PDB: 1h4w Compound: trypsin iva Classification: HYDROLASE Entry date in PDB: 2002-02-11 Resolution [Å]: 1.70 R-Factor: 0.188

CHAIN: A SWISS-PROT/TREMBL: P35030    KEYWORD: 3D-structure    Alternative splicing    Calcium-binding    Digestion    Hydrolase    Multigene family    Serine protease    Signal    Zymogen    EC: 3.4.21.4 SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Trypsin(ogen)    Human (Homo sapiens), trypsin IV (brain isoform) GO:  chymotrypsin activity    trypsin activity    proteolysis and peptidolysis

Image Source: PDB

Loops in ArchDB95 clusters

1h4w_A_155 - EH => SUBCLASS : 3.1.9
1h4w_A_155 - EH => SUBCLASS : 4.10.4
1h4w_A_51 - AR => SUBCLASS : 7.7.1
1h4w_A_20 - AR => SUBCLASS : 8.3.1
1h4w_A_40 - HA => SUBCLASS : 2.2.1
1h4w_A_81 - HA => SUBCLASS : 12.1.1
1h4w_A_64 - HA => SUBCLASS : 12.4.1

Loops in ArchDB-EC clusters

1h4w_A_64 - HA => SUBCLASS : 12.3.1

Loops not clustered in ArchDB

1h4w_A_51 - AR
1h4w_A_20 - AR
1h4w_A_104 - AR
1h4w_A_179 - AR
1h4w_A_104 - AR
1h4w_A_179 - AR
1h4w_A_225 - EH
1h4w_A_134 - HA
1h4w_A_81 - HA
1h4w_A_197 - HA
1h4w_A_64 - HA
1h4w_A_40 - HA
1h4w_A_30 - HA
1h4w_A_203 - HA
1h4w_A_197 - HA
1h4w_A_134 - HA
1h4w_A_30 - HA
1h4w_A_203 - HA
1h4w_A_164 - HE

