PDB: 2tsr Compound: thymidylate synthase Classification: METHYLTRANSFERASE Entry date in PDB: 1999-02-16 Resolution [Å]: 2.60 R-Factor: 0.162

CHAIN: A SWISS-PROT/TREMBL: P45352    KEYWORD: 3D-structure    Methyltransferase    Nucleotide biosynthesis    Transferase    EC: 2.1.1.45 SCOP: d.117.1.1 Alpha and beta proteins (a+b)    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase    Rat (Rattus norvegicus) GO:  thymidylate synthase activity    dTMP biosynthesis    CHAIN: B SWISS-PROT/TREMBL: P45352    KEYWORD: 3D-structure    Methyltransferase    Nucleotide biosynthesis    Transferase    EC: 2.1.1.45 SCOP: d.117.1.1 Alpha and beta proteins (a+b)    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase    Rat (Rattus norvegicus) GO:  thymidylate synthase activity    dTMP biosynthesis    CHAIN: C SWISS-PROT/TREMBL: P45352    KEYWORD: 3D-structure    Methyltransferase    Nucleotide biosynthesis    Transferase    EC: 2.1.1.45 SCOP: d.117.1.1 Alpha and beta proteins (a+b)    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase    Rat (Rattus norvegicus) GO:  thymidylate synthase activity    dTMP biosynthesis    CHAIN: D SWISS-PROT/TREMBL: P45352    KEYWORD: 3D-structure    Methyltransferase    Nucleotide biosynthesis    Transferase    EC: 2.1.1.45 SCOP: d.117.1.1 Alpha and beta proteins (a+b)    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase    Rat (Rattus norvegicus) GO:  thymidylate synthase activity    dTMP biosynthesis

Image Source: PDB

1f28 A - percentage of sequence identity: 61
1hvy A - percentage of sequence identity: 92
1hw3 A - percentage of sequence identity: 88