PDB: 1trn Compound: Trypsin complexed with the inhibitor diisopropyl-f Classification: HYDROLASE (SERINE PROTEINASE) Entry date in PDB: 1995-06-03 Resolution [Å]: 2.20 R-Factor: 0.177

CHAIN: A SWISS-PROT/TREMBL: P07477    KEYWORD: 3D-structure    Calcium-binding    Digestion    Disease mutation    Hydrolase    Multigene family    Pancreas    Phosphorylation    Serine protease    Signal    Zymogen    EC: 3.4.21.4 SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Trypsin(ogen)    Human (Homo sapiens) GO:  chymotrypsin activity    trypsin activity    proteolysis and peptidolysis    CHAIN: B SWISS-PROT/TREMBL: P07477    KEYWORD: 3D-structure    Calcium-binding    Digestion    Disease mutation    Hydrolase    Multigene family    Pancreas    Phosphorylation    Serine protease    Signal    Zymogen    EC: 3.4.21.4 SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Trypsin(ogen)    Human (Homo sapiens) GO:  chymotrypsin activity    trypsin activity    proteolysis and peptidolysis

Image Source: PDB

Loops in ArchDB95 clusters

1trn_A_51 - AR => SUBCLASS : 7.7.1
1trn_A_20 - AR => SUBCLASS : 8.3.1
1trn_A_180 - AR => SUBCLASS : 16.1.1
1trn_A_104 - AR => SUBCLASS : 24.1.1
1trn_A_40 - HA => SUBCLASS : 2.2.1
1trn_A_81 - HA => SUBCLASS : 12.1.1
1trn_A_64 - HA => SUBCLASS : 12.4.1
1trn_A_135 - HA => SUBCLASS : 15.3.1

Loops in ArchDB-EC clusters

1trn_A_135 - HA => SUBCLASS : 15.2.1

Loops not clustered in ArchDB

1trn_A_51 - AR
1trn_A_20 - AR
1trn_A_104 - AR
1trn_A_180 - AR
1trn_A_226 - EH
1trn_A_156 - EH
1trn_A_135 - HA
1trn_A_198 - HA
1trn_A_81 - HA
1trn_A_64 - HA
1trn_A_40 - HA
1trn_A_30 - HA
1trn_A_204 - HA
1trn_A_198 - HA
1trn_A_30 - HA
1trn_A_204 - HA
1trn_A_165 - HE

