PDB: 1sgf Compound: nerve growth factor Classification: GROWTH FACTOR Entry date in PDB: 1998-05-27 Resolution [Å]: 3.15 R-Factor: 0.246

CHAIN: A SWISS-PROT/TREMBL: P00757    KEYWORD: 3D-structure    Growth factor    Metal-binding    Polymorphism    Serine protease homolog    Signal    Zinc    SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    7S NGF protease subunits    Mouse (Mus musculus) GO:  chymotrypsin activity    trypsin activity    proteolysis and peptidolysis    CHAIN: B SWISS-PROT/TREMBL: P01139    KEYWORD: 3D-structure    Growth factor    Signal    SCOP: g.17.1.3 Small proteins    Cystine-knot cytokines    Cystine-knot cytokines    Neurotrophin    beta-Nerve growth factor    Mouse (Mus musculus) GO:  growth factor activity    CHAIN: G SWISS-PROT/TREMBL: P00756    KEYWORD: 3D-structure    Glycoprotein    Growth factor    Hydrolase    Metal-binding    Multigene family    Serine protease    Signal    Zinc    Zymogen    EC: 3.4.21.35 SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    7S NGF protease subunits    Mouse (Mus musculus) GO:  chymotrypsin activity    trypsin activity    proteolysis and peptidolysis    CHAIN: X SWISS-PROT/TREMBL: P00757    KEYWORD: 3D-structure    Growth factor    Metal-binding    Polymorphism    Serine protease homolog    Signal    Zinc    SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    7S NGF protease subunits    Mouse (Mus musculus) GO:  chymotrypsin activity    trypsin activity    proteolysis and peptidolysis    CHAIN: Y SWISS-PROT/TREMBL: P01139    KEYWORD: 3D-structure    Growth factor    Signal    SCOP: g.17.1.3 Small proteins    Cystine-knot cytokines    Cystine-knot cytokines    Neurotrophin    beta-Nerve growth factor    Mouse (Mus musculus) GO:  growth factor activity    CHAIN: Z SWISS-PROT/TREMBL: P00756    KEYWORD: 3D-structure    Glycoprotein    Growth factor    Hydrolase    Metal-binding    Multigene family    Serine protease    Signal    Zinc    Zymogen    EC: 3.4.21.35 SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    7S NGF protease subunits    Mouse (Mus musculus) GO:  chymotrypsin activity    trypsin activity    proteolysis and peptidolysis

Image Source: PDB

1ao5 A - percentage of sequence identity: 71
1bet - - percentage of sequence identity: 100
1ton - - percentage of sequence identity: 63
1www V - percentage of sequence identity: 89
2pka B - percentage of sequence identity: 64