ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 4.22.1

Subclass Accession number: 1301
Subclass: 4.22.1

Type: EH beta-alpha
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : - (>50 %)  1 (>75 %)
GO : GO:0004601 (>50 %)  GO:0016684 (>50 %)
SCOP : 52832 (>75 %)  52833 (>75 %)  52901 (>75 %)

Number of loops: 9

Average sequence ID (%) : 16.2 +/- 22.9
Average RMSD (Å) : 0.744 +/- 0.309

Consensus geometry

d (Å): 11

delta (°): 0-45

theta (°): 45-90

rho (°): 225-270

Consensus Sequence:	XXhhXchp
(φψ)-conformation:	bbaaapaa

Pattern:	x	[fhqy]	x	[fgpy]	[aglw]	x	[DKNS]	[GPSTV]	[ADER]	[anstv]	[aikmv]
Conservation:	-1.000	-0.159	-0.015	-0.069	-1.154	-1.078	2.346	-0.212	0.876	-0.170	-0.364

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1a0c_A_240	1a0c	A	240	249	.HQYDFDVANV	.EESS-SHHHH	.bxaaabaaaa
1elj_A_181	1elj	A	181	190	.QPGLDKPETI	.EE-TTSHHHH	.bxaaaxaaaa
1ep3_A_143	1ep3	A	143	152	.QAFGTDPEVA	.EEGGG-HHHH	.xxaaabaaaa
1f2v_A_96	1f2v	A	96	106	VICTLRDPRTP	EEE-TTSTHHH	bbbaaapaaaa
1jeh_A_386	1jeh	A	390	400	KFPFAANSRAK	EEETTS-HHHH	xbxaaaxaaaa
1k92_A_151	1k92	A	152	162	IYKPWLDTDFI	EE-GGG-HHHH	bxbaaaxaaaa
1lvl_*_366	1lvl	-	370	380	QFPFAANGRAM	EEEGGG-HHHH	bbxaaabaaaa
1ou0_A_94	1ou0	A	95	105	VVCYLNDVRSK	EEE-TT-HHHH	bbbaaaxaaaa
3lad_A_379	3lad	A	383	393	VFPFAASGRAM	EEEGGG-HHHH	bbxaaaxaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1k92_A_151	1k92	A	CRYPROPANE-1,2,3-TRIOL	E - 164
1ou0_A_94	1ou0	A	MSESELENOMETHIONINE	V - 102
1ou0_A_94	1ou0	A	MSESELENOMETHIONINE	R - 103
1ou0_A_94	1ou0	A	MSESELENOMETHIONINE	S - 104
1ou0_A_94	1ou0	A	MSESELENOMETHIONINE	K - 105

Clusters included in this Subclass

CLUSTER: EH.3.99

CLUSTER: EH.4.111