ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 5.6.1

Subclass Accession number: 7460
Subclass: 5.6.1

Type: EH beta-alpha
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Number of loops: 11

Average sequence ID (%) : 30.3 +/- 23.9
Average RMSD (Å) : 0.491 +/- 0.158

Consensus geometry

d (Å): 9

delta (°): 90-135

theta (°): 135-180

rho (°): 90-135

Consensus Sequence:	XhhhcXGKp
(φψ)-conformation:	bbpplagaa

Pattern:	[AGILMV]	[AFGILV]	[AILV]	x	[AFGT]	[gilpy]	[aps]	[AGKS]	[acsv]	[G]	[DKT]	[DGNST]	[agntv]	x	[ACILV]
Conservation:	-0.223	-0.640	0.516	-0.829	-0.159	-1.163	-0.088	0.411	-0.347	3.110	0.615	-0.112	-0.909	-0.040	-0.140

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1a5t_*_26	1a5t	-	27	41	LLIQALPGMGDDALI	EEEE--TTS-HHHHH	bbxbbxxvavaaaaa
1ak2_*_18	1ak2	-	19	33	AVLLGPPGAGKGTQA	EEEE--TTSSHHHHH	bbbbbxxvagaaaaa
1aky_*_6	1aky	-	7	21	MVLIGPPGAGKGTQA	EEEE--TTSSHHHHH	bbbbbxpvagaaaaa
1h8e_D_151	1h8e	D	152	166	IGLFGGAGVGKTVLI	EEEEESTTSSHHHHH	bbbxbxxvagaaaaa
1j99_A_37	1j99	A	37	51	VIILTYPKSGTNWLA	EEEE-STTSSHHHHH	bbxbbxpvagaaaaa
1khb_A_277	1khb	A	280	294	LAAAFPSACGKTNLA	EEEE--TTS-HHHHH	bbbbbxpUagaaaaa
1nks_A_2	1nks	A	4	18	GIVTGIPGVGKSTVL	EEEEE-TTS-HHHHH	bbxbbxpvavaaaaa
1pjr_*_27	1pjr	-	27	41	LLIMAGAGSGKTRVL	EEEEE-TTS-HHHHH	bbbxxxpvavaaaaa
1qhx_A_5	1qhx	A	6	20	IILNGGSSAGKSGIV	EEEE--TTSSHHHHH	bbxbbxxvagaaaaa
1uf9_A_9	1uf9	A	11	25	IGITGNIGSGKSTVA	EEEEE-TTS-HHHHH	bxbbbxpvavaaaaa
3adk_*_10	3adk	-	11	25	IFVVGGPGSGKGTQC	EEEEE-TTSSHHHHH	bxbbbxxvavaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1a5t_*_26	1a5t	*	ZNZINC ION	R - 46
1aky_*_6	1aky	*	AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE	G - 11
1aky_*_6	1aky	*	AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE	P - 12
1aky_*_6	1aky	*	AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE	P - 13
1aky_*_6	1aky	*	AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE	G - 14
1aky_*_6	1aky	*	IMDIMIDAZOLE	G - 14
1aky_*_6	1aky	*	AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE	A - 15
1aky_*_6	1aky	*	AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE	G - 16
1aky_*_6	1aky	*	AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE	K - 17
1aky_*_6	1aky	*	IMDIMIDAZOLE	K - 17
1aky_*_6	1aky	*	AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE	G - 18
1aky_*_6	1aky	*	IMDIMIDAZOLE	G - 18
1aky_*_6	1aky	*	AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE	T - 19
1aky_*_6	1aky	*	IMDIMIDAZOLE	T - 19
1aky_*_6	1aky	*	AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE	Q - 20
1aky_*_6	1aky	*	IMDIMIDAZOLE	A - 21
1h8e_D_151	1h8e	D	ADPADENOSINE-5'-DIPHOSPHATE	G - 156
1h8e_D_151	1h8e	D	ALFTETRAFLUOROALUMINATE ION	G - 156
1h8e_D_151	1h8e	D	ADPADENOSINE-5'-DIPHOSPHATE	G - 157
1h8e_D_151	1h8e	D	ALFTETRAFLUOROALUMINATE ION	G - 157
1h8e_D_151	1h8e	D	ADPADENOSINE-5'-DIPHOSPHATE	A - 158
1h8e_D_151	1h8e	D	ALFTETRAFLUOROALUMINATE ION	A - 158
1h8e_D_151	1h8e	D	ADPADENOSINE-5'-DIPHOSPHATE	G - 159
1h8e_D_151	1h8e	D	ALFTETRAFLUOROALUMINATE ION	G - 159
1h8e_D_151	1h8e	D	ADPADENOSINE-5'-DIPHOSPHATE	V - 160
1h8e_D_151	1h8e	D	ALFTETRAFLUOROALUMINATE ION	V - 160