1a0j A - percentage of sequence identity: 68
1a0j B - percentage of sequence identity: 68
1a0j C - percentage of sequence identity: 68
1a0j D - percentage of sequence identity: 68
1aks A - percentage of sequence identity: 78
1aks B - percentage of sequence identity: 79
1amh A - percentage of sequence identity: 79
1amh B - percentage of sequence identity: 79
1an1 E - percentage of sequence identity: 78
1anb - - percentage of sequence identity: 79
1anc - - percentage of sequence identity: 79
1and - - percentage of sequence identity: 79
1ane - - percentage of sequence identity: 80
1aq7 - - percentage of sequence identity: 75
1auj - - percentage of sequence identity: 75
1avw A - percentage of sequence identity: 78
1avx A - percentage of sequence identity: 78
1az8 - - percentage of sequence identity: 75
1bit - - percentage of sequence identity: 63
1bju - - percentage of sequence identity: 75
1bjv - - percentage of sequence identity: 75
1bra - - percentage of sequence identity: 79
1brb E - percentage of sequence identity: 79
1brc E - percentage of sequence identity: 79
1btp - - percentage of sequence identity: 75
1btw A - percentage of sequence identity: 75
1btx A - percentage of sequence identity: 75
1bty - - percentage of sequence identity: 75
1btz A - percentage of sequence identity: 75
1bzx E - percentage of sequence identity: 63
1c1n A - percentage of sequence identity: 75
1c1o A - percentage of sequence identity: 75
1c1p A - percentage of sequence identity: 75
1c1q A - percentage of sequence identity: 75
1c1r A - percentage of sequence identity: 75
1c1s A - percentage of sequence identity: 75
1c1t A - percentage of sequence identity: 75
1c2d A - percentage of sequence identity: 75
1c2e A - percentage of sequence identity: 75
1c2f A - percentage of sequence identity: 75
1c2g A - percentage of sequence identity: 75
1c2h A - percentage of sequence identity: 75
1c2i A - percentage of sequence identity: 75
1c2j A - percentage of sequence identity: 75
1c2k A - percentage of sequence identity: 75
1c2l A - percentage of sequence identity: 75
1c2m A - percentage of sequence identity: 75
1c5p A - percentage of sequence identity: 75
1c5q A - percentage of sequence identity: 75
1c5r A - percentage of sequence identity: 75
1c5s A - percentage of sequence identity: 75
1c5t A - percentage of sequence identity: 75
1c5u A - percentage of sequence identity: 75
1c5v A - percentage of sequence identity: 75
1c9p A - percentage of sequence identity: 78
1c9t A - percentage of sequence identity: 75
1c9t B - percentage of sequence identity: 75
1c9t C - percentage of sequence identity: 75
1c9t D - percentage of sequence identity: 75
1c9t E - percentage of sequence identity: 75
1c9t F - percentage of sequence identity: 75
1ce5 A - percentage of sequence identity: 75
1co7 E - percentage of sequence identity: 79
1d6r A - percentage of sequence identity: 75
1dpo - - percentage of sequence identity: 79
1eb2 A - percentage of sequence identity: 75
1eja A - percentage of sequence identity: 78
1ejm A - percentage of sequence identity: 75
1ejm C - percentage of sequence identity: 75
1ejm E - percentage of sequence identity: 75
1ept A - percentage of sequence identity: 83
1ept B - percentage of sequence identity: 75
1ept C - percentage of sequence identity: 79
1ezs C - percentage of sequence identity: 79
1ezs D - percentage of sequence identity: 79
1ezu C - percentage of sequence identity: 79
1ezu D - percentage of sequence identity: 79
1ezx C - percentage of sequence identity: 75
1f0t A - percentage of sequence identity: 75
1f0u A - percentage of sequence identity: 75
1f2s E - percentage of sequence identity: 75
1f5r A - percentage of sequence identity: 79
1f7z A - percentage of sequence identity: 80
1fmg A - percentage of sequence identity: 78
1fn6 A - percentage of sequence identity: 78
1fni A - percentage of sequence identity: 78
1fxy A - percentage of sequence identity: 69
1fy8 E - percentage of sequence identity: 80
1g36 A - percentage of sequence identity: 75
1g3b A - percentage of sequence identity: 75
1g3c A - percentage of sequence identity: 75
1g3d A - percentage of sequence identity: 75
1g3e A - percentage of sequence identity: 75
1g9i E - percentage of sequence identity: 75
1gbt - - percentage of sequence identity: 75
1ghz A - percentage of sequence identity: 75
1gi0 A - percentage of sequence identity: 75
1gi1 A - percentage of sequence identity: 75
1gi2 A - percentage of sequence identity: 75
1gi3 A - percentage of sequence identity: 75
1gi4 A - percentage of sequence identity: 75
1gi5 A - percentage of sequence identity: 75
1gi6 A - percentage of sequence identity: 75
1gj6 A - percentage of sequence identity: 75
1h4w A - percentage of sequence identity: 87
1h9h E - percentage of sequence identity: 76
1h9i E - percentage of sequence identity: 78
1hj8 A - percentage of sequence identity: 63
1hj9 A - percentage of sequence identity: 75
1j14 A - percentage of sequence identity: 79
1j15 A - percentage of sequence identity: 77
1j16 A - percentage of sequence identity: 77
1j17 T - percentage of sequence identity: 77
1j8a A - percentage of sequence identity: 75
1jir A - percentage of sequence identity: 75
1jrs A - percentage of sequence identity: 75
1jrt A - percentage of sequence identity: 75
