G - 105
1q0b_A_981q0b   A     ADPADENOSINE-5'-DIPHOSPHATE Q - 106
1q0b_A_981q0b   A     ADPADENOSINE-5'-DIPHOSPHATE T - 107
1q0b_A_981q0b   A     ADPADENOSINE-5'-DIPHOSPHATE G - 108
1q0b_A_981q0b   A     ADPADENOSINE-5'-DIPHOSPHATE T - 109
1q0b_A_981q0b   A     ADPADENOSINE-5'-DIPHOSPHATE G - 110
1q0b_A_981q0b   A     MGMAGNESIUM ION K - 111
1q0b_A_981q0b   A     ADPADENOSINE-5'-DIPHOSPHATE K - 111
1q0b_A_981q0b   A     MGMAGNESIUM ION T - 112
1q0b_A_981q0b   A     ADPADENOSINE-5'-DIPHOSPHATE T - 112
1q0b_A_981q0b   A     MGMAGNESIUM ION F - 113
1q0b_A_981q0b   A     ADPADENOSINE-5'-DIPHOSPHATE F - 113
1q0b_A_981q0b   A     ADPADENOSINE-5'-DIPHOSPHATE T - 114
1q0b_A_981q0b   A     NATETHYL 4-(3-HYDROXYPHENYL)-6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE M - 115
1qf9_A_71qf9   A     ALFTETRAFLUOROALUMINATE ION G - 13
1qf9_A_71qf9   A     ADPADENOSINE-5'-DIPHOSPHATE G - 13
1qf9_A_71qf9   A     ALFTETRAFLUOROALUMINATE ION G - 14
1qf9_A_71qf9   A     ALFTETRAFLUOROALUMINATE ION P - 15
1qf9_A_71qf9   A     ADPADENOSINE-5'-DIPHOSPHATE P - 15
1qf9_A_71qf9   A     C5PCYTIDINE-5'-MONOPHOSPHATE P - 15
1qf9_A_71qf9   A     ALFTETRAFLUOROALUMINATE ION G - 16
1qf9_A_71qf9   A     ADPADENOSINE-5'-DIPHOSPHATE G - 16
1qf9_A_71qf9   A     C5PCYTIDINE-5'-MONOPHOSPHATE G - 16
1qf9_A_71qf9   A     ALFTETRAFLUOROALUMINATE ION S - 17
1qf9_A_71qf9   A     ADPADENOSINE-5'-DIPHOSPHATE S - 17
1qf9_A_71qf9   A     ADPADENOSINE-5'-DIPHOSPHATE G - 18
1qf9_A_71qf9   A     ALFTETRAFLUOROALUMINATE ION K - 19
1qf9_A_71qf9   A     ADPADENOSINE-5'-DIPHOSPHATE K - 19
1qf9_A_71qf9   A     C5PCYTIDINE-5'-MONOPHOSPHATE K - 19
1qf9_A_71qf9   A     ALFTETRAFLUOROALUMINATE ION G - 20
1qf9_A_71qf9   A     MGMAGNESIUM ION G - 20
1qf9_A_71qf9   A     ADPADENOSINE-5'-DIPHOSPHATE G - 20
1qf9_A_71qf9   A     ADPADENOSINE-5'-DIPHOSPHATE T - 21
1qf9_A_71qf9   A     ADPADENOSINE-5'-DIPHOSPHATE Q - 22
4tmk_A_54tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE G - 10
4tmk_A_54tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE L - 11
4tmk_A_54tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE E - 12
4tmk_A_54tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE G - 13
4tmk_A_54tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE A - 14
4tmk_A_54tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE G - 15
4tmk_A_54tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE K - 16
4tmk_A_54tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE T - 17
4tmk_A_54tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE T - 18
4tmk_A_54tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE A - 19
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1e4y_A_21e4y   A AC1AP5 BINDING SITE FOR CHAIN AA - 8
1e4y_A_21e4y   A AC1AP5 BINDING SITE FOR CHAIN AL - 9
1e4y_A_21e4y   A AC1AP5 BINDING SITE FOR CHAIN AA - 11
1e4y_A_21e4y   A AC1AP5 BINDING SITE FOR CHAIN AG - 12
1e4y_A_21e4y   A AC1AP5 BINDING SITE FOR CHAIN AK - 13
1e4y_A_21e4y   A AC1AP5 BINDING SITE FOR CHAIN AG - 14
1e4y_A_21e4y   A AC1AP5 BINDING SITE FOR CHAIN AT - 15
1e6c_A_61e6c   A POACHAIN A WALKER TYPE A MOTIF FORMING THE P-LOOP WHICH IS THE BINDING SITE FOR THE PHOSPHATES OF ATP.G - 9
1e6c_A_61e6c   A POACHAIN A WALKER TYPE A MOTIF FORMING THE P-LOOP WHICH IS THE BINDING SITE FOR THE PHOSPHATES OF ATP.M - 15
1e6c_A_61e6c   A POACHAIN A WALKER TYPE A MOTIF FORMING THE P-LOOP WHICH IS THE BINDING SITE FOR THE PHOSPHATES OF ATP.T - 16

Clusters included in this Subclass
CLUSTER: EH.5.31