1h8e_D_151	1h8e	D	ADPADENOSINE-5'-DIPHOSPHATE	G - 161
1h8e_D_151	1h8e	D	ADPADENOSINE-5'-DIPHOSPHATE	K - 162
1h8e_D_151	1h8e	D	MGMAGNESIUM ION	K - 162
1h8e_D_151	1h8e	D	ALFTETRAFLUOROALUMINATE ION	K - 162
1h8e_D_151	1h8e	D	ADPADENOSINE-5'-DIPHOSPHATE	T - 163
1h8e_D_151	1h8e	D	MGMAGNESIUM ION	T - 163
1h8e_D_151	1h8e	D	ALFTETRAFLUOROALUMINATE ION	T - 163
1h8e_D_151	1h8e	D	ADPADENOSINE-5'-DIPHOSPHATE	V - 164
1h8e_D_151	1h8e	D	MGMAGNESIUM ION	V - 164
1h8e_D_151	1h8e	D	ADPADENOSINE-5'-DIPHOSPHATE	L - 165
1j99_A_37	1j99	A	IODIODIDE ION	P - 43
1j99_A_37	1j99	A	AND3-BETA-HYDROXY-5-ANDROSTEN-17-ONE	P - 43
1j99_A_37	1j99	A	IODIODIDE ION	K - 44
1j99_A_37	1j99	A	AND3-BETA-HYDROXY-5-ANDROSTEN-17-ONE	K - 44
1j99_A_37	1j99	A	IODIODIDE ION	S - 45
1j99_A_37	1j99	A	IODIODIDE ION	G - 46
1j99_A_37	1j99	A	IODIODIDE ION	T - 47
1j99_A_37	1j99	A	AND3-BETA-HYDROXY-5-ANDROSTEN-17-ONE	T - 47
1j99_A_37	1j99	A	IODIODIDE ION	N - 48
1j99_A_37	1j99	A	HGIMERCURY (II) IODIDE	L - 54
1j99_A_37	1j99	A	HGIMERCURY (II) IODIDE	C - 55
1j99_A_37	1j99	A	HGIMERCURY (II) IODIDE	L - 56
1j99_A_37	1j99	A	HGIMERCURY (II) IODIDE	H - 58
1khb_A_277	1khb	A	GTOPHOSPHOMETHYLPHOSPHONIC ACID-GUANYLATE ESTER	F - 284
1khb_A_277	1khb	A	GTOPHOSPHOMETHYLPHOSPHONIC ACID-GUANYLATE ESTER	P - 285
1khb_A_277	1khb	A	MNMANGANESE (II) ION	S - 286
1khb_A_277	1khb	A	GTOPHOSPHOMETHYLPHOSPHONIC ACID-GUANYLATE ESTER	S - 286
1khb_A_277	1khb	A	GTOPHOSPHOMETHYLPHOSPHONIC ACID-GUANYLATE ESTER	A - 287
1khb_A_277	1khb	A	GTOPHOSPHOMETHYLPHOSPHONIC ACID-GUANYLATE ESTER	C - 288
1khb_A_277	1khb	A	GTOPHOSPHOMETHYLPHOSPHONIC ACID-GUANYLATE ESTER	G - 289
1khb_A_277	1khb	A	MNMANGANESE (II) ION	K - 290
1khb_A_277	1khb	A	GTOPHOSPHOMETHYLPHOSPHONIC ACID-GUANYLATE ESTER	K - 290
1khb_A_277	1khb	A	MNMANGANESE (II) ION	T - 291
1khb_A_277	1khb	A	GTOPHOSPHOMETHYLPHOSPHONIC ACID-GUANYLATE ESTER	T - 291
1khb_A_277	1khb	A	GTOPHOSPHOMETHYLPHOSPHONIC ACID-GUANYLATE ESTER	N - 292
1khb_A_277	1khb	A	GTOPHOSPHOMETHYLPHOSPHONIC ACID-GUANYLATE ESTER	L - 293
1qhx_A_5	1qhx	A	ATPADENOSINE-5'-TRIPHOSPHATE	G - 10
1qhx_A_5	1qhx	A	ATPADENOSINE-5'-TRIPHOSPHATE	G - 11
1qhx_A_5	1qhx	A	ATPADENOSINE-5'-TRIPHOSPHATE	S - 12
1qhx_A_5	1qhx	A	ATPADENOSINE-5'-TRIPHOSPHATE	S - 13
1qhx_A_5	1qhx	A	ATPADENOSINE-5'-TRIPHOSPHATE	A - 14
1qhx_A_5	1qhx	A	ATPADENOSINE-5'-TRIPHOSPHATE	G - 15
1qhx_A_5	1qhx	A	MGMAGNESIUM ION	K - 16
1qhx_A_5	1qhx	A	ATPADENOSINE-5'-TRIPHOSPHATE	K - 16
1qhx_A_5	1qhx	A	MGMAGNESIUM ION	S - 17
1qhx_A_5	1qhx	A	ATPADENOSINE-5'-TRIPHOSPHATE	S - 17
1qhx_A_5	1qhx	A	ATPADENOSINE-5'-TRIPHOSPHATE	G - 18
1qhx_A_5	1qhx	A	ATPADENOSINE-5'-TRIPHOSPHATE	I - 19
1qhx_A_5	1qhx	A	ATPADENOSINE-5'-TRIPHOSPHATE	R - 21
1uf9_A_9	1uf9	A	MSESELENOMETHIONINE	N - 16

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1h8e_D_151	1h8e	D	AC7ADP BINDING SITE FOR CHAIN D	G - 159
1h8e_D_151	1h8e	D	AC7ADP BINDING SITE FOR CHAIN D	G - 161
1h8e_D_151	1h8e	D	PLPLYSINE WITHIN THE P-LOOP (PHOSPHATE BINDING) MOTIF, GXXXXGKT/S.	K - 162
1h8e_D_151	1h8e	D	AC7ADP BINDING SITE FOR CHAIN D	T - 163

Clusters included in this Subclass

CLUSTER: EH.4.100

CLUSTER: EH.6.21