1a0j B - percentage of sequence identity: 67
1a0j C - percentage of sequence identity: 67
1a0j D - percentage of sequence identity: 67
1aks A - percentage of sequence identity: 82
1aks B - percentage of sequence identity: 73
1amh A - percentage of sequence identity: 77
1amh B - percentage of sequence identity: 77
1an1 E - percentage of sequence identity: 78
1anb - - percentage of sequence identity: 77
1anc - - percentage of sequence identity: 77
1and - - percentage of sequence identity: 77
1ane - - percentage of sequence identity: 77
1aq7 - - percentage of sequence identity: 72
1auj - - percentage of sequence identity: 72
1avw A - percentage of sequence identity: 78
1avx A - percentage of sequence identity: 78
1az8 - - percentage of sequence identity: 72
1bit - - percentage of sequence identity: 63
1bju - - percentage of sequence identity: 72
1bjv - - percentage of sequence identity: 72
1bra - - percentage of sequence identity: 76
1brb E - percentage of sequence identity: 76
1brc E - percentage of sequence identity: 76
1btp - - percentage of sequence identity: 72
1btw A - percentage of sequence identity: 72
1btx A - percentage of sequence identity: 72
1bty - - percentage of sequence identity: 72
1btz A - percentage of sequence identity: 72
1bzx E - percentage of sequence identity: 63
1c1n A - percentage of sequence identity: 72
1c1o A - percentage of sequence identity: 72
1c1p A - percentage of sequence identity: 72
1c1q A - percentage of sequence identity: 72
1c1r A - percentage of sequence identity: 72
1c1s A - percentage of sequence identity: 72
1c1t A - percentage of sequence identity: 72
1c2d A - percentage of sequence identity: 72
1c2e A - percentage of sequence identity: 72
1c2f A - percentage of sequence identity: 72
1c2g A - percentage of sequence identity: 72
1c2h A - percentage of sequence identity: 72
1c2i A - percentage of sequence identity: 72
1c2j A - percentage of sequence identity: 72
1c2k A - percentage of sequence identity: 72
1c2l A - percentage of sequence identity: 72
1c2m A - percentage of sequence identity: 72
1c5p A - percentage of sequence identity: 72
1c5q A - percentage of sequence identity: 72
1c5r A - percentage of sequence identity: 72
1c5s A - percentage of sequence identity: 72
1c5t A - percentage of sequence identity: 72
1c5u A - percentage of sequence identity: 72
1c5v A - percentage of sequence identity: 72
1c9p A - percentage of sequence identity: 78
1c9t A - percentage of sequence identity: 72
1c9t B - percentage of sequence identity: 72
1c9t C - percentage of sequence identity: 72
1c9t D - percentage of sequence identity: 72
1c9t E - percentage of sequence identity: 72
1c9t F - percentage of sequence identity: 72
1ce5 A - percentage of sequence identity: 72
1co7 E - percentage of sequence identity: 77
1d6r A - percentage of sequence identity: 72
1dpo - - percentage of sequence identity: 77
1eb2 A - percentage of sequence identity: 72
1eja A - percentage of sequence identity: 78
1ejm A - percentage of sequence identity: 72
1ejm C - percentage of sequence identity: 72
1ejm E - percentage of sequence identity: 72
1ept A - percentage of sequence identity: 88
1ept B - percentage of sequence identity: 79
1ept C - percentage of sequence identity: 73
1ezs C - percentage of sequence identity: 76
1ezs D - percentage of sequence identity: 76
1ezu C - percentage of sequence identity: 76
1ezu D - percentage of sequence identity: 76
1ezx C - percentage of sequence identity: 72
1f0t A - percentage of sequence identity: 72
1f0u A - percentage of sequence identity: 72
1f2s E - percentage of sequence identity: 72
1f5r A - percentage of sequence identity: 77
1fmg A - percentage of sequence identity: 78
1fn6 A - percentage of sequence identity: 78
1fy8 E - percentage of sequence identity: 77
1g36 A - percentage of sequence identity: 72
1g3b A - percentage of sequence identity: 72
1g3c A - percentage of sequence identity: 72
1g3d A - percentage of sequence identity: 72
1g3e A - percentage of sequence identity: 72
1g9i E - percentage of sequence identity: 72
1gbt - - percentage of sequence identity: 72
1ghz A - percentage of sequence identity: 72
1gi0 A - percentage of sequence identity: 72
1gi1 A - percentage of sequence identity: 72
1gi2 A - percentage of sequence identity: 72
1gi3 A - percentage of sequence identity: 72
1gi4 A - percentage of sequence identity: 72
1gi5 A - percentage of sequence identity: 72
1gi6 A - percentage of sequence identity: 72
1gj6 A - percentage of sequence identity: 72
1h9h E - percentage of sequence identity: 75
1h9i E - percentage of sequence identity: 78
1j14 A - percentage of sequence identity: 77
1j15 A - percentage of sequence identity: 74
1j16 A - percentage of sequence identity: 74
1j17 T - percentage of sequence identity: 74
1j8a A - percentage of sequence identity: 72
1jir A - percentage of sequence identity: 72
1jrs A - percentage of sequence identity: 72
1jrt A - percentage of sequence identity: 72
1k1i A - percentage of sequence identity: 72
1k1j A - percentage of sequence identity: 72
1k1l A - percentage of sequence identity: 72
1k1m A - percentage of sequence identity: 72
