ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 6.5.1

Subclass Accession number: 2490
Subclass: 6.5.1

Type: HH alpha-alpha
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 2.5 (>75 %)  2.5.1 (>75 %)  2.5.1.18
GO : GO:0004364 (>75 %)  GO:0016765 (>75 %)
SCOP : 47615 (>75 %)  47616 (>75 %)  47617 (>75 %)

Number of loops: 8

Average sequence ID (%) : 8.3 +/- 9.7
Average RMSD (Å) : 1.338 +/- 0.403

Consensus geometry

d (Å): 15

delta (°): 90-135

theta (°): 90-135

rho (°): 315-360

Consensus Sequence:	XXXXphpXpX
(φψ)-conformation:	aalppaapaa

Pattern:	[AILVY]	x	x	x	[afim]	x	x	x	x	x	[DKNPT]	[ailpv]	[aknrst]	x	[egpqs]	x	x	[FHILV]	x	x	[afklt]	x
Conservation:	1.822	-1.516	-0.015	0.273	0.606	-0.919	-0.948	-0.456	0.719	-0.372	1.887	-0.115	0.610	0.634	1.109	-1.489	-0.403	1.337	-1.210	-0.916	-0.520	-0.121

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1cke_A_36	1cke	A	43	64	LALAALHHHVDVASEDALVPLA	HHHHHHHHT--TT-HHHHHHHH	aaaaaaaavxxaaxaaaaaaaa
1fc3_A_141	1fc3	A	149	170	ITSIIHEIGVPAHIKGYLYLRE	HHHHHHHHT--TTSHHHHHHHH	aaaaaaaagxxaaxaaaaaaaa
1l5o_A_210	1l5o	A	217	238	VRRAIAINQPNPRDGIDVLSKV	HHHHHHHH---TT-HHHHHHHH	aaaaaaaalxxaabaaaaaaaa
1one_A_72	1one	A	72	93	IAPAFVKANIDVKDQKAVDDFL	HHHHHHHHT--TT-HHHHHHHH	aaaaaaaalxxaaxaaaaaaaa
1pb6_A_176	1pb6	A	176	197	APQVEAVTGATLRDEVFFNQTV	HHHHHHHHS--TTSHHHHHHHH	aaaaaaaavbbaaxaaaaaaaa
1po5_A_264	1po5	A	268	289	YLLRMEKDKSDPSSEFHHQNLI	HHHHHHHHT--TT-HHHHHHHH	aaaaaaaavxpaapaaaaaaaa
1r4w_A_114	1r4w	A	121	142	LWMRIWSRDEDITESQNILSAA	HHHHHHTS----SSHHHHHHHH	aaaaaaaalxxaaxaaaaaaaa
4ubp_C_311	4ubp	C	316	337	LDMLMVCHHLKQNIPEDVAFAD	HHHHHHHHT--TTSHHHHHHHH	aaaaaaaalxxaaxaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1l5o_A_210	1l5o	A	NCNNICOTINATE MONONUCLEOTIDE	K - 213
1po5_A_264	1po5	A	HEMPROTOPORPHYRIN IX CONTAINING FE	S - 294
1po5_A_264	1po5	A	HEMPROTOPORPHYRIN IX CONTAINING FE	L - 295
1po5_A_264	1po5	A	HEMPROTOPORPHYRIN IX CONTAINING FE	F - 296
1po5_A_264	1po5	A	HEMPROTOPORPHYRIN IX CONTAINING FE	A - 298
1po5_A_264	1po5	A	HEMPROTOPORPHYRIN IX CONTAINING FE	G - 299
1po5_A_264	1po5	A	HEMPROTOPORPHYRIN IX CONTAINING FE	T - 300
1po5_A_264	1po5	A	HEMPROTOPORPHYRIN IX CONTAINING FE	T - 302
1po5_A_264	1po5	A	HEMPROTOPORPHYRIN IX CONTAINING FE	T - 303
1po5_A_264	1po5	A	HEMPROTOPORPHYRIN IX CONTAINING FE	T - 306
4ubp_C_311	4ubp	C	HAEACETOHYDROXAMIC ACID	H - 323
4ubp_C_311	4ubp	C	HAEACETOHYDROXAMIC ACID	R - 339

Clusters included in this Subclass

CLUSTER: HH.5.121

CLUSTER: HH.5.224

CLUSTER: HH.7.15