ArchDB - Biological DataBase of Protein Loops

Grup de Recerca en Informàtica Biomèdica

Information on SUBCLASS 2.7.1

Subclass Accession number: 8966
Subclass: 2.7.1

PSSM

Type: HH alpha-alpha
DB: ArchDB-EC

Image coordinates:

Rasmol PDB

Jmol PDB

Consensus coordinates:

Rasmol PDB

Jmol PDB

Number of loops: 11

Average sequence ID (%) : 11.1 +/- 14.2
Average RMSD (Å) : 0.636 +/- 0.143

Consensus geometry

d (Å): 9

delta (°): 45-90

theta (°): 45-90

rho (°): 90-135

Consensus Sequence:	pXXchX
(φψ)-conformation:	aabbaa

Pattern:	x	x	[dehnqr]	x	[acfimtv]	[DENW]	[filpv]	[adekq]	[aekst]	[afilv]	[aenqr]	x
Conservation:	-1.178	-0.168	0.685	-0.604	0.091	2.809	-0.463	-0.602	0.093	-0.187	-0.480	0.006

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1feh_A_514	1feh	A	516	527	DLEKVDIKKVRA	HHHHS-HHHHHH	aaaabxaaaaaa
1gk9_A_63	1gk9	A	69	80	IRRNYWPDAIRA	HHHT--HHHHHH	aaaabbaaaaaa
1itx_A_256	1itx	A	258	269	YAANTELAKIAA	HHHTS-HHHHHH	aaaabbaaaaaa
1jqn_A_758	1jqn	A	770	781	VFAKADLWLAEY	HHHH--HHHHHH	aaaaxbaaaaaa
1jv1_A_27	1jv1	A	36	47	ELQAMNFEELNF	HHHT--HHHHHH	aaaaxbaaaaaa
1khc_A_290	1khc	A	290	301	FSQHFNLATFNK	HHHH--HHHHHH	aaaaxbaaaaaa
1ld8_B_666	1ld8	B	668	679	AYDIINREKLLQ	HHHHS-HHHHHH	aaaaxxaaaaaa
1msw_D_821	1msw	D	835	846	TYESCDVLADFY	HHHH--HHHHHH	aaaabxaaaaaa
1n8i_A_545	1n8i	A	554	565	HYHQVDVAAVQQ	HHHHS-HHHHHH	aaaabxaaaaaa
1p7t_A_538	1p7t	A	547	558	HYHQTNVQSVQA	HHHHS-HHHHHH	aaaabxaaaaaa
5csm_A_185	5csm	A	189	200	MKNITNSAVEEK	HHHT--HHHHHH	aaaabbaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1jqn_A_758	1jqn	A	ASPASPARTIC ACID	M - 769
1jqn_A_758	1jqn	A	ASPASPARTIC ACID	K - 773
1khc_A_290	1khc	A	UNXUNKNOWN ATOM OR ION	F - 290
1khc_A_290	1khc	A	UNXUNKNOWN ATOM OR ION	S - 291
1khc_A_290	1khc	A	UNXUNKNOWN ATOM OR ION	Q - 292
1khc_A_290	1khc	A	UNXUNKNOWN ATOM OR ION	L - 296
1khc_A_290	1khc	A	UNXUNKNOWN ATOM OR ION	A - 297
1khc_A_290	1khc	A	UNXUNKNOWN ATOM OR ION	N - 300
1p7t_A_538	1p7t	A	ACOACETYL COENZYME *A	P - 538
1p7t_A_538	1p7t	A	PEGDI(HYDROXYETHYL)ETHER	Y - 548
1p7t_A_538	1p7t	A	PEGDI(HYDROXYETHYL)ETHER	N - 552
1p7t_A_538	1p7t	A	PEGDI(HYDROXYETHYL)ETHER	V - 553
1p7t_A_538	1p7t	A	PEGDI(HYDROXYETHYL)ETHER	Q - 554
1p7t_A_538	1p7t	A	PEGDI(HYDROXYETHYL)ETHER	S - 555
1p7t_A_538	1p7t	A	PEGDI(HYDROXYETHYL)ETHER	Q - 557

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
5csm_A_185	5csm	A	ACTACTIVE SITE.	N - 194
5csm_A_185	5csm	A	ACTACTIVE SITE.	V - 197
5csm_A_185	5csm	A	ACTACTIVE SITE.	E - 198

Clusters included in this Subclass

CLUSTER: HH.1.51

CLUSTER: HH.2.50

CLUSTER: HH.3.65