1k1n A - percentage of sequence identity: 72
1k1o A - percentage of sequence identity: 72
1k1p A - percentage of sequence identity: 72
1k9o E - percentage of sequence identity: 77
1ldt T - percentage of sequence identity: 78
1lqe A - percentage of sequence identity: 72
1max - - percentage of sequence identity: 72
1may - - percentage of sequence identity: 72
1mbq A - percentage of sequence identity: 63
1mct A - percentage of sequence identity: 78
1mts - - percentage of sequence identity: 72
1mtu - - percentage of sequence identity: 72
1mtv - - percentage of sequence identity: 72
1mtw - - percentage of sequence identity: 72
1n6x A - percentage of sequence identity: 72
1n6y A - percentage of sequence identity: 72
1nc6 A - percentage of sequence identity: 72
1ntp - - percentage of sequence identity: 71
1o2h A - percentage of sequence identity: 72
1o2i A - percentage of sequence identity: 72
1o2j A - percentage of sequence identity: 72
1o2k A - percentage of sequence identity: 72
1o2l A - percentage of sequence identity: 72
1o2m A - percentage of sequence identity: 72
1o2n A - percentage of sequence identity: 72
1o2o A - percentage of sequence identity: 72
1o2p A - percentage of sequence identity: 72
1o2q A - percentage of sequence identity: 72
1o2r A - percentage of sequence identity: 72
1o2s A - percentage of sequence identity: 72
1o2t A - percentage of sequence identity: 72
1o2u A - percentage of sequence identity: 72
1o2v A - percentage of sequence identity: 72
1o2w A - percentage of sequence identity: 72
1o2x A - percentage of sequence identity: 72
1o2y A - percentage of sequence identity: 72
1o2z A - percentage of sequence identity: 72
1o30 A - percentage of sequence identity: 72
1o31 A - percentage of sequence identity: 72
1o32 A - percentage of sequence identity: 72
1o33 A - percentage of sequence identity: 72
1o34 A - percentage of sequence identity: 72
1o35 A - percentage of sequence identity: 72
1o36 A - percentage of sequence identity: 72
1o37 A - percentage of sequence identity: 72
1o38 A - percentage of sequence identity: 72
1o39 A - percentage of sequence identity: 72
1o3a A - percentage of sequence identity: 72
1o3b A - percentage of sequence identity: 72
1o3c A - percentage of sequence identity: 72
1o3d A - percentage of sequence identity: 72
1o3e A - percentage of sequence identity: 72
1o3f A - percentage of sequence identity: 72
1o3g A - percentage of sequence identity: 72
1o3h A - percentage of sequence identity: 72
1o3i A - percentage of sequence identity: 72
1o3j A - percentage of sequence identity: 72
1o3k A - percentage of sequence identity: 72
1o3l A - percentage of sequence identity: 72
1o3m A - percentage of sequence identity: 72
1o3n A - percentage of sequence identity: 72
1o3o A - percentage of sequence identity: 72
1oph B - percentage of sequence identity: 72
1ox1 A - percentage of sequence identity: 72
1oyq A - percentage of sequence identity: 72
1p2i A - percentage of sequence identity: 72
1p2j A - percentage of sequence identity: 72
1p2k A - percentage of sequence identity: 72
1ppc E - percentage of sequence identity: 72
1ppe E - percentage of sequence identity: 72
1pph E - percentage of sequence identity: 72
1qa0 A - percentage of sequence identity: 72
1qb1 A - percentage of sequence identity: 72
1qb6 A - percentage of sequence identity: 72
1qb9 A - percentage of sequence identity: 72
1qbn A - percentage of sequence identity: 72
1qbo A - percentage of sequence identity: 72
1qcp A - percentage of sequence identity: 72
1ql7 A - percentage of sequence identity: 72
1ql8 A - percentage of sequence identity: 72
1ql9 A - percentage of sequence identity: 77
1qqu A - percentage of sequence identity: 78
1rxp A - percentage of sequence identity: 72
1s0q A - percentage of sequence identity: 72
1s0r A - percentage of sequence identity: 72
1s5s A - percentage of sequence identity: 78
1s6f A - percentage of sequence identity: 78
1s6h A - percentage of sequence identity: 78
1s81 A - percentage of sequence identity: 78
1s82 A - percentage of sequence identity: 78
1s84 A - percentage of sequence identity: 78
1s85 A - percentage of sequence identity: 78
1sbw A - percentage of sequence identity: 72
1sfi A - percentage of sequence identity: 72
1slu B - percentage of sequence identity: 77
1slv B - percentage of sequence identity: 77
1slw B - percentage of sequence identity: 77
1slx B - percentage of sequence identity: 77
1smf E - percentage of sequence identity: 72
1tab E - percentage of sequence identity: 72
1taw A - percentage of sequence identity: 72
1tfx A - percentage of sequence identity: 78
1tfx B - percentage of sequence identity: 78
1tgb - - percentage of sequence identity: 72
1tgc - - percentage of sequence identity: 72
1tgn - - percentage of sequence identity: 72
1tgs Z - percentage of sequence identity: 72
1tgt - - percentage of sequence identity: 72
1tio A - percentage of sequence identity: 72
1tld - - percentage of sequence identity: 72
1tng - - percentage of sequence identity: 72
1tnh - - percentage of sequence identity: 72
1tni - - percentage of sequence identity: 72
