PDB: 1hav Compound: hepatitis a virus 3c proteinase Classification: HYDROLASE Entry date in PDB: 1996-12-23 Resolution [Å]: 2.00 R-Factor: 0.211

CHAIN: A SWISS-PROT/TREMBL: P08617    KEYWORD: 3D-structure    Coat protein    Core protein    Hydrolase    Polyprotein    RNA-directed RNA polymerase    Thiol protease    Transferase    EC: 2.7.7.48 SCOP: b.47.1.4 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Viral cysteine protease of trypsin fold    3C cysteine protease (picornain 3C)    Human hepatitis A virus GO:  viral capsid    ATP binding    helicase activity    RNA binding    RNA helicase activity    RNA-directed RNA polymerase activity    structural molecule activity    transcription    viral genome replication    CHAIN: B SWISS-PROT/TREMBL: P08617    KEYWORD: 3D-structure    Coat protein    Core protein    Hydrolase    Polyprotein    RNA-directed RNA polymerase    Thiol protease    Transferase    EC: 2.7.7.48 SCOP: b.47.1.4 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Viral cysteine protease of trypsin fold    3C cysteine protease (picornain 3C)    Human hepatitis A virus GO:  viral capsid    ATP binding    helicase activity    RNA binding    RNA helicase activity    RNA-directed RNA polymerase activity    structural molecule activity    transcription    viral genome replication

Image Source: PDB

Loops in ArchDB40 clusters

1hav_A_56 - HA => SUBCLASS : 2.1.1
1hav_A_25 - HA => SUBCLASS : 2.3.21
1hav_A_65 - AR => SUBCLASS : 4.2.1

Loops in ArchDB95 clusters

1hav_A_65 - AR => SUBCLASS : 3.2.3
1hav_A_65 - AR => SUBCLASS : 4.4.1
1hav_A_38 - AR => SUBCLASS : 12.6.1
1hav_A_56 - HA => SUBCLASS : 2.1.1

Loops not clustered in ArchDB

1hav_A_85 - AR
1hav_A_126 - AR
1hav_A_152 - AR
1hav_A_12 - HA
1hav_A_187 - HA
1hav_A_175 - HA
1hav_A_136 - HA
1hav_A_117 - HA
1hav_A_74 - HA
1hav_A_2 - HE

1hav A - percentage of sequence identity: 100
1hav B - percentage of sequence identity: 100
1qa7 A - percentage of sequence identity: 99
1qa7 B - percentage of sequence identity: 99
1qa7 C - percentage of sequence identity: 99
1qa7 D - percentage of sequence identity: 99
2a4o A - percentage of sequence identity: 100
2cxv A - percentage of sequence identity: 100