ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 6.18.1

Subclass Accession number: 2504
Subclass: 6.18.1

Type: HH alpha-alpha
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 2.7.1 (>75 %)  2.7.1.37
GO : GO:0003723 (>50 %)  GO:0003724 (>50 %)  GO:0004386 (>75 %)  GO:0004672 (>50 %)  GO:0005509 (>75 %)  GO:0005524 (>75 %)  GO:0008026 (>75 %)  GO:0016301 (>50 %)  GO:0016462 (>75 %)  GO:0016773 (>50 %)  GO:0016817 (>75 %)  GO:0016818 (>75 %)
SCOP : 47472 (>75 %)  47473 (>75 %)  47492 (>75 %)  52539 (>75 %)  52540 (>75 %)  56111 (>75 %)  56112 (>75 %)  81268 (>75 %)  88854 (>75 %)

Number of loops: 3

Average sequence ID (%) : 33.3 +/- 17.0
Average RMSD (Å) : 0.400 +/- 0.100

Consensus geometry

d (Å): 17

delta (°): 45-90

theta (°): 135-180

rho (°): 0-45

Consensus Sequence:	XhXhppPpXI
(φψ)-conformation:	aagpabppaa

Pattern:	[EPR]	x	[IL]	[IL]	[EMR]	[AG]	[IV]	[FK]	[EGT]	[LMY]	[GR]	[FW]	[EY]	[EK]	[P]	[ST]	[AEP]	[I]	[Q]	[EQ]	[ER]	x	[I]	[MP]	[GIP]	[AI]	[IL]
Conservation:	-0.857	-1.285	0.321	0.321	-0.999	0.205	0.627	-0.611	-1.214	-0.500	-0.308	1.147	-0.365	0.364	2.856	0.112	-0.928	0.928	1.571	0.666	0.099	-1.071	0.928	-0.041	-1.713	-0.580	0.325

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1q0u_A_13	1q0u	A	13	39	PFIIEAIKTLRFYKPTEIQERIIPGAL	HHHHHHHHHTT--S--HHHHHHHHHHH	aaaaaaaaaavxabpxaaaaaaaaaaa
1qde_A_30	1qde	A	30	56	ENLLRGVFGYGFEEPSAIQQRAIMPII	HHHHHHHHHHT--S--HHHHHHHHHHH	aaaaaaaaaagxabxxaaaaaaaaaaa
1vec_A_94	1vec	A	94	120	RELLMGIFEMGWEKPSPIQEESIPIAL	HHHHHHHHTTT--S--HHHHHHHHHHH	aaaaaaaaaagxabxxaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1q0u_A_13	1q0u	A	MSESELENOMETHIONINE	F - 14
1q0u_A_13	1q0u	A	MSESELENOMETHIONINE	I - 15
1q0u_A_13	1q0u	A	MSESELENOMETHIONINE	R - 33
1q0u_A_13	1q0u	A	MSESELENOMETHIONINE	I - 34
1q0u_A_13	1q0u	A	MSESELENOMETHIONINE	I - 35
1q0u_A_13	1q0u	A	MSESELENOMETHIONINE	P - 36
1q0u_A_13	1q0u	A	MSESELENOMETHIONINE	G - 37
1q0u_A_13	1q0u	A	MSESELENOMETHIONINE	A - 38
1vec_A_94	1vec	A	ZN2ZINC ION ON 3-FOLD CRYSTAL AXIS	M - 98
1vec_A_94	1vec	A	ZN2ZINC ION ON 3-FOLD CRYSTAL AXIS	E - 102

Clusters included in this Subclass