ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 12.1.1

Subclass Accession number: 9244
Subclass: 12.1.1

Type: HH alpha-alpha
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Number of loops: 5

Average sequence ID (%) : 58.8 +/- 20.3
Average RMSD (Å) : 0.360 +/- 0.089

Consensus geometry

d (Å): 5

delta (°): 0-45

theta (°): 0-45

rho (°): 135-180

Consensus Sequence:	MhGXTNPApXhPGTIR
(φψ)-conformation:	aaepapaaapppgpaa

Pattern:	[AV]	[V]	[akl]	[AST]	[AGNS]	[R]	x	[IM]	[ILM]	[G]	x	[T]	[DN]	[PS]	[AL]	[ADEQ]	[AS]	[AKL]	[EP]	[G]	[ST]	[I]	[R]	[GK]	[D]	[F]
Conservation:	-0.474	0.484	-1.351	-0.643	-0.961	1.013	-1.738	-0.009	-0.291	1.542	-1.451	1.013	0.361	0.001	-0.705	-0.961	-0.310	-1.230	0.028	1.542	-0.000	0.484	1.013	-0.437	1.542	1.542

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1ehw_A_83	1ehw	A	83	108	VVRASRAMIGHTDSAEAAPGTIRGDF	HHHHHHHHH--SSGGGS-TTSHHHHH	aaaaaaaaaepaxaaaxxxgxaaaaa
1nhk_L_82	1nhk	L	82	107	AVLANRDIMGATNPAQAAEGTIRKDF	HHHHHHHHH--SSGGG--TTSHHHHH	aaaaaaaaaepaxaaaxxxvxaaaaa
1npk_*_87	1npk	-	87	112	VVASARLMIGVTNPLASAPGSIRGDF	HHHHHHHHH--SSGGGS-TTSHHHHH	aaaaaaaaaebaxaaaxxpgxaaaaa
1nsq_A_84	1nsq	A	84	109	VVKTGRQMLGATNPADSLPGTIRGDF	HHHHHHHHH--SSGGGS-TTSHHHHH	aaaaaaaaaexaxaaaxxpgxaaaaa
1nue_A_83	1nue	A	83	108	VVKTGRVMLGETNPADSKPGTIRGDF	HHHHHHHHH--SSGGG--TTSHHHHH	aaaaaaaaaexaxaaaxxpgxaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1nhk_L_82	1nhk	L	CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE	T - 93
1nhk_L_82	1nhk	L	CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE	R - 104
1nsq_A_84	1nsq	A	PHSPHOSPHONO GROUP	R - 89
1nsq_A_84	1nsq	A	PHSPHOSPHONO GROUP	R - 106
1nue_A_83	1nue	A	GDPGUANOSINE-5'-DIPHOSPHATE	R - 88
1nue_A_83	1nue	A	MGMAGNESIUM ION	R - 88
1nue_A_83	1nue	A	GDPGUANOSINE-5'-DIPHOSPHATE	G - 92
1nue_A_83	1nue	A	GDPGUANOSINE-5'-DIPHOSPHATE	E - 93
1nue_A_83	1nue	A	GDPGUANOSINE-5'-DIPHOSPHATE	T - 94
1nue_A_83	1nue	A	GDPGUANOSINE-5'-DIPHOSPHATE	R - 105

Clusters included in this Subclass