Logo
Information on SUBCLASS 16.2.1
Subclass Accession number: 6937
Subclass: 16.2.1 PSSM
Type: AR beta-beta link
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 5

Average sequence ID (%) : 63.6 +/- 17.5
Average RMSD (Å) : 0.320 +/- 0.110

Consensus geometry
d (Å): 9 delta (°): 90-135 theta (°): 90-135 rho (°): 315-360
Consensus Sequence: hXXpHGDXpPFDGXcGhLAH
(φψ)-conformation: bbepagbabppaepeepabb
Pattern: [MV][I]x[F][AGV]x[AGKR]x[H][GR][D]x[STY][P][F][D][G][EKP][DGS][GN]x[L][A][H][A]
Conservation:-0.1600.206-1.0960.990-0.959-1.263-1.068-0.9061.774-0.4890.990-1.201-0.8901.3820.9900.9900.990-0.653-0.681-0.053-1.2870.2060.2061.7740.206
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1bqq_M_1781bqq   M178202MIFFAEGFHGDSTPFDGEGGFLAHAEEEEE-S-SSSS----SSSS--EEEbbbbbbexavbabxpaepeexabbb
1cxv_A_1421cxv   A143167MISFGTKEHGDFYPFDGPSGLLAHAEEEEE-SS-SSS----SSSS--EEExbbbbbexagbabxxaepeexabbb
1gkd_A_1661gkd   A167191VIQFGVAEHGDGYPFDGKDGLLAHAEEEEE-SS-SSS----SSSS--EEExbbbbbexaGxabxxaepeexabbb
1hfc_*_1591hfc   -160184MISFVRGDHRDNSPFDGPGGNLAHAEEEEE-SS-SSS----SSSS--EEEbbbbbbexavbabpxaepeexabbb
1hy7_A_1421hy7   A143167MISFAVREHGDFYPFDGPGNVLAHAEEEEE-SS-SSS----SSSS--EEExbbxbbexagbabxxaepeexabbb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1bqq_M_1781bqq   M     CACALCIUM ION M - 178
1bqq_M_1781bqq   M     ZNZINC ION F - 180
1bqq_M_1781bqq   M     ZNZINC ION H - 186
1bqq_M_1781bqq   M     ZNZINC ION D - 188
1bqq_M_1781bqq   M     ZNZINC ION S - 189
1bqq_M_1781bqq   M     ZNZINC ION T - 190
1bqq_M_1781bqq   M     CACALCIUM ION F - 192
1bqq_M_1781bqq   M     ZNZINC ION F - 192
1bqq_M_1781bqq   M     CACALCIUM ION D - 193
1bqq_M_1781bqq   M     CACALCIUM ION G - 194
1bqq_M_1781bqq   M     CACALCIUM ION E - 195
1bqq_M_1781bqq   M     CACALCIUM ION G - 196
1bqq_M_1781bqq   M     CACALCIUM ION G - 197
1bqq_M_1781bqq   M     CACALCIUM ION F - 198
1bqq_M_1781bqq   M     CACALCIUM ION L - 199
1bqq_M_1781bqq   M     ZNZINC ION A - 200
1bqq_M_1781bqq   M     ZNZINC ION H - 201
1cxv_A_1421cxv   A     CACALCIUM ION I - 142
1cxv_A_1421cxv   A     ZNZINC ION H - 151
1cxv_A_1421cxv   A     ZNZINC ION D - 153
1cxv_A_1421cxv   A     ZNZINC ION Y - 155
1cxv_A_1421cxv   A     CBP2-{4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-TETRAHYDRO -PYRAN-4-YL}-N-HYDROXY-ACETAMIDE Y - 155
1cxv_A_1421cxv   A     ZNZINC ION P - 156
1cxv_A_1421cxv   A     ZNZINC ION F - 157
1cxv_A_1421cxv   A     CACALCIUM ION F - 157
1cxv_A_1421cxv   A     CACALCIUM ION D - 158
1cxv_A_1421cxv   A     CACALCIUM ION G - 159
1cxv_A_1421cxv   A     CACALCIUM ION P - 160
1cxv_A_1421cxv   A     CACALCIUM ION S - 161
1cxv_A_1421cxv   A     CACALCIUM ION G - 162
1cxv_A_1421cxv   A     CBP2-{4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-TETRAHYDRO -PYRAN-4-YL}-N-HYDROXY-ACETAMIDE G - 162
1cxv_A_1421cxv   A     CACALCIUM ION L - 163
1cxv_A_1421cxv   A     CBP2-{4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-TETRAHYDRO -PYRAN-4-YL}-N-HYDROXY-ACETAMIDE L - 163
1cxv_A_1421cxv   A     CACALCIUM ION L - 164
1cxv_A_1421cxv   A     CBP2-{4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-TETRAHYDRO -PYRAN-4-YL}-N-HYDROXY-ACETAMIDE L - 164
1cxv_A_1421cxv   A     ZNZINC ION A - 165
1cxv_A_1421cxv   A     CBP2-{4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-TETRAHYDRO -PYRAN-4-YL}-N-HYDROXY-ACETAMIDE A - 165
1cxv_A_1421cxv   A     ZNZINC ION H - 166
1cxv_A_1421cxv   A     CBP2-{4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-TETRAHYDRO -PYRAN-4-YL}-N-HYDROXY-ACETAMIDE H - 166
