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Information on 1cvs
PDB: 1cvs
Compound: fibroblast growth factor 2
Classification: GROWTH FACTOR/GROWTH FACTOR RECEPTOR
Entry date in PDB: 2000-01-28
Resolution [Å]: 2.80
R-Factor: 0.240


CHAIN: A
SWISS-PROT/TREMBL: P09038
   KEYWORD: 3D-structure    Angiogenesis    Growth factor    Heparin-binding    Mitogen   
SCOP: b.42.1.1 All beta proteins    beta-Trefoil    Cytokine    Fibroblast growth factors (FGF)    Basic FGF (FGF2)    Human (Homo sapiens)
GO:  growth factor activity   


CHAIN: B
SWISS-PROT/TREMBL: P09038
   KEYWORD: 3D-structure    Angiogenesis    Growth factor    Heparin-binding    Mitogen   
SCOP: b.42.1.1 All beta proteins    beta-Trefoil    Cytokine    Fibroblast growth factors (FGF)    Basic FGF (FGF2)    Human (Homo sapiens)
GO:  growth factor activity   


CHAIN: C
SWISS-PROT/TREMBL: P11362
   KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Chromosomal translocation    Disease mutation    Glycoprotein    Immunoglobulin domain    Phosphorylation    Receptor    Repeat    Signal    Transferase    Transmembrane    Tyrosine-protein kinase   
EC: 2.7.1.112
SCOP: b.1.1.4 All beta proteins    Immunoglobulin-like beta-sandwich    Immunoglobulin    I set domains    Fibroblast growth factor receptor, FGFR    Human (Homo sapiens), FGFR1
SCOP: b.1.1.4 All beta proteins    Immunoglobulin-like beta-sandwich    Immunoglobulin    I set domains    Fibroblast growth factor receptor, FGFR    Human (Homo sapiens), FGFR1
GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    protein amino acid phosphorylation   


CHAIN: D
SWISS-PROT/TREMBL: P11362
   KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Chromosomal translocation    Disease mutation    Glycoprotein    Immunoglobulin domain    Phosphorylation    Receptor    Repeat    Signal    Transferase    Transmembrane    Tyrosine-protein kinase   
EC: 2.7.1.112
SCOP: b.1.1.4 All beta proteins    Immunoglobulin-like beta-sandwich    Immunoglobulin    I set domains    Fibroblast growth factor receptor, FGFR    Human (Homo sapiens), FGFR1
SCOP: b.1.1.4 All beta proteins    Immunoglobulin-like beta-sandwich    Immunoglobulin    I set domains    Fibroblast growth factor receptor, FGFR    Human (Homo sapiens), FGFR1
GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    protein amino acid phosphorylation   
1cvs Image
Image Source: PDB

Stored Loops of 1cvs

Loops in ArchDB-EC clusters

1cvs_C_320 - HE => SUBCLASS : 0.1.17

Loops not clustered in ArchDB

1cvs_C_273 - AR
1cvs_C_237 - AR
1cvs_C_279 - AR
1cvs_C_214 - AR
1cvs_C_265 - AR
1cvs_C_195 - AR
1cvs_C_325 - AR
1cvs_C_180 - AR
1cvs_C_174 - AR
1cvs_C_165 - AR
1cvs_C_151 - AR
1cvs_C_256 - AR
1cvs_C_307 - EH
1cvs_C_286 - HA
1cvs_C_226 - HA
1cvs_C_207 - HA
1cvs_C_187 - HA
1cvs_C_337 - HA

Homologous structures to 1cvs classified in ArchDB

1bfg - - percentage of sequence identity: 100
1cvs C - percentage of sequence identity: 100
1cvs D - percentage of sequence identity: 100
1djs A - percentage of sequence identity: 79
1e0o B - percentage of sequence identity: 79
1e0o D - percentage of sequence identity: 79
1ev2 E - percentage of sequence identity: 79
1ev2 F - percentage of sequence identity: 79
1ev2 G - percentage of sequence identity: 79
1ev2 H - percentage of sequence identity: 79
1evt C - percentage of sequence identity: 99
1evt D - percentage of sequence identity: 99
1fq9 C - percentage of sequence identity: 100
1fq9 D - percentage of sequence identity: 100
1ii4 E - percentage of sequence identity: 78
1ii4 F - percentage of sequence identity: 78
1ii4 G - percentage of sequence identity: 78
1ii4 H - percentage of sequence identity: 78
1iil E - percentage of sequence identity: 78
1iil F - percentage of sequence identity: 78
1iil G - percentage of sequence identity: 78
1iil H - percentage of sequence identity: 78
1nun B - percentage of sequence identity: 71
1ry7 B - percentage of sequence identity: 74
1wvz A - percentage of sequence identity: 80
2fdb P - percentage of sequence identity: 78
2fdb R - percentage of sequence identity: 78