PDB: 1huc Compound: Cathepsin b Classification: THIOL PROTEASE Entry date in PDB: 1995-01-26 Resolution [Å]: 2.10 R-Factor: 0.164

CHAIN: A SWISS-PROT/TREMBL: P07858    KEYWORD: 3D-structure    Glycoprotein    Hydrolase    Lysosome    Polymorphism    Signal    Thiol protease    Zymogen    EC: 3.4.22.1 SCOP: d.3.1.1 Alpha and beta proteins (a+b)    Cysteine proteinases    Cysteine proteinases    Papain-like    (Pro)cathepsin B    Human (Homo sapiens) GO:  cysteine-type endopeptidase activity    cysteine-type peptidase activity    proteolysis and peptidolysis    CHAIN: B SWISS-PROT/TREMBL: P07858    KEYWORD: 3D-structure    Glycoprotein    Hydrolase    Lysosome    Polymorphism    Signal    Thiol protease    Zymogen    EC: 3.4.22.1 SCOP: d.3.1.1 Alpha and beta proteins (a+b)    Cysteine proteinases    Cysteine proteinases    Papain-like    (Pro)cathepsin B    Human (Homo sapiens) GO:  cysteine-type endopeptidase activity    cysteine-type peptidase activity    proteolysis and peptidolysis    CHAIN: C SWISS-PROT/TREMBL: P07858    KEYWORD: 3D-structure    Glycoprotein    Hydrolase    Lysosome    Polymorphism    Signal    Thiol protease    Zymogen    EC: 3.4.22.1 SCOP: d.3.1.1 Alpha and beta proteins (a+b)    Cysteine proteinases    Cysteine proteinases    Papain-like    (Pro)cathepsin B    Human (Homo sapiens) GO:  cysteine-type endopeptidase activity    cysteine-type peptidase activity    proteolysis and peptidolysis    CHAIN: D SWISS-PROT/TREMBL: P07858    KEYWORD: 3D-structure    Glycoprotein    Hydrolase    Lysosome    Polymorphism    Signal    Thiol protease    Zymogen    EC: 3.4.22.1 SCOP: d.3.1.1 Alpha and beta proteins (a+b)    Cysteine proteinases    Cysteine proteinases    Papain-like    (Pro)cathepsin B    Human (Homo sapiens) GO:  cysteine-type endopeptidase activity    cysteine-type peptidase activity    proteolysis and peptidolysis

Image Source: PDB

Loops in ArchDB95 clusters

1huc_B_151 - EH => SUBCLASS : 4.15.2
1huc_B_230 - AR => SUBCLASS : 11.7.1
1huc_B_56 - HH => SUBCLASS : 12.9.1
1huc_A_7 - HH => SUBCLASS : 16.6.1
1huc_B_212 - HA => SUBCLASS : 11.1.1

Loops not clustered in ArchDB

1huc_B_170 - HA
1huc_B_195 - HA
1huc_B_76 - HE
1huc_B_157 - HE

1cpj A - percentage of sequence identity: 83
1cpj B - percentage of sequence identity: 83
1csb B - percentage of sequence identity: 100
1csb E - percentage of sequence identity: 100
1cte A - percentage of sequence identity: 83
1cte B - percentage of sequence identity: 83
1gmy A - percentage of sequence identity: 100
1gmy B - percentage of sequence identity: 100
1gmy C - percentage of sequence identity: 100
1huc B - percentage of sequence identity: 100
1huc D - percentage of sequence identity: 100
1ito A - percentage of sequence identity: 88
1mir A - percentage of sequence identity: 83
1mir B - percentage of sequence identity: 83
1pbh - - percentage of sequence identity: 100
1qdq A - percentage of sequence identity: 93
1sp4 B - percentage of sequence identity: 87
1the A - percentage of sequence identity: 87
1the B - percentage of sequence identity: 83
2dc6 A - percentage of sequence identity: 88
2dc7 A - percentage of sequence identity: 88
2dc8 A - percentage of sequence identity: 88
2dc9 A - percentage of sequence identity: 88
2dca A - percentage of sequence identity: 88
2dcb A - percentage of sequence identity: 88
2dcc A - percentage of sequence identity: 88
2dcd A - percentage of sequence identity: 88
2pbh - - percentage of sequence identity: 100
3pbh - - percentage of sequence identity: 100