1tnj - - percentage of sequence identity: 72
1tnk - - percentage of sequence identity: 72
1tnl - - percentage of sequence identity: 72
1tpa E - percentage of sequence identity: 72
1tpo - - percentage of sequence identity: 72
1tpp - - percentage of sequence identity: 72
1tps - - percentage of sequence identity: 72
1trm A - percentage of sequence identity: 77
1trm B - percentage of sequence identity: 77
1trn B - percentage of sequence identity: 87
1tx6 A - percentage of sequence identity: 78
1tx6 B - percentage of sequence identity: 78
1tx6 C - percentage of sequence identity: 78
1tx6 D - percentage of sequence identity: 78
1tx7 A - percentage of sequence identity: 72
1tx8 A - percentage of sequence identity: 72
1tyn - - percentage of sequence identity: 72
1uhb A - percentage of sequence identity: 82
1uhb B - percentage of sequence identity: 74
1utj A - percentage of sequence identity: 63
1utk A - percentage of sequence identity: 63
1utl M - percentage of sequence identity: 63
1utm A - percentage of sequence identity: 63
1utn A - percentage of sequence identity: 72
1uto A - percentage of sequence identity: 72
1utp A - percentage of sequence identity: 72
1utq A - percentage of sequence identity: 72
1v2j T - percentage of sequence identity: 71
1v2k T - percentage of sequence identity: 70
1v2l T - percentage of sequence identity: 70
1v2m T - percentage of sequence identity: 70
1v2n T - percentage of sequence identity: 70
1v2o T - percentage of sequence identity: 71
1v2p T - percentage of sequence identity: 71
1v2q T - percentage of sequence identity: 71
1v2r T - percentage of sequence identity: 71
1v2s T - percentage of sequence identity: 71
1v2t T - percentage of sequence identity: 71
1v2u T - percentage of sequence identity: 71
1v2v T - percentage of sequence identity: 71
1v2w T - percentage of sequence identity: 71
1v6d A - percentage of sequence identity: 78
1xuf - - percentage of sequence identity: 72
1xug - - percentage of sequence identity: 72
1xuh - - percentage of sequence identity: 72
1xui - - percentage of sequence identity: 72
1xuj - - percentage of sequence identity: 72
1xuk - - percentage of sequence identity: 72
1y3u A - percentage of sequence identity: 72
1y3v A - percentage of sequence identity: 72
1y3w A - percentage of sequence identity: 72
1y3x A - percentage of sequence identity: 72
1y3y A - percentage of sequence identity: 72
1y59 T - percentage of sequence identity: 72
1y5a T - percentage of sequence identity: 72
1y5b T - percentage of sequence identity: 72
1y5u T - percentage of sequence identity: 72
1yf4 A - percentage of sequence identity: 78
1yp9 A - percentage of sequence identity: 72
1yyy 1 - percentage of sequence identity: 72
1z7k A - percentage of sequence identity: 78
1zr0 A - percentage of sequence identity: 72
1zr0 C - percentage of sequence identity: 72
1zzz A - percentage of sequence identity: 72
2a7h A - percentage of sequence identity: 72
2ayw A - percentage of sequence identity: 72
2blv A - percentage of sequence identity: 72
2blw A - percentage of sequence identity: 72
2btc E - percentage of sequence identity: 72
2by5 X - percentage of sequence identity: 72
2by6 X - percentage of sequence identity: 72
2by7 X - percentage of sequence identity: 72
2by8 X - percentage of sequence identity: 72
2by9 X - percentage of sequence identity: 72
2bya X - percentage of sequence identity: 72
2bza A - percentage of sequence identity: 72
2fi3 E - percentage of sequence identity: 72
2fi4 E - percentage of sequence identity: 72
2fi5 E - percentage of sequence identity: 72
2ftl E - percentage of sequence identity: 72
2ftm A - percentage of sequence identity: 72
2fx4 A - percentage of sequence identity: 72
2fx6 A - percentage of sequence identity: 72
2ptc E - percentage of sequence identity: 72
2ptn - - percentage of sequence identity: 72
2sta E - percentage of sequence identity: 63
2stb E - percentage of sequence identity: 63
2tbs - - percentage of sequence identity: 63
2tga - - percentage of sequence identity: 72
2tgd - - percentage of sequence identity: 72
2tgp Z - percentage of sequence identity: 72
2tgt - - percentage of sequence identity: 72
2tio A - percentage of sequence identity: 72
2tld E - percentage of sequence identity: 72
2tpi Z - percentage of sequence identity: 72
2trm - - percentage of sequence identity: 77
3btd E - percentage of sequence identity: 72
3bte E - percentage of sequence identity: 72
3btf E - percentage of sequence identity: 72
3btg E - percentage of sequence identity: 72
3bth E - percentage of sequence identity: 72
3btk E - percentage of sequence identity: 72
3btm E - percentage of sequence identity: 72
3btq E - percentage of sequence identity: 72
3btt E - percentage of sequence identity: 72
3btw E - percentage of sequence identity: 72
3ptb - - percentage of sequence identity: 72
3ptn - - percentage of sequence identity: 72
3tgi E - percentage of sequence identity: 77
3tgj E - percentage of sequence identity: 77
3tgk E - percentage of sequence identity: 76
3tpi Z - percentage of sequence identity: 72
4tpi Z - percentage of sequence identity: 72
5ptp - - percentage of sequence identity: 72