1k1i A - percentage of sequence identity: 75
1k1j A - percentage of sequence identity: 75
1k1l A - percentage of sequence identity: 75
1k1m A - percentage of sequence identity: 75
1k1n A - percentage of sequence identity: 75
1k1o A - percentage of sequence identity: 75
1k1p A - percentage of sequence identity: 75
1k9o E - percentage of sequence identity: 79
1ldt T - percentage of sequence identity: 78
1lqe A - percentage of sequence identity: 75
1max - - percentage of sequence identity: 75
1may - - percentage of sequence identity: 75
1mbq A - percentage of sequence identity: 63
1mct A - percentage of sequence identity: 78
1mts - - percentage of sequence identity: 75
1mtu - - percentage of sequence identity: 75
1mtv - - percentage of sequence identity: 75
1mtw - - percentage of sequence identity: 75
1n6x A - percentage of sequence identity: 75
1n6y A - percentage of sequence identity: 75
1nc6 A - percentage of sequence identity: 75
1ntp - - percentage of sequence identity: 74
1o2h A - percentage of sequence identity: 75
1o2i A - percentage of sequence identity: 75
1o2j A - percentage of sequence identity: 75
1o2k A - percentage of sequence identity: 75
1o2l A - percentage of sequence identity: 75
1o2m A - percentage of sequence identity: 75
1o2n A - percentage of sequence identity: 75
1o2o A - percentage of sequence identity: 75
1o2p A - percentage of sequence identity: 75
1o2q A - percentage of sequence identity: 75
1o2r A - percentage of sequence identity: 75
1o2s A - percentage of sequence identity: 75
1o2t A - percentage of sequence identity: 75
1o2u A - percentage of sequence identity: 75
1o2v A - percentage of sequence identity: 75
1o2w A - percentage of sequence identity: 75
1o2x A - percentage of sequence identity: 75
1o2y A - percentage of sequence identity: 75
1o2z A - percentage of sequence identity: 75
1o30 A - percentage of sequence identity: 75
1o31 A - percentage of sequence identity: 75
1o32 A - percentage of sequence identity: 75
1o33 A - percentage of sequence identity: 75
1o34 A - percentage of sequence identity: 75
1o35 A - percentage of sequence identity: 75
1o36 A - percentage of sequence identity: 75
1o37 A - percentage of sequence identity: 75
1o38 A - percentage of sequence identity: 75
1o39 A - percentage of sequence identity: 75
1o3a A - percentage of sequence identity: 75
1o3b A - percentage of sequence identity: 75
1o3c A - percentage of sequence identity: 75
1o3d A - percentage of sequence identity: 75
1o3e A - percentage of sequence identity: 75
1o3f A - percentage of sequence identity: 75
1o3g A - percentage of sequence identity: 75
1o3h A - percentage of sequence identity: 75
1o3i A - percentage of sequence identity: 75
1o3j A - percentage of sequence identity: 75
1o3k A - percentage of sequence identity: 75
1o3l A - percentage of sequence identity: 75
1o3m A - percentage of sequence identity: 75
1o3n A - percentage of sequence identity: 75
1o3o A - percentage of sequence identity: 75
1oph B - percentage of sequence identity: 74
1ox1 A - percentage of sequence identity: 75
1oyq A - percentage of sequence identity: 75
1p2i A - percentage of sequence identity: 75
1p2j A - percentage of sequence identity: 75
1p2k A - percentage of sequence identity: 75
1ppc E - percentage of sequence identity: 75
1ppe E - percentage of sequence identity: 75
1pph E - percentage of sequence identity: 75
1qa0 A - percentage of sequence identity: 75
1qb1 A - percentage of sequence identity: 75
1qb6 A - percentage of sequence identity: 75
1qb9 A - percentage of sequence identity: 75
1qbn A - percentage of sequence identity: 75
1qbo A - percentage of sequence identity: 75
1qcp A - percentage of sequence identity: 75
1ql7 A - percentage of sequence identity: 75
1ql8 A - percentage of sequence identity: 75
1ql9 A - percentage of sequence identity: 79
1qqu A - percentage of sequence identity: 78
1rxp A - percentage of sequence identity: 75
1s0q A - percentage of sequence identity: 75
1s0r A - percentage of sequence identity: 75
1s5s A - percentage of sequence identity: 78
1s6f A - percentage of sequence identity: 78
1s6h A - percentage of sequence identity: 78
1s81 A - percentage of sequence identity: 78
1s82 A - percentage of sequence identity: 78
1s83 A - percentage of sequence identity: 78
1s84 A - percentage of sequence identity: 78
1s85 A - percentage of sequence identity: 78
1sbw A - percentage of sequence identity: 75
1sfi A - percentage of sequence identity: 75
1slu B - percentage of sequence identity: 79
1slv B - percentage of sequence identity: 79
1slw B - percentage of sequence identity: 80
1slx B - percentage of sequence identity: 79
1smf E - percentage of sequence identity: 75
1tab E - percentage of sequence identity: 75
1taw A - percentage of sequence identity: 75
1tfx A - percentage of sequence identity: 78
1tfx B - percentage of sequence identity: 78
1tgb - - percentage of sequence identity: 75
1tgc - - percentage of sequence identity: 75
1tgn - - percentage of sequence identity: 75
1tgs Z - percentage of sequence identity: 75
1tgt - - percentage of sequence identity: 75
1tio A - percentage of sequence identity: 75
1tld - - percentage of sequence identity: 75
1tng - - percentage of sequence identity: 75
