PDB: 1p9u Compound: putative coronavirus nsp2 (3cl-pro) Classification: HYDROLASE Entry date in PDB: 2003-05-20 Resolution [Å]: 2.37 R-Factor: 0.191

CHAIN: A SWISS-PROT/TREMBL: Q9IW06    KEYWORD: 3D-structure    ATP-binding    Helicase    Hydrolase    Metal-binding    Polyprotein    Repeat    Ribosomal frameshift    RNA-directed RNA polymerase    Thiol protease    Transferase    Transmembrane    Zinc    Zinc-finger    EC: 2.7.7.48 SCOP: b.47.1.4 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Viral cysteine protease of trypsin fold    Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2)    Transmissible gastroenteritis virus GO:  ATP binding    RNA binding    RNA helicase activity    RNA-directed RNA polymerase activity    transcription    viral genome replication    viral life cycle    viral protein processing    CHAIN: B SWISS-PROT/TREMBL: Q9IW06    KEYWORD: 3D-structure    ATP-binding    Helicase    Hydrolase    Metal-binding    Polyprotein    Repeat    Ribosomal frameshift    RNA-directed RNA polymerase    Thiol protease    Transferase    Transmembrane    Zinc    Zinc-finger    EC: 2.7.7.48 SCOP: b.47.1.4 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Viral cysteine protease of trypsin fold    Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2)    Transmissible gastroenteritis virus GO:  ATP binding    RNA binding    RNA helicase activity    RNA-directed RNA polymerase activity    transcription    viral genome replication    viral life cycle    viral protein processing    CHAIN: C SWISS-PROT/TREMBL: Q9IW06    KEYWORD: 3D-structure    ATP-binding    Helicase    Hydrolase    Metal-binding    Polyprotein    Repeat    Ribosomal frameshift    RNA-directed RNA polymerase    Thiol protease    Transferase    Transmembrane    Zinc    Zinc-finger    EC: 2.7.7.48 SCOP: b.47.1.4 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Viral cysteine protease of trypsin fold    Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2)    Transmissible gastroenteritis virus GO:  ATP binding    RNA binding    RNA helicase activity    RNA-directed RNA polymerase activity    transcription    viral genome replication    viral life cycle    viral protein processing    CHAIN: D SWISS-PROT/TREMBL: Q9IW06    KEYWORD: 3D-structure    ATP-binding    Helicase    Hydrolase    Metal-binding    Polyprotein    Repeat    Ribosomal frameshift    RNA-directed RNA polymerase    Thiol protease    Transferase    Transmembrane    Zinc    Zinc-finger    EC: 2.7.7.48 SCOP: b.47.1.4 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Viral cysteine protease of trypsin fold    Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2)    Transmissible gastroenteritis virus GO:  ATP binding    RNA binding    RNA helicase activity    RNA-directed RNA polymerase activity    transcription    viral genome replication    viral life cycle    viral protein processing    CHAIN: E SWISS-PROT/TREMBL: Q9IW06    KEYWORD: 3D-structure    ATP-binding    Helicase    Hydrolase    Metal-binding    Polyprotein    Repeat    Ribosomal frameshift    RNA-directed RNA polymerase    Thiol protease    Transferase    Transmembrane    Zinc    Zinc-finger    EC: 2.7.7.48 SCOP: b.47.1.4 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Viral cysteine protease of trypsin fold    Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2)    Transmissible gastroenteritis virus GO:  ATP binding    RNA binding    RNA helicase activity    RNA-directed RNA polymerase activity    transcription    viral genome replication    viral life cycle    viral protein processing    CHAIN: F SWISS-PROT/TREMBL: Q9IW06    KEYWORD: 3D-structure    ATP-binding    Helicase    Hydrolase    Metal-binding    Polyprotein    Repeat    Ribosomal frameshift    RNA-directed RNA polymerase    Thiol protease    Transferase    Transmembrane    Zinc    Zinc-finger    EC: 2.7.7.48 SCOP: b.47.1.4 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Viral cysteine protease of trypsin fold    Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2)    Transmissible gastroenteritis virus GO:  ATP binding    RNA binding    RNA helicase activity    RNA-directed RNA polymerase activity    transcription    viral genome replication    viral life cycle    viral protein processing

Image Source: PDB

1lvo A - percentage of sequence identity: 100
1p9s A - percentage of sequence identity: 61