PDB: 1j7n Compound: lethal factor precursor Classification: TOXIN Entry date in PDB: 2001-11-07 Resolution [Å]: 2.30 R-Factor: 0.229

CHAIN: A SWISS-PROT/TREMBL: P15917    KEYWORD: 3D-structure    Hydrolase    Metal-binding    Metalloprotease    Plasmid    Repeat    Signal    Toxin    Virulence    Zinc    EC: 3.4.24.83 SCOP: d.92.1.14 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Anthrax toxin lethal factor, N- and C-terminal domains    Anthrax toxin lethal factor, N- and C-terminal domains    Bacillus anthracis SCOP: d.92.1.14 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Anthrax toxin lethal factor, N- and C-terminal domains    Anthrax toxin lethal factor, N- and C-terminal domains    Bacillus anthracis SCOP: d.166.1.1 Alpha and beta proteins (a+b)    ADP-ribosylation    ADP-ribosylation    ADP-ribosylating toxins    Anthrax toxin lethal factor, middle domain    Bacillus anthracis GO:  extracellular region    metallopeptidase activity    zinc ion binding    pathogenesis    proteolysis and peptidolysis    CHAIN: B SWISS-PROT/TREMBL: P15917    KEYWORD: 3D-structure    Hydrolase    Metal-binding    Metalloprotease    Plasmid    Repeat    Signal    Toxin    Virulence    Zinc    EC: 3.4.24.83 SCOP: d.92.1.14 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Anthrax toxin lethal factor, N- and C-terminal domains    Anthrax toxin lethal factor, N- and C-terminal domains    Bacillus anthracis SCOP: d.92.1.14 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Anthrax toxin lethal factor, N- and C-terminal domains    Anthrax toxin lethal factor, N- and C-terminal domains    Bacillus anthracis SCOP: d.166.1.1 Alpha and beta proteins (a+b)    ADP-ribosylation    ADP-ribosylation    ADP-ribosylating toxins    Anthrax toxin lethal factor, middle domain    Bacillus anthracis GO:  extracellular region    metallopeptidase activity    zinc ion binding    pathogenesis    proteolysis and peptidolysis

Image Source: PDB

Loops in ArchDB40 clusters

1j7n_A_33 - HE => SUBCLASS : 0.1.3
1j7n_A_68 - HE => SUBCLASS : 2.1.2
1j7n_A_68 - HE => SUBCLASS : 2.2.3
1j7n_A_612 - HE => SUBCLASS : 3.2.4
1j7n_A_525 - HA => SUBCLASS : 2.1.5
1j7n_A_103 - HA => SUBCLASS : 3.1.1
1j7n_A_511 - HA => SUBCLASS : 3.1.1
1j7n_A_657 - HA => SUBCLASS : 4.1.1
1j7n_A_119 - HA => SUBCLASS : 5.17.1
1j7n_A_128 - EH => SUBCLASS : 6.3.3
1j7n_A_518 - AR => SUBCLASS : 3.5.3
1j7n_A_499 - AR => SUBCLASS : 5.5.1
1j7n_A_111 - AR => SUBCLASS : 5.12.1
1j7n_A_210 - HH => SUBCLASS : 1.1.3
1j7n_A_251 - HH => SUBCLASS : 1.1.4
1j7n_A_210 - HH => SUBCLASS : 1.1.21
1j7n_A_749 - HH => SUBCLASS : 1.2.1
1j7n_A_210 - HH => SUBCLASS : 1.2.12
1j7n_A_54 - HH => SUBCLASS : 2.1.2
1j7n_A_592 - HH => SUBCLASS : 2.1.3
1j7n_A_54 - HH => SUBCLASS : 2.1.3
1j7n_A_279 - HH => SUBCLASS : 2.1.4
1j7n_A_184 - HH => SUBCLASS : 2.3.1
1j7n_A_168 - HH => SUBCLASS : 3.4.3
1j7n_A_733 - HH => SUBCLASS : 3.4.3
1j7n_A_373 - HH => SUBCLASS : 4.8.2

