Logo
Information on SUBCLASS 4.1.3
Subclass Accession number: 623
Subclass: 4.1.3 PSSM
Type: HA beta-beta hairpin
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
SCOP : 48726 (>75 %)  48727 (>75 %)  
 Number of loops: 39

Average sequence ID (%) : 9.6 +/- 12.3
Average RMSD (Å) : 0.536 +/- 0.251

Consensus geometry
d (Å): 5 delta (°): 45-90 theta (°): 135-180 rho (°): 270-315
Consensus Sequence: XpXXXXXX
(φψ)-conformation: bbaaalbb
Pattern: xxx[dehknsw]xxx[adegknqs]xxx
Conservation:-0.422-0.928-0.1751.731-0.218-0.6590.7481.6030.164-1.468-0.376
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
12as_A_23312as   A237247LVWNPVLEDAFEEEETTTTEEEbbxxaaalbxb
1acc_*_4581acc   -460470ATYNFENGRVREEEETTTTEEExbxbaaalbxb
1bik_*_391bik   -4252YFYNGTSMACEEEEETTTTEEEbbxbaaalbxb
1bun_B_201bun   B2333FYYKPSAKRCVEEEEGGGTEEEbbxbaaNlbbb
1byf_A_961byf   A97107VQIWSKYNLLDEEEETTTTEEEbbxxaaavbxb
1clc_*_941clc   -95105SMFDNDTKETVEEEETTTTEEExbxxaaalbxb
1cqx_A_1901cqx   A194204AIDVPALGLQQEEEETTTTEEEbbxbaaavbxb
1csn_*_251csn   -2838EGTNLLNNQQVEEEETTTTEEExbbxaaavxxb
1dqz_A_81dqz   A1222QVPSASMGRDIEEEETTTTEEEbbwbaaalbxx
1dtx_*_201dtx   -2333FYYNQKKKQCEEEEETTTTEEEbbxxaaavbxb
1dyp_A_861dyp   A93103TFWDGCNQQQVEEEEGGGTEEExbxxaaalbxb
1eaz_A_1941eaz   A199209VKQGAVMKNWKEEE-TTT--EEbbxxaaavxbb
1ekr_A_831ekr   A8898LQAEPEHNRVREEEEGGGTEEEbbxbaaalbbb
1g0u_J_971g0u   J102112GGYDKKKNKPEEEEETTTTEEEbbbxaaavbwb
1ih7_A_1331ih7   A137147THYDSIDDRFYEEEETTTTEEEbbxbaaalbbx
1ivw_A_3421ivw   A354364KHSDLWSGINYEEE-TTT--EEbbbxaaavxbb
1iyk_A_1491iyk   A159169TFKLNKSNKVIEEEETTTTEEEbbbbaaalbbb
1izn_A_861izn   A8696RFLDPRNKISFEEE-TTT-EEEbbbbaaavbbb
1jce_A_2231jce   A227237SGIDLSTGLPREEEETTTTEEEbbbxaaavbwb
1jjf_A_501jjf   A5565SYFSTATNSTREEEETTTTEEEbbxbaaalbxb
1khi_A_511khi   A5868ISTSAATGQHREEE-TTT--EEbbbxaaavxxb
1kth_A_181kth   A2131WYYDPNTKSCAEEEETTTTEEEbbxbaaalbxb
1m2r_A_511m2r   A5565EGINVNNNEKCEEEETTTTEEExbbxaaNvxxb
1mxg_A_1161mxg   A117127LEWNPFVGDYTEEEETTTTEEExbxbaaavbxb
1o6y_A_231o6y   A2737LARDLRLHRDVEEEETTTTEEExbbxaaalbxb
1oi2_A_2601oi2   A265275RFWDYQQGSWQEEEETTTTEEExbxxaaavbxb
1phk_*_311phk   -3545RCIHKPTCKEYEEEETTTTEEExbbxaaavxxb
1q3q_A_4771q3q   A477487IGIDVFEGKPAEEEETTTTEEExbxbaaalbwb
1q8y_A_1701q8y   A174184LAKDMVNNTHVEEEETTTTEEExbbxaaalbbb
1qwd_A_721qwd   A7787KGYNPDRGMWQEEEETTTTEEEbbbxaaavbxb
1r3c_A_361r3c   A4050AAFDTKTGLRVEEEETTTTEEExbbxaaavxxb
1ri6_A_2901ri6   A292302IAAGQKSHHISEEE-TTT-EEEbbbbaaalbbb
1rl2_A_751rl2   A8090IEYDPNRSANIEEEEGGGTEEEbbxbaaalbxb
