PDB: 1n4p Compound: protein farnesyltransferase alpha subunit Classification: TRANSFERASE Entry date in PDB: 2003-11-18 Resolution [Å]: 2.65 R-Factor: 0.204

CHAIN: A SWISS-PROT/TREMBL: Q04631    KEYWORD: 3D-structure    Prenyltransferase    Repeat    Transferase    EC: 2.5.1.58 SCOP: a.118.6.1 All alpha proteins    alpha-alpha superhelix    Protein prenylyltransferase    Protein prenylyltransferase    Protein farnesyltransferase alpha-subunit    Rat (Rattus norvegicus) GO:  protein prenyltransferase activity    protein amino acid prenylation    CHAIN: B SWISS-PROT/TREMBL: P53610    KEYWORD: Prenyltransferase    Repeat    Transferase    Zinc    EC: 2.5.1.59 SCOP: a.102.4.3 All alpha proteins    alpha/alpha toroid    Terpenoid cyclases/Protein prenyltransferases    Protein prenyltransferases    Protein farnesyltransferase, beta-subunit    Rat (Rattus norvegicus) GO:  catalytic activity    CHAIN: C SWISS-PROT/TREMBL: Q04631    KEYWORD: 3D-structure    Prenyltransferase    Repeat    Transferase    EC: 2.5.1.58 SCOP: a.118.6.1 All alpha proteins    alpha-alpha superhelix    Protein prenylyltransferase    Protein prenylyltransferase    Protein farnesyltransferase alpha-subunit    Rat (Rattus norvegicus) GO:  protein prenyltransferase activity    protein amino acid prenylation    CHAIN: D SWISS-PROT/TREMBL: P53610    KEYWORD: Prenyltransferase    Repeat    Transferase    Zinc    EC: 2.5.1.59 SCOP: a.102.4.3 All alpha proteins    alpha/alpha toroid    Terpenoid cyclases/Protein prenyltransferases    Protein prenyltransferases    Protein farnesyltransferase, beta-subunit    Rat (Rattus norvegicus) GO:  catalytic activity    CHAIN: E SWISS-PROT/TREMBL: Q04631    KEYWORD: 3D-structure    Prenyltransferase    Repeat    Transferase    EC: 2.5.1.58 SCOP: a.118.6.1 All alpha proteins    alpha-alpha superhelix    Protein prenylyltransferase    Protein prenylyltransferase    Protein farnesyltransferase alpha-subunit    Rat (Rattus norvegicus) GO:  protein prenyltransferase activity    protein amino acid prenylation    CHAIN: F SWISS-PROT/TREMBL: P53610    KEYWORD: Prenyltransferase    Repeat    Transferase    Zinc    EC: 2.5.1.59 SCOP: a.102.4.3 All alpha proteins    alpha/alpha toroid    Terpenoid cyclases/Protein prenyltransferases    Protein prenyltransferases    Protein farnesyltransferase, beta-subunit    Rat (Rattus norvegicus) GO:  catalytic activity    CHAIN: G SWISS-PROT/TREMBL: Q04631    KEYWORD: 3D-structure    Prenyltransferase    Repeat    Transferase    EC: 2.5.1.58 SCOP: a.118.6.1 All alpha proteins    alpha-alpha superhelix    Protein prenylyltransferase    Protein prenylyltransferase    Protein farnesyltransferase alpha-subunit    Rat (Rattus norvegicus) GO:  protein prenyltransferase activity    protein amino acid prenylation    CHAIN: H SWISS-PROT/TREMBL: P53610    KEYWORD: Prenyltransferase    Repeat    Transferase    Zinc    EC: 2.5.1.59 SCOP: a.102.4.3 All alpha proteins    alpha/alpha toroid    Terpenoid cyclases/Protein prenyltransferases    Protein prenyltransferases    Protein farnesyltransferase, beta-subunit    Rat (Rattus norvegicus) GO:  catalytic activity    CHAIN: I SWISS-PROT/TREMBL: Q04631    KEYWORD: 3D-structure    Prenyltransferase    Repeat    Transferase    EC: 2.5.1.58 SCOP: a.118.6.1 All alpha proteins    alpha-alpha superhelix    Protein prenylyltransferase    Protein prenylyltransferase    Protein farnesyltransferase alpha-subunit    Rat (Rattus norvegicus) GO:  protein prenyltransferase activity    protein amino acid prenylation    CHAIN: J SWISS-PROT/TREMBL: P53610    KEYWORD: Prenyltransferase    Repeat    Transferase    Zinc    EC: 2.5.1.59 SCOP: a.102.4.3 All alpha proteins    alpha/alpha toroid    Terpenoid cyclases/Protein prenyltransferases    Protein prenyltransferases    Protein farnesyltransferase, beta-subunit    Rat (Rattus norvegicus) GO:  catalytic activity    CHAIN: K SWISS-PROT/TREMBL: Q04631    KEYWORD: 3D-structure    Prenyltransferase    Repeat    Transferase    EC: 2.5.1.58 SCOP: a.118.6.1 All alpha proteins    alpha-alpha superhelix    Protein prenylyltransferase    Protein prenylyltransferase    Protein farnesyltransferase alpha-subunit    Rat (Rattus norvegicus) GO:  protein prenyltransferase activity    protein amino acid prenylation    CHAIN: L SWISS-PROT/TREMBL: P53610    KEYWORD: Prenyltransferase    Repeat    Transferase    Zinc    EC: 2.5.1.59 SCOP: a.102.4.3 All alpha proteins    alpha/alpha toroid    Terpenoid cyclases/Protein prenyltransferases    Protein prenyltransferases    Protein farnesyltransferase, beta-subunit    Rat (Rattus norvegicus) GO:  catalytic activity    CHAIN: M SWISS-PROT/TREMBL: P61227    KEYWORD: GTP-binding    Lipoprotein    Prenylation    GO:   CHAIN: N SWISS-PROT/TREMBL: P61227    KEYWORD: GTP-binding    Lipoprotein    Prenylation    GO:

Image Source: PDB

Loops in ArchDB-EC clusters

1n4p_B_193 - HH => SUBCLASS : 16.2.1

Loops not clustered in ArchDB

1n4p_B_94 - EH
1n4p_B_170 - EH
1n4p_B_346 - EH
1n4p_B_161 - HA
1n4p_B_80 - HA
1n4p_B_340 - HA
1n4p_B_69 - HE
1n4p_B_144 - HE
1n4p_B_319 - HE
1n4p_B_22 - HH
1n4p_B_291 - HH
1n4p_B_272 - HH
1n4p_B_242 - HH
1n4p_B_236 - HH
1n4p_B_220 - HH
1n4p_B_122 - HH
1n4p_B_47 - HH
1n4p_B_172 - HH

1d8d A - percentage of sequence identity: 100
1n4p B - percentage of sequence identity: 100
1n4p D - percentage of sequence identity: 100
1n4p F - percentage of sequence identity: 100
1n4p H - percentage of sequence identity: 100
1n4p J - percentage of sequence identity: 100
1n4p L - percentage of sequence identity: 100
1n4q B - percentage of sequence identity: 100
1n4q D - percentage of sequence identity: 100
1n4q F - percentage of sequence identity: 100
1n4q H - percentage of sequence identity: 100
1n4q J - percentage of sequence identity: 100
1n4q L - percentage of sequence identity: 100
1n4r B - percentage of sequence identity: 100
1n4r D - percentage of sequence identity: 100
1n4r F - percentage of sequence identity: 100
1n4r H - percentage of sequence identity: 100
1n4r J - percentage of sequence identity: 100
1n4r L - percentage of sequence identity: 100
1n4s B - percentage of sequence identity: 100
1n4s D - percentage of sequence identity: 100
1n4s F - percentage of sequence identity: 100
1n4s H - percentage of sequence identity: 100
1n4s J - percentage of sequence identity: 100
1n4s L - percentage of sequence identity: 100
1s64 B - percentage of sequence identity: 100
1s64 D - percentage of sequence identity: 100
1s64 F - percentage of sequence identity: 100
1s64 H - percentage of sequence identity: 100
1s64 J - percentage of sequence identity: 100
1s64 L - percentage of sequence identity: 100
1tnb B - percentage of sequence identity: 100
1tnb D - percentage of sequence identity: 100
1tnb F - percentage of sequence identity: 100
1tnb H - percentage of sequence identity: 100
1tnb J - percentage of sequence identity: 100
1tnb L - percentage of sequence identity: 100
1tno B - percentage of sequence identity: 100
1tno D - percentage of sequence identity: 100
1tno F - percentage of sequence identity: 100
1tno H - percentage of sequence identity: 100
1tno J - percentage of sequence identity: 100
1tno L - percentage of sequence identity: 100
1tnu B - percentage of sequence identity: 100
1tnu D - percentage of sequence identity: 100
1tnu F - percentage of sequence identity: 100
1tnu H - percentage of sequence identity: 100
1tnu J - percentage of sequence identity: 100
1tnu L - percentage of sequence identity: 100
1tny B - percentage of sequence identity: 100
1tny D - percentage of sequence identity: 100
1tny F - percentage of sequence identity: 100
1tny H - percentage of sequence identity: 100
1tny J - percentage of sequence identity: 100
1tny L - percentage of sequence identity: 100
1tnz B - percentage of sequence identity: 100
1tnz D - percentage of sequence identity: 100
1tnz F - percentage of sequence identity: 100
1tnz H - percentage of sequence identity: 100
1tnz J - percentage of sequence identity: 100
1tnz L - percentage of sequence identity: 100