Loops in ArchDB95 clusters

1j7n_A_128 - EH => SUBCLASS : 6.3.1
1j7n_A_477 - AR => SUBCLASS : 3.1.21
1j7n_A_518 - AR => SUBCLASS : 3.6.12
1j7n_A_499 - AR => SUBCLASS : 4.6.1
1j7n_A_477 - AR => SUBCLASS : 4.15.3
1j7n_A_111 - AR => SUBCLASS : 5.5.2
1j7n_A_485 - AR => SUBCLASS : 11.11.1
1j7n_A_210 - HH => SUBCLASS : 1.1.4
1j7n_A_251 - HH => SUBCLASS : 1.1.4
1j7n_A_210 - HH => SUBCLASS : 1.1.8
1j7n_A_749 - HH => SUBCLASS : 1.2.1
1j7n_A_749 - HH => SUBCLASS : 1.2.6
1j7n_A_592 - HH => SUBCLASS : 2.1.1
1j7n_A_54 - HH => SUBCLASS : 2.1.1
1j7n_A_279 - HH => SUBCLASS : 2.1.1
1j7n_A_54 - HH => SUBCLASS : 2.1.2
1j7n_A_592 - HH => SUBCLASS : 2.3.1
1j7n_A_184 - HH => SUBCLASS : 2.3.3
1j7n_A_168 - HH => SUBCLASS : 3.3.1
1j7n_A_733 - HH => SUBCLASS : 3.3.1
1j7n_A_373 - HH => SUBCLASS : 4.6.1
1j7n_A_33 - HE => SUBCLASS : 0.1.2
1j7n_A_612 - HE => SUBCLASS : 2.1.8
1j7n_A_465 - HE => SUBCLASS : 2.3.23
1j7n_A_68 - HE => SUBCLASS : 2.5.1
1j7n_A_525 - HA => SUBCLASS : 2.1.3
1j7n_A_119 - HA => SUBCLASS : 2.3.13
1j7n_A_103 - HA => SUBCLASS : 3.1.1
1j7n_A_511 - HA => SUBCLASS : 3.1.1
1j7n_A_657 - HA => SUBCLASS : 4.1.1

Loops in ArchDB-EC clusters

1j7n_A_373 - HH => SUBCLASS : 4.11.2

Loops not clustered in ArchDB

1j7n_A_80 - AR
1j7n_A_629 - AR
1j7n_A_80 - AR
1j7n_A_111 - AR
1j7n_A_477 - AR
1j7n_A_485 - AR
1j7n_A_499 - AR
1j7n_A_518 - AR
1j7n_A_629 - AR
1j7n_A_43 - EH
1j7n_A_436 - EH
1j7n_A_540 - EH
1j7n_A_583 - EH
1j7n_A_665 - EH
1j7n_A_119 - HA
1j7n_A_103 - HA
1j7n_A_525 - HA
1j7n_A_511 - HA
1j7n_A_657 - HA
1j7n_A_406 - HE
1j7n_A_552 - HE
1j7n_A_448 - HH
1j7n_A_141 - HH
1j7n_A_192 - HH
1j7n_A_203 - HH
1j7n_A_227 - HH
1j7n_A_238 - HH
1j7n_A_264 - HH
1j7n_A_287 - HH
1j7n_A_304 - HH
1j7n_A_314 - HH
1j7n_A_332 - HH
1j7n_A_712 - HH
1j7n_A_680 - HH
1j7n_A_388 - HH

1j7n A - percentage of sequence identity: 100
1j7n B - percentage of sequence identity: 100
1jky A - percentage of sequence identity: 100
1pwp A - percentage of sequence identity: 100
1pwp B - percentage of sequence identity: 100
1pwq A - percentage of sequence identity: 100
1pwq B - percentage of sequence identity: 100
1pwu A - percentage of sequence identity: 99
1pwu B - percentage of sequence identity: 99
1pwv A - percentage of sequence identity: 100
1pwv B - percentage of sequence identity: 100
1pww A - percentage of sequence identity: 99
1pww B - percentage of sequence identity: 99
1yqy A - percentage of sequence identity: 99
1zxv A - percentage of sequence identity: 100
1zxv B - percentage of sequence identity: 100