1cxv_A_1421cxv   A     CBP2-{4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-TETRAHYDRO -PYRAN-4-YL}-N-HYDROXY-ACETAMIDE A - 167
1gkd_A_1661gkd   A     CACALCIUM ION I - 166
1gkd_A_1661gkd   A     CACALCIUM ION V - 167
1gkd_A_1661gkd   A     ZNZINC ION H - 175
1gkd_A_1661gkd   A     ZNZINC ION D - 177
1gkd_A_1661gkd   A     ZNZINC ION Y - 179
1gkd_A_1661gkd   A     CACALCIUM ION F - 181
1gkd_A_1661gkd   A     ZNZINC ION F - 181
1gkd_A_1661gkd   A     CACALCIUM ION D - 182
1gkd_A_1661gkd   A     CACALCIUM ION G - 183
1gkd_A_1661gkd   A     CACALCIUM ION K - 184
1gkd_A_1661gkd   A     CACALCIUM ION D - 185
1gkd_A_1661gkd   A     BUM2-AMINO-N,3,3-TRIMETHYLBUTANAMIDE D - 185
1gkd_A_1661gkd   A     CACALCIUM ION G - 186
1gkd_A_1661gkd   A     STN2-{[FORMYL(HYDROXY)AMINO]METHYL}-4-METHYLPENTANOIC ACID G - 186
1gkd_A_1661gkd   A     BUM2-AMINO-N,3,3-TRIMETHYLBUTANAMIDE G - 186
1gkd_A_1661gkd   A     CACALCIUM ION L - 187
1gkd_A_1661gkd   A     STN2-{[FORMYL(HYDROXY)AMINO]METHYL}-4-METHYLPENTANOIC ACID L - 187
1gkd_A_1661gkd   A     BUM2-AMINO-N,3,3-TRIMETHYLBUTANAMIDE L - 187
1gkd_A_1661gkd   A     CACALCIUM ION L - 188
1gkd_A_1661gkd   A     STN2-{[FORMYL(HYDROXY)AMINO]METHYL}-4-METHYLPENTANOIC ACID L - 188
1gkd_A_1661gkd   A     BUM2-AMINO-N,3,3-TRIMETHYLBUTANAMIDE L - 188
1gkd_A_1661gkd   A     CACALCIUM ION A - 189
1gkd_A_1661gkd   A     STN2-{[FORMYL(HYDROXY)AMINO]METHYL}-4-METHYLPENTANOIC ACID A - 189
1gkd_A_1661gkd   A     STN2-{[FORMYL(HYDROXY)AMINO]METHYL}-4-METHYLPENTANOIC ACID H - 190
1gkd_A_1661gkd   A     ZNZINC ION H - 190
1gkd_A_1661gkd   A     STN2-{[FORMYL(HYDROXY)AMINO]METHYL}-4-METHYLPENTANOIC ACID A - 191
1hfc_*_1591hfc   *     ZNZINC ION V - 164
1hfc_*_1591hfc   *     ZNZINC ION H - 168
1hfc_*_1591hfc   *     ZNZINC ION D - 170
1hfc_*_1591hfc   *     ZNZINC ION S - 172
1hfc_*_1591hfc   *     ZNZINC ION F - 174
1hfc_*_1591hfc   *     CACALCIUM ION F - 174
1hfc_*_1591hfc   *     CACALCIUM ION D - 175
1hfc_*_1591hfc   *     CACALCIUM ION G - 176
1hfc_*_1591hfc   *     CACALCIUM ION P - 177
1hfc_*_1591hfc   *     CACALCIUM ION G - 178
1hfc_*_1591hfc   *     HAP(N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL) PHENYLALANYL)METHYL AMINE G - 178
1hfc_*_1591hfc   *     CACALCIUM ION G - 179
1hfc_*_1591hfc   *     HAP(N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL) PHENYLALANYL)METHYL AMINE G - 179
1hfc_*_1591hfc   *     CACALCIUM ION N - 180
1hfc_*_1591hfc   *     HAP(N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL) PHENYLALANYL)METHYL AMINE N - 180
1hfc_*_1591hfc   *     CACALCIUM ION L - 181
1hfc_*_1591hfc   *     HAP(N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL) PHENYLALANYL)METHYL AMINE L - 181
1hfc_*_1591hfc   *     ZNZINC ION A - 182
1hfc_*_1591hfc   *     HAP(N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL) PHENYLALANYL)METHYL AMINE A - 182
1hfc_*_1591hfc   *     ZNZINC ION H - 183
1hfc_*_1591hfc   *     HAP(N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL) PHENYLALANYL)METHYL AMINE H - 183
1hfc_*_1591hfc   *     HAP(N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL) PHENYLALANYL)METHYL AMINE A - 184
1hy7_A_1421hy7   A     CACALCIUM ION M - 143
1hy7_A_1421hy7   A     ZNZINC ION A - 147
1hy7_A_1421hy7   A     CACALCIUM ION G - 161
1hy7_A_1421hy7   A     CACALCIUM ION N - 162
1hy7_A_1421hy7   A     CACALCIUM ION V - 163
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1gkd_A_1661gkd   A BUABUM BINDING SITE FOR CHAIN AG - 186

Clusters included in this Subclass
CLUSTER: AR.16.3