1ug9_A_8561ug9   A856866TPGLPGTNINLEE-SGGG-EEEbpxpaaavbbb
1uir_A_2191uir   A224234KNHIPGFFLNFEEEEGGGTEEEbbxbaaalbxb
1utc_A_3031utc   A306316TAPHEATAGIIEEEETTTTEEEbbxxaaalxbb
1v3e_A_5411v3e   A549559EINHKSLNTLQEEEETTTTEEExbxbaaalbbb
1vhz_A_591vhz   A6474REYAVGTESYEEEEETTTTEEEbbxbaaalbxx
2ebn_*_412ebn   -4959INYDAANDKVFEEEETTTTEEEbbbbaaalbxb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
12as_A_23312as   A     AMPADENOSINE MONOPHOSPHATE I - 236
12as_A_23312as   A     AMPADENOSINE MONOPHOSPHATE E - 248
12as_A_23312as   A     AMPADENOSINE MONOPHOSPHATE L - 249
12as_A_23312as   A     AMPADENOSINE MONOPHOSPHATE S - 250
12as_A_23312as   A     AMPADENOSINE MONOPHOSPHATE S - 251
1bik_*_391bik   *     NAGN-ACETYL-D-GLUCOSAMINE F - 43
1bik_*_391bik   *     NAGN-ACETYL-D-GLUCOSAMINE N - 45
1bik_*_391bik   *     NAGN-ACETYL-D-GLUCOSAMINE G - 46
1bik_*_391bik   *     NAGN-ACETYL-D-GLUCOSAMINE T - 47
1bik_*_391bik   *     NAGN-ACETYL-D-GLUCOSAMINE S - 48
1bik_*_391bik   *     NAGN-ACETYL-D-GLUCOSAMINE E - 52
1byf_A_961byf   A     ZNZINC ION Q - 98
1byf_A_961byf   A     ACTACETATE ION Q - 98
1byf_A_961byf   A     GOLGLYCEROL Q - 98
1byf_A_961byf   A     CACALCIUM ION W - 100
1byf_A_961byf   A     ZNZINC ION W - 100
1byf_A_961byf   A     ACTACETATE ION W - 100
1byf_A_961byf   A     GOLGLYCEROL W - 100
1byf_A_961byf   A     ZNZINC ION S - 101
1byf_A_961byf   A     ACTACETATE ION S - 101
1byf_A_961byf   A     OC6CALCIUM ION, 6 WATERS COORDINATED L - 105
1byf_A_961byf   A     CACALCIUM ION D - 107
1byf_A_961byf   A     ACTACETATE ION D - 107
1byf_A_961byf   A     GOLGLYCEROL D - 107
1byf_A_961byf   A     CACALCIUM ION D - 108
1byf_A_961byf   A     GOLGLYCEROL D - 108
1byf_A_961byf   A     CACALCIUM ION V - 109
1byf_A_961byf   A     ACTACETATE ION V - 109
1byf_A_961byf   A     GOLGLYCEROL V - 109
1cqx_A_1901cqx   A     FADFLAVIN-ADENINE DINUCLEOTIDE Y - 190
1cqx_A_1901cqx   A     FADFLAVIN-ADENINE DINUCLEOTIDE Q - 204
1cqx_A_1901cqx   A     FADFLAVIN-ADENINE DINUCLEOTIDE R - 206
1cqx_A_1901cqx   A     FADFLAVIN-ADENINE DINUCLEOTIDE Q - 207
1cqx_A_1901cqx   A     FADFLAVIN-ADENINE DINUCLEOTIDE Y - 208
1cqx_A_1901cqx   A     FADFLAVIN-ADENINE DINUCLEOTIDE S - 209
1csn_*_251csn   *     ATPADENOSINE-5'-TRIPHOSPHATE V - 25
1csn_*_251csn   *     ATPADENOSINE-5'-TRIPHOSPHATE I - 26
1csn_*_251csn   *     ATPADENOSINE-5'-TRIPHOSPHATE A - 39
1csn_*_251csn   *     ATPADENOSINE-5'-TRIPHOSPHATE K - 41
1csn_*_251csn   *     ATPADENOSINE-5'-TRIPHOSPHATE E - 43
1dyp_A_861dyp   A     CDCADMIUM ION K - 86