1tnh - - percentage of sequence identity: 75
1tni - - percentage of sequence identity: 75
1tnj - - percentage of sequence identity: 75
1tnk - - percentage of sequence identity: 75
1tnl - - percentage of sequence identity: 75
1tpa E - percentage of sequence identity: 75
1tpo - - percentage of sequence identity: 75
1tpp - - percentage of sequence identity: 75
1tps - - percentage of sequence identity: 75
1trm A - percentage of sequence identity: 79
1trm B - percentage of sequence identity: 79
1trn A - percentage of sequence identity: 100
1trn B - percentage of sequence identity: 100
1tx6 A - percentage of sequence identity: 78
1tx6 B - percentage of sequence identity: 78
1tx6 C - percentage of sequence identity: 78
1tx6 D - percentage of sequence identity: 78
1tx7 A - percentage of sequence identity: 75
1tx8 A - percentage of sequence identity: 75
1tyn - - percentage of sequence identity: 75
1uhb A - percentage of sequence identity: 78
1uhb B - percentage of sequence identity: 80
1utj A - percentage of sequence identity: 63
1utk A - percentage of sequence identity: 63
1utl M - percentage of sequence identity: 63
1utm A - percentage of sequence identity: 63
1utn A - percentage of sequence identity: 75
1uto A - percentage of sequence identity: 75
1utp A - percentage of sequence identity: 75
1utq A - percentage of sequence identity: 75
1v2j T - percentage of sequence identity: 73
1v2k T - percentage of sequence identity: 73
1v2l T - percentage of sequence identity: 73
1v2m T - percentage of sequence identity: 73
1v2n T - percentage of sequence identity: 73
1v2o T - percentage of sequence identity: 73
1v2p T - percentage of sequence identity: 73
1v2q T - percentage of sequence identity: 73
1v2r T - percentage of sequence identity: 73
1v2s T - percentage of sequence identity: 73
1v2t T - percentage of sequence identity: 73
1v2u T - percentage of sequence identity: 73
1v2v T - percentage of sequence identity: 73
1v2w T - percentage of sequence identity: 73
1v6d A - percentage of sequence identity: 78
1xuf - - percentage of sequence identity: 75
1xug - - percentage of sequence identity: 75
1xuh - - percentage of sequence identity: 75
1xui - - percentage of sequence identity: 75
1xuj - - percentage of sequence identity: 75
1xuk - - percentage of sequence identity: 75
1y3u A - percentage of sequence identity: 75
1y3v A - percentage of sequence identity: 75
1y3w A - percentage of sequence identity: 75
1y3x A - percentage of sequence identity: 75
1y3y A - percentage of sequence identity: 75
1y59 T - percentage of sequence identity: 74
1y5a T - percentage of sequence identity: 74
1y5b T - percentage of sequence identity: 74
1y5u T - percentage of sequence identity: 74
1yf4 A - percentage of sequence identity: 78
1yp9 A - percentage of sequence identity: 75
1yyy 1 - percentage of sequence identity: 75
1z7k A - percentage of sequence identity: 78
1zr0 A - percentage of sequence identity: 75
1zr0 C - percentage of sequence identity: 75
1zzz A - percentage of sequence identity: 75
2a7h A - percentage of sequence identity: 75
2ayw A - percentage of sequence identity: 75
2blv A - percentage of sequence identity: 75
2blw A - percentage of sequence identity: 75
2btc E - percentage of sequence identity: 75
2by5 X - percentage of sequence identity: 75
2by6 X - percentage of sequence identity: 75
2by7 X - percentage of sequence identity: 75
2by8 X - percentage of sequence identity: 75
2by9 X - percentage of sequence identity: 75
2bya X - percentage of sequence identity: 75
2bza A - percentage of sequence identity: 75
2fi3 E - percentage of sequence identity: 75
2fi4 E - percentage of sequence identity: 74
2fi5 E - percentage of sequence identity: 74
2ftl E - percentage of sequence identity: 74
2ftm A - percentage of sequence identity: 74
2fx4 A - percentage of sequence identity: 75
2fx6 A - percentage of sequence identity: 75
2ptc E - percentage of sequence identity: 75
2ptn - - percentage of sequence identity: 75
2sta E - percentage of sequence identity: 63
2stb E - percentage of sequence identity: 63
2tbs - - percentage of sequence identity: 63
2tga - - percentage of sequence identity: 75
2tgd - - percentage of sequence identity: 75
2tgp Z - percentage of sequence identity: 75
2tgt - - percentage of sequence identity: 75
2tio A - percentage of sequence identity: 75
2tld E - percentage of sequence identity: 74
2tpi Z - percentage of sequence identity: 75
2trm - - percentage of sequence identity: 79
3btd E - percentage of sequence identity: 75
3bte E - percentage of sequence identity: 75
3btf E - percentage of sequence identity: 75
3btg E - percentage of sequence identity: 75
3bth E - percentage of sequence identity: 75
3btk E - percentage of sequence identity: 75
3btm E - percentage of sequence identity: 75
3btq E - percentage of sequence identity: 75
3btt E - percentage of sequence identity: 75
3btw E - percentage of sequence identity: 75
3ptb - - percentage of sequence identity: 75
3ptn - - percentage of sequence identity: 75
3tgi E - percentage of sequence identity: 80
3tgj E - percentage of sequence identity: 79
3tgk E - percentage of sequence identity: 79
3tpi Z - percentage of sequence identity: 75
4tpi Z - percentage of sequence identity: 75
5ptp - - percentage of sequence identity: 75