Information on SUBCLASS 4.6.1 |
Subclass Accession number: 8442
Subclass: 4.6.1 Type: HE alpha-beta DB: ArchDB-EC Image coordinates: Consensus coordinates: |
Number of loops: 18 Average sequence ID (%) : 21.2 +/- 21.2 Average RMSD (Å) : 0.783 +/- 0.172 Consensus geometry
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Consensus Sequence: | XXXPpXhX |
(φψ)-conformation: | aabaaabb |
Pattern: | [afilmvy] | x | x | [afilmvy] | [acklv] | x | [afklmtv] | x | [P] | [DEGKNQS] | x | [filvy] | x |
Conservation: | -0.319 | -0.611 | -0.477 | -0.077 | -0.184 | -0.404 | -0.535 | -0.370 | 3.196 | 0.372 | -0.354 | 0.172 | -0.406 |
Loops included in this Subclass |
Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
1aui_A_126 | 1aui | A | 133 | 145 | LWALKILYPKTLF | HHHHHHHSTTTEE | aaaaaaabaaabb |
1azw_A_111 | 1azw | A | 116 | 128 | ALAYAQTHPQQVT | HHHHHHH-GGGEE | aaaaaaabaaaba |
1cjw_A_67 | 1cjw | A | 70 | 82 | VQHFLTLCPELSL | HHHHHHH-GGGEE | aaaaaaabaaabb |
1cqz_A_334 | 1cqz | A | 339 | 351 | VWNMALFYPERVR | HHHHHHH--TTEE | aaaaaaabaaaba |
1cvl_*_89 | 1cvl | - | 93 | 105 | SRYVAAVAPQLVA | HHHHHHH-GGGEE | aaaaaaabaaaba |
1dtd_A_371 | 1dtd | A | 378 | 390 | MDNLVAEHPGLVS | HHHHHHH-TTTEE | aaaaaaabaaabb |
1ex9_A_84 | 1ex9 | A | 88 | 100 | IRYVAAVRPDLIA | HHHHHHH-GGGEE | aaaaaaabaaaba |
1f0n_A_127 | 1f0n | A | 132 | 144 | AMILAAYHPQQFI | HHHHHHH-TTTEE | aaaaaaabaaaba |
1fcj_A_118 | 1fcj | A | 126 | 138 | AEEIVASDPQKYL | HHHHHHTSTTTEE | aaaaaaabaaabb |
1fnb_*_213 | 1fnb | - | 216 | 228 | FEKMKEKAPDNFR | HHHHHHH-TTTEE | aaaaaaabaaabb |
1itu_A_78 | 1itu | A | 89 | 101 | VHRMCRMYPETFL | HHHHHHH-TTTEE | aaaaaaabaaaxb |
1jk7_A_100 | 1jk7 | A | 107 | 119 | LLAYKIKYPENFF | HHHHHHHSTTTEE | aaaaaaabaaabb |
1q44_A_205 | 1q44 | A | 212 | 224 | YWYASRENPNKVL | HHHHHHH-TTTEE | aaaaaaabaaabb |
1qfz_A_207 | 1qfz | A | 210 | 222 | FEKMKEKAPENFR | HHHHHHH-TTTEE | aaaaaaabaaabb |
1qtr_A_114 | 1qtr | A | 119 | 131 | ALAYAQTHPERVS | HHHHHTT-TTSEE | aaaaaaabaaaba |
1uf9_A_50 | 1uf9 | A | 50 | 62 | EEELKRLFPEAVV | HHHHHHH-GGGEE | aaaaaaabaaaxb |
2hgs_A_345 | 2hgs | A | 350 | 362 | AIAEALAAPSRFV | HHHHHHHSGGGEE | aaaaaaabaaabb |
4lip_D_88 | 4lip | D | 93 | 105 | SRYVAAVAPDLVA | HHHHHHH-GGGEE | aaaaaaabaaaba |
PDB ligands within a cut-off distance of 6 Å in this subclass |
Loop | PDB | Chain | Ligands | Residue |
1ex9_A_84 | 1ex9 | A | OCPOCTYL-PHOSPHINIC ACID 1,2-BIS-OCTYLCARBAMOYLOXY-ETHYL ESTER | G - 84 |
1f0n_A_127 | 1f0n | A | MPD2-METHYL-2,4-PENTANEDIOL | M - 127 |
1f0n_A_127 | 1f0n | A | MPD2-METHYL-2,4-PENTANEDIOL | A - 128 |
1f0n_A_127 | 1f0n | A | MPD2-METHYL-2,4-PENTANEDIOL | Y - 138 |
1f0n_A_127 | 1f0n | A | MPD2-METHYL-2,4-PENTANEDIOL | H - 139 |
1f0n_A_127 | 1f0n | A | MPD2-METHYL-2,4-PENTANEDIOL | P - 140 |
1f0n_A_127 | 1f0n | A | MPD2-METHYL-2,4-PENTANEDIOL | Q - 141 |
1f0n_A_127 | 1f0n | A | MPD2-METHYL-2,4-PENTANEDIOL | Q - 142 |
1f0n_A_127 | 1f0n | A | MPD2-METHYL-2,4-PENTANEDIOL | F - 143 |
1itu_A_78 | 1itu | A | NAGN-ACETYL-D-GLUCOSAMINE | M - 95 |
1itu_A_78 | 1itu | A | NAGN-ACETYL-D-GLUCOSAMINE | Y - 96 |
1qfz_A_207 | 1qfz | A | NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | A - 226 |
1qfz_A_207 | 1qfz | A | NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | V - 227 |
2hgs_A_345 | 2hgs | A | ADPADENOSINE-5'-DIPHOSPHATE | V - 362 |
2hgs_A_345 | 2hgs | A | ADPADENOSINE-5'-DIPHOSPHATE | K - 364 |
4lip_D_88 | 4lip | D | CCPBUTYLPHOSPHONATE | Q - 88 |
4lip_D_88 | 4lip | D | CCPBUTYLPHOSPHONATE | G - 89 |
PDB Site Annotated loops in this subclass |
Loop | PDB | Chain | Site | Residue |
4lip_D_88 | 4lip | D | OXDOXYANION HOLE | Q - 88 |
Clusters included in this Subclass |
CLUSTER: HE.3.49 |
CLUSTER: HE.4.174 |
CLUSTER: HE.4.204 |
CLUSTER: HE.4.70 |
CLUSTER: HE.5.292 |
CLUSTER: HE.5.39 |