1dyp_A_861dyp   A     CDCADMIUM ION E - 88
1eaz_A_1941eaz   A     CITCITRIC ACID K - 200
1eaz_A_1941eaz   A     CITCITRIC ACID Q - 201
1eaz_A_1941eaz   A     CITCITRIC ACID G - 202
1eaz_A_1941eaz   A     CITCITRIC ACID A - 203
1eaz_A_1941eaz   A     CITCITRIC ACID V - 204
1eaz_A_1941eaz   A     CITCITRIC ACID K - 209
1eaz_A_1941eaz   A     CITCITRIC ACID R - 211
1ivw_A_3421ivw   A     TPQ5-(2-CARBOXY-2-AMINOETHYL)-2-HYDROXY-1,4-BENZOQUINONE K - 354
1ivw_A_3421ivw   A     TPQ5-(2-CARBOXY-2-AMINOETHYL)-2-HYDROXY-1,4-BENZOQUINONE H - 355
1ivw_A_3421ivw   A     TPQ5-(2-CARBOXY-2-AMINOETHYL)-2-HYDROXY-1,4-BENZOQUINONE T - 377
1iyk_A_1491iyk   A     MYATETRADECANOYL-COA I - 153
1iyk_A_1491iyk   A     MYATETRADECANOYL-COA V - 172
1iyk_A_1491iyk   A     MYATETRADECANOYL-COA I - 174
1iyk_A_1491iyk   A     MYATETRADECANOYL-COA N - 175
1iyk_A_1491iyk   A     MIM[CYCLOHEXYLETHYL]-[[[[4-[2-METHYL-1-IMIDAZOLYL-BUTYL] PHENYL]ACETYL]-SERYL]-LYSINYL]-AMINE N - 175
1iyk_A_1491iyk   A     MYATETRADECANOYL-COA F - 176
1iyk_A_1491iyk   A     MIM[CYCLOHEXYLETHYL]-[[[[4-[2-METHYL-1-IMIDAZOLYL-BUTYL] PHENYL]ACETYL]-SERYL]-LYSINYL]-AMINE F - 176
1iyk_A_1491iyk   A     MYATETRADECANOYL-COA L - 177
1iyk_A_1491iyk   A     MYATETRADECANOYL-COA C - 178
1iyk_A_1491iyk   A     MYATETRADECANOYL-COA I - 179
1kth_A_181kth   A     PO4PHOSPHATE ION L - 19
1kth_A_181kth   A     PO4PHOSPHATE ION W - 21
1kth_A_181kth   A     PO4PHOSPHATE ION R - 32
1m2r_A_511m2r   A     MNY5,8-DI-AMINO-1,4-DIHYDROXY-ANTHRAQUINONE V - 53
1m2r_A_511m2r   A     MNY5,8-DI-AMINO-1,4-DIHYDROXY-ANTHRAQUINONE I - 66
1m2r_A_511m2r   A     MNY5,8-DI-AMINO-1,4-DIHYDROXY-ANTHRAQUINONE K - 68
1mxg_A_1161mxg   A     ACRACARBOSE E - 118
1mxg_A_1161mxg   A     ACRACARBOSE F - 122
1mxg_A_1161mxg   A     ACRACARBOSE T - 129
1mxg_A_1161mxg   A     ACRACARBOSE D - 130
1o6y_A_231o6y   A     ACPPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER S - 23
1o6y_A_231o6y   A     MGMAGNESIUM ION S - 23
1o6y_A_231o6y   A     ACPPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER E - 24
1o6y_A_231o6y   A     ACPPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER V - 25
1o6y_A_231o6y   A     ACPPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER A - 38
1o6y_A_231o6y   A     ACPPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER K - 40
1o6y_A_231o6y   A     MGMAGNESIUM ION K - 40
1phk_*_311phk   *     ATPADENOSINE-5'-TRIPHOSPHATE S - 31
1phk_*_311phk   *     ATPADENOSINE-5'-TRIPHOSPHATE V - 32
1phk_*_311phk   *     ATPADENOSINE-5'-TRIPHOSPHATE V - 33
1phk_*_311phk   *     ATPADENOSINE-5'-TRIPHOSPHATE A - 46
1phk_*_311phk   *     ATPADENOSINE-5'-TRIPHOSPHATE K - 48
1phk_*_311phk   *     MNMANGANESE (II) ION K - 48
1q3q_A_4771q3q   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER I - 479
1q3q_A_4771q3q   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER D - 480
1q3q_A_4771q3q   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER V - 481
1q3q_A_4771q3q   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER F - 482
1q8y_A_1701q8y   A     ADPADENOSINE-5'-DIPHOSPHATE S - 170
1q8y_A_1701q8y   A     ADPADENOSINE-5'-DIPHOSPHATE T - 171
1q8y_A_1701q8y   A     ADPADENOSINE-5'-DIPHOSPHATE V - 172
1q8y_A_1701q8y   A     ADPADENOSINE-5'-DIPHOSPHATE A - 185
1q8y_A_1701q8y   A     ADPADENOSINE-5'-DIPHOSPHATE K - 187
1rl2_A_751rl2   A     MSESELENOMETHIONINE G - 75
1rl2_A_751rl2   A     MSESELENOMETHIONINE R - 76
1rl2_A_751rl2   A     MSESELENOMETHIONINE V - 77
1rl2_A_751rl2   A     MSESELENOMETHIONINE A - 78
1rl2_A_751rl2   A     MSESELENOMETHIONINE Y - 95
1ug9_A_8561ug9   A     CACALCIUM ION N - 863
1v3e_A_5411v3e   A     NAGN-ACETYL-D-GLUCOSAMINE S - 554
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1byf_A_961byf   A CAACARBOHYDRATE BINDING CALCIUM SITED - 107
1byf_A_961byf   A CAACARBOHYDRATE BINDING CALCIUM SITED - 108
1eaz_A_1941eaz   A LBSLBS STANDS FOR LIPID BINDING SITE. CB ATOM RESPONSIBLE FOR THE NOVEL SPECIFICITY OF THIS DOMAIN. THE ALANINE AT A1024 (203) IN TAPP1, IN DAPP1 ID A GLY, WHICH CAN BIND BOTH (3,4)P2, AND (3,4,5) P3K - 200
1eaz_A_1941eaz   A LBSLBS STANDS FOR LIPID BINDING SITE. CB ATOM RESPONSIBLE FOR THE NOVEL SPECIFICITY OF THIS DOMAIN. THE ALANINE AT A1024 (203) IN TAPP1, IN DAPP1 ID A GLY, WHICH CAN BIND BOTH (3,4)P2, AND (3,4,5) P3G - 202
1eaz_A_1941eaz   A LBSLBS STANDS FOR LIPID BINDING SITE. CB ATOM RESPONSIBLE FOR THE NOVEL SPECIFICITY OF THIS DOMAIN. THE ALANINE AT A1024 (203) IN TAPP1, IN DAPP1 ID A GLY, WHICH CAN BIND BOTH (3,4)P2, AND (3,4,5) P3A - 203
1eaz_A_1941eaz   A LBSLBS STANDS FOR LIPID BINDING SITE. CB ATOM RESPONSIBLE FOR THE NOVEL SPECIFICITY OF THIS DOMAIN. THE ALANINE AT A1024 (203) IN TAPP1, IN DAPP1 ID A GLY, WHICH CAN BIND BOTH (3,4)P2, AND (3,4,5) P3R - 211
1o6y_A_231o6y   A MG2MG BINDING SITE FOR CHAIN AK - 40

Clusters included in this Subclass
CLUSTER: HA.3.28
CLUSTER: HA.3.84
CLUSTER: HA.4.22
CLUSTER: HA.5.101
CLUSTER: HA.5.14
CLUSTER: HA.5.141
CLUSTER: HA.5.149
CLUSTER: HA.6.99